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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Septin-8
Full Name:
Septin-8
Alias:
KIAA0202; SEP2; Septin 8
Type:
Mass (Da):
55738
Number AA:
483
UniProt ID:
Q92599
International Prot ID:
IPI00022082
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031105
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007049
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
A
T
D
L
E
R
F
S
N
A
E
P
E
P
R
Site 2
S18
N
A
E
P
E
P
R
S
L
S
L
G
G
H
V
Site 3
S20
E
P
E
P
R
S
L
S
L
G
G
H
V
G
F
Site 4
S29
G
G
H
V
G
F
D
S
L
P
D
Q
L
V
S
Site 5
S36
S
L
P
D
Q
L
V
S
K
S
V
T
Q
G
F
Site 6
S38
P
D
Q
L
V
S
K
S
V
T
Q
G
F
S
F
Site 7
T59
E
T
G
I
G
K
S
T
L
M
N
T
L
F
N
Site 8
T63
G
K
S
T
L
M
N
T
L
F
N
T
T
F
E
Site 9
T71
L
F
N
T
T
F
E
T
E
E
A
S
H
H
E
Site 10
T87
C
V
R
L
R
P
Q
T
Y
D
L
Q
E
S
N
Site 11
Y88
V
R
L
R
P
Q
T
Y
D
L
Q
E
S
N
V
Site 12
S116
D
Q
I
N
K
D
E
S
Y
R
P
I
V
D
Y
Site 13
Y117
Q
I
N
K
D
E
S
Y
R
P
I
V
D
Y
I
Site 14
Y123
S
Y
R
P
I
V
D
Y
I
D
A
Q
F
E
N
Site 15
S141
E
E
L
K
I
R
R
S
L
F
D
Y
H
D
T
Site 16
Y145
I
R
R
S
L
F
D
Y
H
D
T
R
I
H
V
Site 17
S163
F
I
T
P
T
G
H
S
L
K
S
L
D
L
V
Site 18
S166
P
T
G
H
S
L
K
S
L
D
L
V
T
M
K
Site 19
T171
L
K
S
L
D
L
V
T
M
K
K
L
D
S
K
Site 20
T190
P
I
I
A
K
A
D
T
I
S
K
S
E
L
H
Site 21
S192
I
A
K
A
D
T
I
S
K
S
E
L
H
K
F
Site 22
S194
K
A
D
T
I
S
K
S
E
L
H
K
F
K
I
Site 23
Y215
V
S
N
G
V
Q
I
Y
Q
F
P
T
D
D
E
Site 24
Y258
K
L
V
R
A
R
Q
Y
P
W
G
V
V
Q
V
Site 25
T292
M
E
D
L
R
E
Q
T
H
S
R
H
Y
E
L
Site 26
S294
D
L
R
E
Q
T
H
S
R
H
Y
E
L
Y
R
Site 27
Y297
E
Q
T
H
S
R
H
Y
E
L
Y
R
R
C
K
Site 28
Y300
H
S
R
H
Y
E
L
Y
R
R
C
K
L
E
E
Site 29
S313
E
E
M
G
F
Q
D
S
D
G
D
S
Q
P
F
Site 30
S317
F
Q
D
S
D
G
D
S
Q
P
F
S
L
Q
E
Site 31
S321
D
G
D
S
Q
P
F
S
L
Q
E
T
Y
E
A
Site 32
T325
Q
P
F
S
L
Q
E
T
Y
E
A
K
R
K
E
Site 33
Y326
P
F
S
L
Q
E
T
Y
E
A
K
R
K
E
F
Site 34
S335
A
K
R
K
E
F
L
S
E
L
Q
R
K
E
E
Site 35
S417
S
Q
A
L
H
A
T
S
Q
Q
P
L
R
K
D
Site 36
S431
D
K
D
K
K
N
R
S
D
I
G
A
H
Q
P
Site 37
S441
G
A
H
Q
P
G
M
S
L
S
S
S
K
V
M
Site 38
S443
H
Q
P
G
M
S
L
S
S
S
K
V
M
M
T
Site 39
S445
P
G
M
S
L
S
S
S
K
V
M
M
T
K
A
Site 40
S453
K
V
M
M
T
K
A
S
V
E
P
L
N
C
S
Site 41
T477
S
C
L
V
R
D
A
T
W
R
E
G
F
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation