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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PIGB
Full Name:
GPI mannosyltransferase 3
Alias:
GPI mannosyltransferase 3: GPI mannosyltransferase III: Phosphatidylinositol-glycan biosynthesis class B protein; GPI mannosyltransferase III; GPI-MT-III; Phosphatidylinositol glycan anchor biosynthesis, class B
Type:
Transferase; EC 2.4.1.-; Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Endoplasmic reticulum
Mass (Da):
65056
Number AA:
554
UniProt ID:
Q92521
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0031227
Uniprot
OncoNet
Molecular Function:
GO:0004376
PhosphoSite+
KinaseNET
Biological Process:
GO:0016254
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
E
P
G
G
G
D
A
S
L
T
L
H
G
L
Q
Site 2
T20
G
G
G
D
A
S
L
T
L
H
G
L
Q
N
R
Site 3
S39
I
K
L
R
K
R
K
S
T
L
Y
F
N
T
Q
Site 4
T40
K
L
R
K
R
K
S
T
L
Y
F
N
T
Q
E
Site 5
Y42
R
K
R
K
S
T
L
Y
F
N
T
Q
E
K
S
Site 6
T45
K
S
T
L
Y
F
N
T
Q
E
K
S
A
R
R
Site 7
S49
Y
F
N
T
Q
E
K
S
A
R
R
R
G
D
L
Site 8
Y87
T
S
F
V
P
D
E
Y
W
Q
S
L
E
V
S
Site 9
S114
E
W
T
E
R
L
R
S
Y
T
Y
P
L
I
F
Site 10
Y115
W
T
E
R
L
R
S
Y
T
Y
P
L
I
F
A
Site 11
T116
T
E
R
L
R
S
Y
T
Y
P
L
I
F
A
S
Site 12
S160
V
A
D
V
R
L
Y
S
L
M
K
Q
L
E
N
Site 13
S215
Y
P
L
E
G
S
K
S
M
N
S
V
K
Y
S
Site 14
S218
E
G
S
K
S
M
N
S
V
K
Y
S
S
L
V
Site 15
T234
L
A
F
I
I
R
P
T
A
V
I
L
W
T
P
Site 16
T240
P
T
A
V
I
L
W
T
P
L
L
F
R
H
F
Site 17
Y332
P
F
F
I
H
G
C
Y
L
A
P
K
R
Y
R
Site 18
T379
V
F
C
G
Y
S
L
T
H
L
K
T
W
K
K
Site 19
T383
Y
S
L
T
H
L
K
T
W
K
K
P
A
L
S
Site 20
Y402
S
N
L
F
L
A
L
Y
T
G
L
V
H
Q
R
Site 21
Y423
S
H
I
Q
K
V
C
Y
N
N
P
N
K
S
S
Site 22
Y445
P
C
H
S
T
P
Y
Y
S
H
V
H
C
P
L
Site 23
T464
L
Q
C
P
P
D
L
T
G
K
S
H
Y
L
D
Site 24
S493
R
E
F
H
D
D
A
S
L
P
T
H
L
I
T
Site 25
T526
R
T
A
V
F
F
H
T
H
L
P
E
G
R
I
Site 26
S535
L
P
E
G
R
I
G
S
H
I
Y
V
Y
E
R
Site 27
Y538
G
R
I
G
S
H
I
Y
V
Y
E
R
K
L
K
Site 28
Y540
I
G
S
H
I
Y
V
Y
E
R
K
L
K
G
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation