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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SEC14L1
Full Name:
SEC14-like protein 1
Alias:
PRELID4A; S14L1; SEC14L; SEC14-like 1
Type:
Mass (Da):
81280
Number AA:
UniProt ID:
Q92503
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y5
_
_
_
M
V
Q
K
Y
Q
S
P
V
R
V
Y
Site 2
Y12
Y
Q
S
P
V
R
V
Y
K
Y
P
F
E
L
I
Site 3
Y23
F
E
L
I
M
A
A
Y
E
R
R
F
P
T
C
Site 4
T41
P
M
F
V
G
S
D
T
V
S
E
F
K
S
E
Site 5
S43
F
V
G
S
D
T
V
S
E
F
K
S
E
D
G
Site 6
S47
D
T
V
S
E
F
K
S
E
D
G
A
I
H
V
Site 7
Y77
K
K
I
A
G
V
D
Y
V
Y
F
V
Q
K
N
Site 8
Y79
I
A
G
V
D
Y
V
Y
F
V
Q
K
N
S
L
Site 9
S88
V
Q
K
N
S
L
N
S
R
E
R
T
L
H
I
Site 10
T92
S
L
N
S
R
E
R
T
L
H
I
E
A
Y
N
Site 11
Y98
R
T
L
H
I
E
A
Y
N
E
T
F
S
N
R
Site 12
S136
S
A
S
L
D
I
K
S
F
F
G
F
E
S
T
Site 13
Y165
K
G
K
E
I
I
E
Y
Y
L
R
Q
L
E
E
Site 14
Y166
G
K
E
I
I
E
Y
Y
L
R
Q
L
E
E
E
Site 15
T176
Q
L
E
E
E
G
I
T
F
V
P
R
W
S
P
Site 16
S182
I
T
F
V
P
R
W
S
P
P
S
I
T
P
S
Site 17
S185
V
P
R
W
S
P
P
S
I
T
P
S
S
E
T
Site 18
T187
R
W
S
P
P
S
I
T
P
S
S
E
T
S
S
Site 19
S189
S
P
P
S
I
T
P
S
S
E
T
S
S
S
S
Site 20
S190
P
P
S
I
T
P
S
S
E
T
S
S
S
S
S
Site 21
T192
S
I
T
P
S
S
E
T
S
S
S
S
S
K
K
Site 22
S193
I
T
P
S
S
E
T
S
S
S
S
S
K
K
Q
Site 23
S194
T
P
S
S
E
T
S
S
S
S
S
K
K
Q
A
Site 24
S195
P
S
S
E
T
S
S
S
S
S
K
K
Q
A
A
Site 25
S196
S
S
E
T
S
S
S
S
S
K
K
Q
A
A
S
Site 26
S197
S
E
T
S
S
S
S
S
K
K
Q
A
A
S
M
Site 27
S218
A
A
L
K
E
G
L
S
G
D
A
L
S
S
P
Site 28
S223
G
L
S
G
D
A
L
S
S
P
S
A
P
E
P
Site 29
S224
L
S
G
D
A
L
S
S
P
S
A
P
E
P
V
Site 30
S226
G
D
A
L
S
S
P
S
A
P
E
P
V
V
G
Site 31
T234
A
P
E
P
V
V
G
T
P
D
D
K
L
D
A
Site 32
Y247
D
A
D
H
I
K
R
Y
L
G
D
L
T
P
L
Site 33
T252
K
R
Y
L
G
D
L
T
P
L
Q
E
S
C
L
Site 34
Y312
R
K
Q
H
Q
V
D
Y
I
L
E
T
W
T
P
Site 35
T318
D
Y
I
L
E
T
W
T
P
P
Q
V
L
Q
D
Site 36
Y326
P
P
Q
V
L
Q
D
Y
Y
A
G
G
W
H
H
Site 37
Y342
D
K
D
G
R
P
L
Y
V
L
R
L
G
Q
M
Site 38
Y366
G
E
E
A
L
L
R
Y
V
L
S
V
N
E
E
Site 39
S369
A
L
L
R
Y
V
L
S
V
N
E
E
R
L
R
Site 40
T382
L
R
R
C
E
E
N
T
K
V
F
G
R
P
I
Site 41
Y425
I
E
V
V
E
A
N
Y
P
E
T
L
G
R
L
Site 42
T456
S
P
F
I
D
D
N
T
R
R
K
F
L
I
Y
Site 43
Y463
T
R
R
K
F
L
I
Y
A
G
N
D
Y
Q
G
Site 44
S504
E
G
G
L
V
P
K
S
L
Y
R
T
A
E
E
Site 45
T508
V
P
K
S
L
Y
R
T
A
E
E
L
E
N
E
Site 46
Y525
K
L
W
T
E
T
I
Y
Q
S
A
S
V
F
K
Site 47
S529
E
T
I
Y
Q
S
A
S
V
F
K
G
A
P
H
Site 48
Y565
G
D
I
V
F
N
I
Y
H
S
K
R
S
P
Q
Site 49
S567
I
V
F
N
I
Y
H
S
K
R
S
P
Q
P
P
Site 50
S570
N
I
Y
H
S
K
R
S
P
Q
P
P
K
K
D
Site 51
S578
P
Q
P
P
K
K
D
S
L
G
A
H
S
I
T
Site 52
S583
K
D
S
L
G
A
H
S
I
T
S
P
G
G
N
Site 53
T585
S
L
G
A
H
S
I
T
S
P
G
G
N
N
V
Site 54
S586
L
G
A
H
S
I
T
S
P
G
G
N
N
V
Q
Site 55
Y605
V
W
Q
L
G
R
D
Y
S
M
V
E
S
P
L
Site 56
S606
W
Q
L
G
R
D
Y
S
M
V
E
S
P
L
I
Site 57
S610
R
D
Y
S
M
V
E
S
P
L
I
C
K
E
G
Site 58
S623
E
G
E
S
V
Q
G
S
H
V
T
R
W
P
G
Site 59
S640
I
L
Q
W
K
F
H
S
M
P
A
C
A
A
S
Site 60
S658
R
V
D
D
V
L
A
S
L
Q
V
S
S
H
K
Site 61
S663
L
A
S
L
Q
V
S
S
H
K
C
K
V
M
Y
Site 62
Y670
S
H
K
C
K
V
M
Y
Y
T
E
V
I
G
S
Site 63
Y671
H
K
C
K
V
M
Y
Y
T
E
V
I
G
S
E
Site 64
T672
K
C
K
V
M
Y
Y
T
E
V
I
G
S
E
D
Site 65
S677
Y
Y
T
E
V
I
G
S
E
D
F
R
G
S
M
Site 66
S683
G
S
E
D
F
R
G
S
M
T
S
L
E
S
S
Site 67
T685
E
D
F
R
G
S
M
T
S
L
E
S
S
H
S
Site 68
S686
D
F
R
G
S
M
T
S
L
E
S
S
H
S
G
Site 69
S689
G
S
M
T
S
L
E
S
S
H
S
G
F
S
Q
Site 70
S690
S
M
T
S
L
E
S
S
H
S
G
F
S
Q
L
Site 71
S692
T
S
L
E
S
S
H
S
G
F
S
Q
L
S
A
Site 72
S698
H
S
G
F
S
Q
L
S
A
A
T
T
S
S
S
Site 73
T701
F
S
Q
L
S
A
A
T
T
S
S
S
Q
S
H
Site 74
T702
S
Q
L
S
A
A
T
T
S
S
S
Q
S
H
S
Site 75
S703
Q
L
S
A
A
T
T
S
S
S
Q
S
H
S
S
Site 76
S704
L
S
A
A
T
T
S
S
S
Q
S
H
S
S
S
Site 77
S705
S
A
A
T
T
S
S
S
Q
S
H
S
S
S
M
Site 78
S707
A
T
T
S
S
S
Q
S
H
S
S
S
M
I
S
Site 79
S709
T
S
S
S
Q
S
H
S
S
S
M
I
S
R
_
Site 80
S710
S
S
S
Q
S
H
S
S
S
M
I
S
R
_
_
Site 81
S711
S
S
Q
S
H
S
S
S
M
I
S
R
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation