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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
STARD8
Full Name:
StAR-related lipid transfer protein 8
Alias:
STAR8; START domain-containing protein 8
Type:
Intracellular, Cell junction protein
Mass (Da):
112601
Number AA:
1023
UniProt ID:
Q92502
International Prot ID:
IPI00742801
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005925
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005096
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T2
_
_
_
_
_
_
M
T
L
N
N
C
A
S
M
Site 2
S8
M
T
L
N
N
C
A
S
M
K
L
E
V
H
F
Site 3
S23
Q
S
K
Q
N
E
D
S
E
E
E
E
Q
C
T
Site 4
T30
S
E
E
E
E
Q
C
T
I
S
S
H
W
A
F
Site 5
S45
Q
Q
E
S
K
C
W
S
P
M
G
S
S
D
L
Site 6
S49
K
C
W
S
P
M
G
S
S
D
L
L
A
P
P
Site 7
S50
C
W
S
P
M
G
S
S
D
L
L
A
P
P
S
Site 8
S57
S
D
L
L
A
P
P
S
P
G
L
P
A
T
S
Site 9
T63
P
S
P
G
L
P
A
T
S
S
C
E
S
V
L
Site 10
S65
P
G
L
P
A
T
S
S
C
E
S
V
L
T
E
Site 11
S100
P
L
P
G
R
A
P
S
S
S
D
R
P
L
L
Site 12
S101
L
P
G
R
A
P
S
S
S
D
R
P
L
L
S
Site 13
S102
P
G
R
A
P
S
S
S
D
R
P
L
L
S
P
Site 14
S108
S
S
D
R
P
L
L
S
P
T
Q
G
Q
E
G
Site 15
S128
K
K
R
H
R
N
R
S
F
L
K
H
L
E
S
Site 16
S135
S
F
L
K
H
L
E
S
L
R
R
K
E
K
S
Site 17
S142
S
L
R
R
K
E
K
S
G
S
Q
Q
A
E
P
Site 18
S144
R
R
K
E
K
S
G
S
Q
Q
A
E
P
K
H
Site 19
S152
Q
Q
A
E
P
K
H
S
P
A
T
S
E
K
V
Site 20
S156
P
K
H
S
P
A
T
S
E
K
V
S
K
A
S
Site 21
S160
P
A
T
S
E
K
V
S
K
A
S
S
F
R
S
Site 22
S163
S
E
K
V
S
K
A
S
S
F
R
S
C
R
G
Site 23
S164
E
K
V
S
K
A
S
S
F
R
S
C
R
G
F
Site 24
S167
S
K
A
S
S
F
R
S
C
R
G
F
L
S
A
Site 25
S173
R
S
C
R
G
F
L
S
A
G
F
Y
R
A
K
Site 26
Y177
G
F
L
S
A
G
F
Y
R
A
K
N
W
A
A
Site 27
S186
A
K
N
W
A
A
T
S
A
G
G
S
G
A
N
Site 28
S190
A
A
T
S
A
G
G
S
G
A
N
T
R
K
A
Site 29
T194
A
G
G
S
G
A
N
T
R
K
A
W
E
A
W
Site 30
T229
P
G
D
H
K
P
G
T
F
P
R
S
L
S
I
Site 31
S233
K
P
G
T
F
P
R
S
L
S
I
E
S
L
C
Site 32
S235
G
T
F
P
R
S
L
S
I
E
S
L
C
P
E
Site 33
S238
P
R
S
L
S
I
E
S
L
C
P
E
D
G
H
Site 34
S264
G
C
E
G
R
R
G
S
C
G
S
T
G
S
H
Site 35
S267
G
R
R
G
S
C
G
S
T
G
S
H
A
S
T
Site 36
T268
R
R
G
S
C
G
S
T
G
S
H
A
S
T
Y
Site 37
S270
G
S
C
G
S
T
G
S
H
A
S
T
Y
D
N
Site 38
S273
G
S
T
G
S
H
A
S
T
Y
D
N
L
P
E
Site 39
T274
S
T
G
S
H
A
S
T
Y
D
N
L
P
E
L
Site 40
Y275
T
G
S
H
A
S
T
Y
D
N
L
P
E
L
Y
Site 41
Y282
Y
D
N
L
P
E
L
Y
P
A
E
P
V
M
V
Site 42
S301
E
D
E
D
D
E
E
S
G
G
S
Y
A
H
L
Site 43
S304
D
D
E
E
S
G
G
S
Y
A
H
L
D
D
I
Site 44
Y305
D
E
E
S
G
G
S
Y
A
H
L
D
D
I
L
Site 45
S326
Q
Q
R
V
E
L
W
S
R
A
M
Y
P
D
L
Site 46
Y330
E
L
W
S
R
A
M
Y
P
D
L
G
P
G
D
Site 47
T344
D
E
E
E
E
E
A
T
S
S
V
E
I
A
T
Site 48
S345
E
E
E
E
E
A
T
S
S
V
E
I
A
T
V
Site 49
S346
E
E
E
E
A
T
S
S
V
E
I
A
T
V
E
Site 50
S362
K
C
Q
A
E
A
L
S
Q
M
E
V
P
A
H
Site 51
S372
E
V
P
A
H
G
E
S
P
A
W
A
Q
A
E
Site 52
S417
A
P
A
P
A
Q
D
S
E
Q
E
A
H
S
G
Site 53
T428
A
H
S
G
G
E
P
T
F
A
S
S
L
S
V
Site 54
S431
G
G
E
P
T
F
A
S
S
L
S
V
E
E
G
Site 55
S432
G
E
P
T
F
A
S
S
L
S
V
E
E
G
H
Site 56
S434
P
T
F
A
S
S
L
S
V
E
E
G
H
S
I
Site 57
S440
L
S
V
E
E
G
H
S
I
S
D
T
V
A
S
Site 58
S442
V
E
E
G
H
S
I
S
D
T
V
A
S
S
S
Site 59
T444
E
G
H
S
I
S
D
T
V
A
S
S
S
E
L
Site 60
S447
S
I
S
D
T
V
A
S
S
S
E
L
D
S
S
Site 61
S448
I
S
D
T
V
A
S
S
S
E
L
D
S
S
G
Site 62
S449
S
D
T
V
A
S
S
S
E
L
D
S
S
G
N
Site 63
S453
A
S
S
S
E
L
D
S
S
G
N
S
M
N
E
Site 64
S454
S
S
S
E
L
D
S
S
G
N
S
M
N
E
A
Site 65
S457
E
L
D
S
S
G
N
S
M
N
E
A
E
A
A
Site 66
S473
P
L
A
G
L
Q
A
S
M
P
R
E
R
R
D
Site 67
S481
M
P
R
E
R
R
D
S
G
V
G
A
S
L
T
Site 68
S486
R
D
S
G
V
G
A
S
L
T
R
P
C
R
K
Site 69
T488
S
G
V
G
A
S
L
T
R
P
C
R
K
L
R
Site 70
S498
C
R
K
L
R
W
H
S
F
Q
N
S
H
R
P
Site 71
S502
R
W
H
S
F
Q
N
S
H
R
P
S
L
N
S
Site 72
S506
F
Q
N
S
H
R
P
S
L
N
S
E
S
L
E
Site 73
S509
S
H
R
P
S
L
N
S
E
S
L
E
I
N
R
Site 74
S511
R
P
S
L
N
S
E
S
L
E
I
N
R
Q
F
Site 75
T534
K
G
S
L
L
R
L
T
A
F
M
E
K
Y
T
Site 76
Y540
L
T
A
F
M
E
K
Y
T
V
P
H
K
Q
G
Site 77
T561
K
F
M
R
R
N
K
T
P
D
Y
R
G
Q
H
Site 78
Y564
R
R
N
K
T
P
D
Y
R
G
Q
H
V
F
G
Site 79
S588
T
G
Q
P
L
P
Q
S
I
Q
Q
A
M
R
Y
Site 80
Y595
S
I
Q
Q
A
M
R
Y
L
R
S
Q
C
L
D
Site 81
S598
Q
A
M
R
Y
L
R
S
Q
C
L
D
Q
V
G
Site 82
S610
Q
V
G
I
F
R
K
S
G
V
K
S
R
I
Q
Site 83
S614
F
R
K
S
G
V
K
S
R
I
Q
N
L
R
Q
Site 84
T625
N
L
R
Q
M
N
E
T
S
P
D
N
V
C
Y
Site 85
S626
L
R
Q
M
N
E
T
S
P
D
N
V
C
Y
E
Site 86
Y632
T
S
P
D
N
V
C
Y
E
G
Q
S
A
Y
D
Site 87
Y647
V
A
D
L
L
K
Q
Y
F
R
D
L
P
E
P
Site 88
T657
D
L
P
E
P
I
F
T
S
K
L
T
T
T
F
Site 89
T697
E
N
R
E
V
L
Q
T
L
L
Y
F
L
S
D
Site 90
S707
Y
F
L
S
D
I
A
S
A
E
E
N
Q
M
T
Site 91
T714
S
A
E
E
N
Q
M
T
A
G
N
L
A
V
C
Site 92
S732
S
I
F
H
L
N
V
S
K
K
D
S
P
S
P
Site 93
S736
L
N
V
S
K
K
D
S
P
S
P
R
I
K
S
Site 94
S738
V
S
K
K
D
S
P
S
P
R
I
K
S
K
R
Site 95
S743
S
P
S
P
R
I
K
S
K
R
S
L
I
G
R
Site 96
S746
P
R
I
K
S
K
R
S
L
I
G
R
P
G
P
Site 97
S757
R
P
G
P
R
D
L
S
D
N
M
A
A
T
Q
Site 98
S771
Q
G
L
S
H
M
I
S
D
C
K
K
L
F
Q
Site 99
S792
L
Q
L
C
S
S
Y
S
A
A
E
L
S
P
P
Site 100
S797
S
Y
S
A
A
E
L
S
P
P
G
P
A
L
A
Site 101
Y819
A
G
V
S
L
S
L
Y
M
E
E
N
I
Q
D
Site 102
S840
E
R
F
K
G
W
M
S
V
P
G
P
Q
H
T
Site 103
S866
P
L
R
L
W
K
A
S
T
E
V
A
A
P
P
Site 104
Y909
P
G
V
E
L
Y
H
Y
V
T
D
S
M
A
P
Site 105
T911
V
E
L
Y
H
Y
V
T
D
S
M
A
P
H
P
Site 106
S930
V
V
L
R
M
W
R
S
D
L
P
R
G
G
C
Site 107
S941
R
G
G
C
L
L
V
S
Q
S
L
D
P
E
Q
Site 108
S953
P
E
Q
P
V
P
E
S
G
V
R
A
L
M
L
Site 109
Y964
A
L
M
L
T
S
Q
Y
L
M
E
P
C
G
L
Site 110
T977
G
L
G
R
S
R
L
T
H
I
C
R
A
D
L
Site 111
S988
R
A
D
L
R
G
R
S
P
D
W
Y
N
K
V
Site 112
Y992
R
G
R
S
P
D
W
Y
N
K
V
F
G
H
L
Site 113
S1010
E
V
A
K
I
R
D
S
F
P
T
L
Q
A
A
Site 114
T1013
K
I
R
D
S
F
P
T
L
Q
A
A
G
P
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation