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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CFHR4
Full Name:
Complement factor H-related protein 4
Alias:
Type:
Mass (Da):
37299
Number AA:
331
UniProt ID:
Q92496
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y35
E
I
Q
H
G
G
L
Y
Y
K
S
L
R
R
L
Site 2
S38
H
G
G
L
Y
Y
K
S
L
R
R
L
Y
F
P
Site 3
Y43
Y
K
S
L
R
R
L
Y
F
P
A
A
A
G
Q
Site 4
Y54
A
A
G
Q
S
Y
S
Y
Y
C
D
Q
N
F
V
Site 5
Y55
A
G
Q
S
Y
S
Y
Y
C
D
Q
N
F
V
T
Site 6
T62
Y
C
D
Q
N
F
V
T
P
S
G
S
Y
W
D
Site 7
T81
T
Q
D
G
W
S
P
T
V
P
C
L
R
T
C
Site 8
T87
P
T
V
P
C
L
R
T
C
S
K
S
D
I
E
Site 9
S89
V
P
C
L
R
T
C
S
K
S
D
I
E
I
E
Site 10
S91
C
L
R
T
C
S
K
S
D
I
E
I
E
N
G
Site 11
S101
E
I
E
N
G
F
I
S
E
S
S
S
I
Y
I
Site 12
S103
E
N
G
F
I
S
E
S
S
S
I
Y
I
L
N
Site 13
S105
G
F
I
S
E
S
S
S
I
Y
I
L
N
K
E
Site 14
Y107
I
S
E
S
S
S
I
Y
I
L
N
K
E
I
Q
Site 15
Y115
I
L
N
K
E
I
Q
Y
K
C
K
P
G
Y
A
Site 16
Y121
Q
Y
K
C
K
P
G
Y
A
T
A
D
G
N
S
Site 17
S131
A
D
G
N
S
S
G
S
I
T
C
L
Q
N
G
Site 18
T133
G
N
S
S
G
S
I
T
C
L
Q
N
G
W
S
Site 19
S157
D
M
P
V
F
E
N
S
R
A
K
S
N
G
M
Site 20
S161
F
E
N
S
R
A
K
S
N
G
M
R
F
K
L
Site 21
Y174
K
L
H
D
T
L
D
Y
E
C
Y
D
G
Y
E
Site 22
Y177
D
T
L
D
Y
E
C
Y
D
G
Y
E
I
S
Y
Site 23
Y180
D
Y
E
C
Y
D
G
Y
E
I
S
Y
G
N
T
Site 24
Y184
Y
D
G
Y
E
I
S
Y
G
N
T
T
G
S
I
Site 25
T187
Y
E
I
S
Y
G
N
T
T
G
S
I
V
C
G
Site 26
S190
S
Y
G
N
T
T
G
S
I
V
C
G
E
D
G
Site 27
S208
F
P
T
C
Y
N
S
S
E
K
C
G
P
P
P
Site 28
S218
C
G
P
P
P
P
I
S
N
G
D
T
T
S
F
Site 29
T222
P
P
I
S
N
G
D
T
T
S
F
L
L
K
V
Site 30
Y238
V
P
Q
S
R
V
E
Y
Q
C
Q
S
Y
Y
E
Site 31
Y243
V
E
Y
Q
C
Q
S
Y
Y
E
L
Q
G
S
N
Site 32
Y244
E
Y
Q
C
Q
S
Y
Y
E
L
Q
G
S
N
Y
Site 33
Y251
Y
E
L
Q
G
S
N
Y
V
T
C
S
N
G
E
Site 34
T253
L
Q
G
S
N
Y
V
T
C
S
N
G
E
W
S
Site 35
S255
G
S
N
Y
V
T
C
S
N
G
E
W
S
E
P
Site 36
S287
N
I
Q
L
K
G
K
S
D
I
K
Y
Y
A
K
Site 37
Y291
K
G
K
S
D
I
K
Y
Y
A
K
T
G
D
T
Site 38
Y292
G
K
S
D
I
K
Y
Y
A
K
T
G
D
T
I
Site 39
S315
N
A
N
T
S
V
L
S
F
Q
A
V
C
R
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation