PhosphoNET

           
Protein Info 
   
Short Name:  ROBO4
Full Name:  Roundabout homolog 4
Alias:  Magic roundabout
Type: 
Mass (Da):  107457
Number AA:  1007
UniProt ID:  Q8WZ75
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S3_____MGSGGDSLLG
Site 2S7_MGSGGDSLLGGRGS
Site 3S30MGGMAQDSPPQILVH
Site 4S52GPGPARMSCQASGQP
Site 5S56ARMSCQASGQPPPTI
Site 6T62ASGQPPPTIRWLLNG
Site 7S73LLNGQPLSMVPPDPH
Site 8S106AHDGQALSTDLGVYT
Site 9Y112LSTDLGVYTCEASNR
Site 10T113STDLGVYTCEASNRL
Site 11T122EASNRLGTAVSRGAR
Site 12S125NRLGTAVSRGARLSV
Site 13S131VSRGARLSVAVLRED
Site 14T186ALQPGRHTVSGGSLL
Site 15S188QPGRHTVSGGSLLMA
Site 16S200LMARAEKSDEGTYMC
Site 17T204AEKSDEGTYMCVATN
Site 18Y205EKSDEGTYMCVATNS
Site 19S218NSAGHRESRAARVSI
Site 20S224ESRAARVSIQEPQDY
Site 21Y231SIQEPQDYTEPVELL
Site 22T232IQEPQDYTEPVELLA
Site 23S267PRPAVWLSWKVSGPA
Site 24T288TALFRTQTAPGGQGA
Site 25Y319GLHWGQDYEFKVRPS
Site 26S326YEFKVRPSSGRARGP
Site 27S327EFKVRPSSGRARGPD
Site 28S335GRARGPDSNVLLLRL
Site 29S348RLPEKVPSAPPQEVT
Site 30T355SAPPQEVTLKPGNGT
Site 31Y382HNGIIRGYQVWSLGN
Site 32S386IRGYQVWSLGNTSLP
Site 33T390QVWSLGNTSLPPANW
Site 34S391VWSLGNTSLPPANWT
Site 35T410QTQLEIATHMPGSYC
Site 36T447EQAMERATQEPSEHG
Site 37T457PSEHGPWTLEQLRAT
Site 38T464TLEQLRATLKRPEVI
Site 39Y504VHLGPGLYRYTSEDA
Site 40Y506LGPGLYRYTSEDAIL
Site 41T507GPGLYRYTSEDAILK
Site 42S508PGLYRYTSEDAILKH
Site 43S520LKHRMDHSDSQWLAD
Site 44T528DSQWLADTWRSTSGS
Site 45S531WLADTWRSTSGSRDL
Site 46T532LADTWRSTSGSRDLS
Site 47S533ADTWRSTSGSRDLSS
Site 48S535TWRSTSGSRDLSSSS
Site 49S539TSGSRDLSSSSSLSS
Site 50S540SGSRDLSSSSSLSSR
Site 51S541GSRDLSSSSSLSSRL
Site 52S542SRDLSSSSSLSSRLG
Site 53S543RDLSSSSSLSSRLGA
Site 54S545LSSSSSLSSRLGADA
Site 55S546SSSSSLSSRLGADAR
Site 56S561DPLDCRRSLLSWDSR
Site 57S564DCRRSLLSWDSRSPG
Site 58S567RSLLSWDSRSPGVPL
Site 59S569LLSWDSRSPGVPLLP
Site 60S584DTSTFYGSLIAELPS
Site 61S592LIAELPSSTPARPSP
Site 62T593IAELPSSTPARPSPQ
Site 63S598SSTPARPSPQVPAVR
Site 64S615PPQLAQLSSPCSSSD
Site 65S616PQLAQLSSPCSSSDS
Site 66S619AQLSSPCSSSDSLCS
Site 67S620QLSSPCSSSDSLCSR
Site 68S621LSSPCSSSDSLCSRR
Site 69S623SPCSSSDSLCSRRGL
Site 70S626SSSDSLCSRRGLSSP
Site 71S631LCSRRGLSSPRLSLA
Site 72S632CSRRGLSSPRLSLAP
Site 73S636GLSSPRLSLAPAEAW
Site 74S656QELQHANSSPLLRGS
Site 75S657ELQHANSSPLLRGSH
Site 76S663SSPLLRGSHSLELRA
Site 77S665PLLRGSHSLELRACE
Site 78S678CELGNRGSKNLSQSP
Site 79S682NRGSKNLSQSPGAVP
Site 80S684GSKNLSQSPGAVPQA
Site 81S706GPKLLSSSNELVTRH
Site 82T711SSSNELVTRHLPPAP
Site 83T724APLFPHETPPTQSQQ
Site 84T727FPHETPPTQSQQTQP
Site 85S729HETPPTQSQQTQPPV
Site 86S758IPILSPCSPPSPQAS
Site 87S761LSPCSPPSPQASSLS
Site 88S765SPPSPQASSLSGPSP
Site 89S766PPSPQASSLSGPSPA
Site 90S768SPQASSLSGPSPASS
Site 91S771ASSLSGPSPASSRLS
Site 92S774LSGPSPASSRLSSSS
Site 93S775SGPSPASSRLSSSSL
Site 94S778SPASSRLSSSSLSSL
Site 95S779PASSRLSSSSLSSLG
Site 96S780ASSRLSSSSLSSLGE
Site 97S781SSRLSSSSLSSLGED
Site 98S783RLSSSSLSSLGEDQD
Site 99S784LSSSSLSSLGEDQDS
Site 100S791SLGEDQDSVLTPEEV
Site 101T794EDQDSVLTPEEVALC
Site 102S805VALCLELSEGEETPR
Site 103T810ELSEGEETPRNSVSP
Site 104S814GEETPRNSVSPMPRA
Site 105S816ETPRNSVSPMPRAPS
Site 106S823SPMPRAPSPPTTYGY
Site 107T826PRAPSPPTTYGYISV
Site 108T827RAPSPPTTYGYISVP
Site 109Y828APSPPTTYGYISVPT
Site 110Y830SPPTTYGYISVPTAS
Site 111S832PTTYGYISVPTASEF
Site 112T865CPPRPCLTPTPSEGS
Site 113T867PRPCLTPTPSEGSLA
Site 114S869PCLTPTPSEGSLANG
Site 115S872TPTPSEGSLANGWGS
Site 116S881ANGWGSASEDNAASA
Site 117S887ASEDNAASARASLVS
Site 118S891NAASARASLVSSSDG
Site 119S894SARASLVSSSDGSFL
Site 120S895ARASLVSSSDGSFLA
Site 121S896RASLVSSSDGSFLAD
Site 122S934DCVFIDASSPPSPRD
Site 123S935CVFIDASSPPSPRDE
Site 124S938IDASSPPSPRDEIFL
Site 125T946PRDEIFLTPNLSLPL
Site 126T969EDMEVSHTQRLGRGM
Site 127S983MPPWPPDSQISSQRS
Site 128S986WPPDSQISSQRSQLH
Site 129S987PPDSQISSQRSQLHC
Site 130S990SQISSQRSQLHCRMP
Site 131S1002RMPKAGASPVDYS__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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