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Updated November 2019
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Protein Info
Short Name:
ZCCHC14
Full Name:
Zinc finger CCHC domain-containing protein 14
Alias:
BDG29; BDG-29; MGC14139; ZCH14; Zinc finger CCHC domain containing protein 14; Zinc finger, CCHC domain containing 14
Type:
Unknown function
Mass (Da):
100040
Number AA:
UniProt ID:
Q8WYQ9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0035091
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007154
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
A
S
N
H
P
A
F
S
F
Site 2
S9
A
S
N
H
P
A
F
S
F
H
Q
K
Q
V
L
Site 3
T21
Q
V
L
R
Q
E
L
T
Q
I
Q
S
S
L
N
Site 4
S25
Q
E
L
T
Q
I
Q
S
S
L
N
G
G
G
G
Site 5
S26
E
L
T
Q
I
Q
S
S
L
N
G
G
G
G
H
Site 6
T55
C
P
A
C
H
K
I
T
P
R
T
E
A
P
V
Site 7
T58
C
H
K
I
T
P
R
T
E
A
P
V
S
S
V
Site 8
S63
P
R
T
E
A
P
V
S
S
V
S
N
S
L
E
Site 9
S64
R
T
E
A
P
V
S
S
V
S
N
S
L
E
N
Site 10
S66
E
A
P
V
S
S
V
S
N
S
L
E
N
A
L
Site 11
S68
P
V
S
S
V
S
N
S
L
E
N
A
L
H
T
Site 12
S79
A
L
H
T
S
A
H
S
T
E
E
S
L
P
K
Site 13
T80
L
H
T
S
A
H
S
T
E
E
S
L
P
K
R
Site 14
S83
S
A
H
S
T
E
E
S
L
P
K
R
P
L
G
Site 15
S96
L
G
K
H
S
K
V
S
V
E
K
I
D
L
K
Site 16
S106
K
I
D
L
K
G
L
S
H
T
K
N
D
R
N
Site 17
S117
N
D
R
N
V
E
C
S
F
E
V
L
W
S
D
Site 18
S125
F
E
V
L
W
S
D
S
S
I
T
S
V
T
K
Site 19
S126
E
V
L
W
S
D
S
S
I
T
S
V
T
K
S
Site 20
S129
W
S
D
S
S
I
T
S
V
T
K
S
S
S
E
Site 21
T131
D
S
S
I
T
S
V
T
K
S
S
S
E
V
T
Site 22
S133
S
I
T
S
V
T
K
S
S
S
E
V
T
E
F
Site 23
S135
T
S
V
T
K
S
S
S
E
V
T
E
F
I
S
Site 24
T138
T
K
S
S
S
E
V
T
E
F
I
S
K
L
C
Site 25
Y148
I
S
K
L
C
Q
L
Y
P
E
E
N
L
E
K
Site 26
Y167
L
A
G
P
D
A
F
Y
V
E
R
N
H
V
D
Site 27
S177
R
N
H
V
D
L
D
S
G
L
R
Y
L
A
S
Site 28
Y181
D
L
D
S
G
L
R
Y
L
A
S
L
P
S
H
Site 29
S187
R
Y
L
A
S
L
P
S
H
V
L
K
N
D
H
Site 30
S200
D
H
V
R
R
F
L
S
T
S
S
P
P
Q
Q
Site 31
T201
H
V
R
R
F
L
S
T
S
S
P
P
Q
Q
L
Site 32
S202
V
R
R
F
L
S
T
S
S
P
P
Q
Q
L
Q
Site 33
S203
R
R
F
L
S
T
S
S
P
P
Q
Q
L
Q
S
Site 34
S210
S
P
P
Q
Q
L
Q
S
P
S
P
G
N
P
S
Site 35
S212
P
Q
Q
L
Q
S
P
S
P
G
N
P
S
L
S
Site 36
S217
S
P
S
P
G
N
P
S
L
S
K
V
G
T
V
Site 37
S219
S
P
G
N
P
S
L
S
K
V
G
T
V
M
G
Site 38
S241
G
V
A
G
I
P
S
S
Q
S
G
A
Q
H
H
Site 39
S243
A
G
I
P
S
S
Q
S
G
A
Q
H
H
G
Q
Site 40
S255
H
G
Q
H
P
A
G
S
A
A
P
L
P
H
C
Site 41
S263
A
A
P
L
P
H
C
S
H
A
G
S
A
G
S
Site 42
S267
P
H
C
S
H
A
G
S
A
G
S
A
L
A
Y
Site 43
Y274
S
A
G
S
A
L
A
Y
R
T
Q
M
D
T
S
Site 44
T280
A
Y
R
T
Q
M
D
T
S
P
A
I
L
M
P
Site 45
S281
Y
R
T
Q
M
D
T
S
P
A
I
L
M
P
S
Site 46
S288
S
P
A
I
L
M
P
S
S
L
Q
T
P
Q
T
Site 47
S289
P
A
I
L
M
P
S
S
L
Q
T
P
Q
T
Q
Site 48
T292
L
M
P
S
S
L
Q
T
P
Q
T
Q
E
Q
N
Site 49
T295
S
S
L
Q
T
P
Q
T
Q
E
Q
N
G
I
L
Site 50
Y313
R
K
L
R
L
H
K
Y
Y
P
V
F
K
Q
L
Site 51
Y314
K
L
R
L
H
K
Y
Y
P
V
F
K
Q
L
S
Site 52
S327
L
S
M
E
K
F
L
S
L
T
E
E
D
L
N
Site 53
S338
E
D
L
N
K
F
E
S
L
T
M
G
A
K
K
Site 54
S358
L
E
L
E
K
E
K
S
E
R
R
C
L
N
P
Site 55
S366
E
R
R
C
L
N
P
S
A
P
P
L
V
T
S
Site 56
T382
G
V
A
R
V
P
P
T
S
H
V
G
P
V
Q
Site 57
S383
V
A
R
V
P
P
T
S
H
V
G
P
V
Q
S
Site 58
S390
S
H
V
G
P
V
Q
S
G
R
G
S
H
A
A
Site 59
S394
P
V
Q
S
G
R
G
S
H
A
A
E
L
R
V
Site 60
S415
H
Q
L
P
R
E
G
S
S
S
E
Y
S
S
S
Site 61
S416
Q
L
P
R
E
G
S
S
S
E
Y
S
S
S
S
Site 62
S417
L
P
R
E
G
S
S
S
E
Y
S
S
S
S
S
Site 63
Y419
R
E
G
S
S
S
E
Y
S
S
S
S
S
S
P
Site 64
S420
E
G
S
S
S
E
Y
S
S
S
S
S
S
P
M
Site 65
S421
G
S
S
S
E
Y
S
S
S
S
S
S
P
M
G
Site 66
S422
S
S
S
E
Y
S
S
S
S
S
S
P
M
G
V
Site 67
S423
S
S
E
Y
S
S
S
S
S
S
P
M
G
V
Q
Site 68
S424
S
E
Y
S
S
S
S
S
S
P
M
G
V
Q
A
Site 69
S425
E
Y
S
S
S
S
S
S
P
M
G
V
Q
A
R
Site 70
S435
G
V
Q
A
R
E
E
S
S
D
S
A
E
E
N
Site 71
S436
V
Q
A
R
E
E
S
S
D
S
A
E
E
N
D
Site 72
S438
A
R
E
E
S
S
D
S
A
E
E
N
D
R
R
Site 73
S453
V
E
I
H
L
E
S
S
D
K
E
K
P
V
M
Site 74
S467
M
L
L
N
H
F
T
S
S
S
A
R
P
T
A
Site 75
S469
L
N
H
F
T
S
S
S
A
R
P
T
A
Q
V
Site 76
T473
T
S
S
S
A
R
P
T
A
Q
V
L
P
V
Q
Site 77
S484
L
P
V
Q
N
E
A
S
S
N
P
S
G
H
H
Site 78
S485
P
V
Q
N
E
A
S
S
N
P
S
G
H
H
P
Site 79
S488
N
E
A
S
S
N
P
S
G
H
H
P
L
P
P
Site 80
S520
V
H
K
P
E
R
G
S
A
D
M
K
L
L
S
Site 81
S532
L
L
S
S
S
V
H
S
L
L
S
L
E
E
R
Site 82
S535
S
S
V
H
S
L
L
S
L
E
E
R
N
K
G
Site 83
S543
L
E
E
R
N
K
G
S
G
P
R
S
S
M
K
Site 84
S547
N
K
G
S
G
P
R
S
S
M
K
V
D
K
S
Site 85
S548
K
G
S
G
P
R
S
S
M
K
V
D
K
S
F
Site 86
S554
S
S
M
K
V
D
K
S
F
G
S
A
M
M
D
Site 87
S566
M
M
D
V
L
P
A
S
A
P
H
Q
P
V
Q
Site 88
S576
H
Q
P
V
Q
V
L
S
G
L
S
E
S
S
S
Site 89
S579
V
Q
V
L
S
G
L
S
E
S
S
S
M
S
P
Site 90
S583
S
G
L
S
E
S
S
S
M
S
P
T
V
S
F
Site 91
S585
L
S
E
S
S
S
M
S
P
T
V
S
F
G
P
Site 92
T587
E
S
S
S
M
S
P
T
V
S
F
G
P
R
T
Site 93
S589
S
S
M
S
P
T
V
S
F
G
P
R
T
K
V
Site 94
T594
T
V
S
F
G
P
R
T
K
V
V
H
A
S
T
Site 95
T601
T
K
V
V
H
A
S
T
L
D
R
V
L
K
T
Site 96
T623
V
E
T
S
T
A
A
T
G
T
P
S
T
V
L
Site 97
T628
A
A
T
G
T
P
S
T
V
L
H
A
A
R
P
Site 98
S649
S
S
S
V
P
A
D
S
A
I
S
G
Q
T
S
Site 99
S652
V
P
A
D
S
A
I
S
G
Q
T
S
C
P
N
Site 100
S656
S
A
I
S
G
Q
T
S
C
P
N
N
V
Q
I
Site 101
T678
N
P
R
T
A
L
Y
T
A
N
T
K
V
A
F
Site 102
S704
Q
G
G
F
C
A
N
S
N
T
A
S
P
S
S
Site 103
T706
G
F
C
A
N
S
N
T
A
S
P
S
S
H
P
Site 104
S708
C
A
N
S
N
T
A
S
P
S
S
H
P
S
T
Site 105
S710
N
S
N
T
A
S
P
S
S
H
P
S
T
S
F
Site 106
S711
S
N
T
A
S
P
S
S
H
P
S
T
S
F
A
Site 107
S714
A
S
P
S
S
H
P
S
T
S
F
A
N
M
A
Site 108
T715
S
P
S
S
H
P
S
T
S
F
A
N
M
A
T
Site 109
S716
P
S
S
H
P
S
T
S
F
A
N
M
A
T
L
Site 110
S725
A
N
M
A
T
L
P
S
C
P
A
P
S
S
S
Site 111
S730
L
P
S
C
P
A
P
S
S
S
P
A
L
S
S
Site 112
S731
P
S
C
P
A
P
S
S
S
P
A
L
S
S
V
Site 113
S732
S
C
P
A
P
S
S
S
P
A
L
S
S
V
P
Site 114
S736
P
S
S
S
P
A
L
S
S
V
P
E
S
S
F
Site 115
S737
S
S
S
P
A
L
S
S
V
P
E
S
S
F
Y
Site 116
S741
A
L
S
S
V
P
E
S
S
F
Y
S
S
S
G
Site 117
S742
L
S
S
V
P
E
S
S
F
Y
S
S
S
G
G
Site 118
Y744
S
V
P
E
S
S
F
Y
S
S
S
G
G
G
G
Site 119
S745
V
P
E
S
S
F
Y
S
S
S
G
G
G
G
S
Site 120
S746
P
E
S
S
F
Y
S
S
S
G
G
G
G
S
T
Site 121
S747
E
S
S
F
Y
S
S
S
G
G
G
G
S
T
G
Site 122
S752
S
S
S
G
G
G
G
S
T
G
N
I
P
A
S
Site 123
S796
T
S
C
G
C
S
G
S
C
G
S
S
G
L
T
Site 124
S800
C
S
G
S
C
G
S
S
G
L
T
V
S
Y
A
Site 125
S805
G
S
S
G
L
T
V
S
Y
A
N
Y
F
Q
H
Site 126
Y806
S
S
G
L
T
V
S
Y
A
N
Y
F
Q
H
P
Site 127
Y809
L
T
V
S
Y
A
N
Y
F
Q
H
P
F
S
G
Site 128
S833
P
F
S
P
M
C
S
S
G
Y
V
S
A
Q
Q
Site 129
Y835
S
P
M
C
S
S
G
Y
V
S
A
Q
Q
Y
G
Site 130
S837
M
C
S
S
G
Y
V
S
A
Q
Q
Y
G
G
G
Site 131
Y841
G
Y
V
S
A
Q
Q
Y
G
G
G
S
T
F
P
Site 132
T846
Q
Q
Y
G
G
G
S
T
F
P
V
V
H
A
P
Site 133
Y854
F
P
V
V
H
A
P
Y
S
S
S
G
T
P
D
Site 134
S855
P
V
V
H
A
P
Y
S
S
S
G
T
P
D
P
Site 135
S857
V
H
A
P
Y
S
S
S
G
T
P
D
P
V
L
Site 136
T859
A
P
Y
S
S
S
G
T
P
D
P
V
L
S
G
Site 137
S894
Q
T
Q
G
L
V
G
S
S
N
G
S
S
H
K
Site 138
S898
L
V
G
S
S
N
G
S
S
H
K
K
S
G
N
Site 139
S899
V
G
S
S
N
G
S
S
H
K
K
S
G
N
L
Site 140
S903
N
G
S
S
H
K
K
S
G
N
L
S
C
Y
N
Site 141
Y909
K
S
G
N
L
S
C
Y
N
C
G
A
T
G
H
Site 142
T933
M
D
F
N
R
P
G
T
F
R
L
K
Y
A
P
Site 143
Y938
P
G
T
F
R
L
K
Y
A
P
P
A
E
S
L
Site 144
S944
K
Y
A
P
P
A
E
S
L
D
S
T
D
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation