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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ATG4A
Full Name:
Cysteine protease ATG4A
Alias:
AUT-like 2 cysteine endopeptidase;Autophagin-2;Autophagy-related cysteine endopeptidase 2;Autophagy-related protein 4 homolog A
Type:
Mass (Da):
45378
Number AA:
398
UniProt ID:
Q8WYN0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
ATG4 autophagy related 4 homologue A (S. cerevisiae) pan-specific antibody AB-NN373-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN373-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
E
S
V
L
S
K
Y
E
D
Q
I
T
I
F
Site 2
T13
S
K
Y
E
D
Q
I
T
I
F
T
D
Y
L
E
Site 3
Y18
Q
I
T
I
F
T
D
Y
L
E
E
Y
P
D
T
Site 4
Y22
F
T
D
Y
L
E
E
Y
P
D
T
D
E
L
V
Site 5
T25
Y
L
E
E
Y
P
D
T
D
E
L
V
W
I
L
Site 6
T40
G
K
Q
H
L
L
K
T
E
K
S
K
L
L
S
Site 7
S43
H
L
L
K
T
E
K
S
K
L
L
S
D
I
S
Site 8
S47
T
E
K
S
K
L
L
S
D
I
S
A
R
L
W
Site 9
T56
I
S
A
R
L
W
F
T
Y
R
R
K
F
S
P
Site 10
Y57
S
A
R
L
W
F
T
Y
R
R
K
F
S
P
I
Site 11
S62
F
T
Y
R
R
K
F
S
P
I
G
G
T
G
P
Site 12
T67
K
F
S
P
I
G
G
T
G
P
S
S
D
A
G
Site 13
S70
P
I
G
G
T
G
P
S
S
D
A
G
W
G
C
Site 14
S71
I
G
G
T
G
P
S
S
D
A
G
W
G
C
M
Site 15
S100
R
H
L
G
R
D
W
S
W
E
K
Q
K
E
Q
Site 16
Y111
Q
K
E
Q
P
K
E
Y
Q
R
I
L
Q
C
F
Site 17
S141
M
G
V
G
E
G
K
S
I
G
E
W
F
G
P
Site 18
T150
G
E
W
F
G
P
N
T
V
A
Q
V
L
K
K
Site 19
Y170
E
W
N
S
L
A
V
Y
V
S
M
D
N
T
V
Site 20
S192
M
C
R
V
L
P
L
S
A
D
T
A
G
D
R
Site 21
S203
A
G
D
R
P
P
D
S
L
T
A
S
N
Q
S
Site 22
T205
D
R
P
P
D
S
L
T
A
S
N
Q
S
K
G
Site 23
S207
P
P
D
S
L
T
A
S
N
Q
S
K
G
T
S
Site 24
S214
S
N
Q
S
K
G
T
S
A
Y
C
S
A
W
K
Site 25
Y240
I
N
Q
I
N
P
V
Y
V
D
A
F
K
E
C
Site 26
S253
E
C
F
K
M
P
Q
S
L
G
A
L
G
G
K
Site 27
Y265
G
G
K
P
N
N
A
Y
Y
F
I
G
F
L
G
Site 28
Y266
G
K
P
N
N
A
Y
Y
F
I
G
F
L
G
D
Site 29
T285
L
D
P
H
T
T
Q
T
F
V
D
T
E
E
N
Site 30
T289
T
T
Q
T
F
V
D
T
E
E
N
G
T
V
N
Site 31
T294
V
D
T
E
E
N
G
T
V
N
D
Q
T
F
H
Site 32
T373
A
K
P
E
V
T
T
T
G
A
E
F
I
D
S
Site 33
S380
T
G
A
E
F
I
D
S
T
E
Q
L
E
E
F
Site 34
T381
G
A
E
F
I
D
S
T
E
Q
L
E
E
F
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation