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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARNTL2
Full Name:
Aryl hydrocarbon receptor nuclear translocator-like protein 2
Alias:
Basic-helix-loop-helix-PAS protein MOP9;Brain and muscle ARNT-like 2;CYCLE-like factor;Class E basic helix-loop-helix protein 6;Member of PAS protein 9;PAS domain-containing protein 9
Type:
Mass (Da):
70887
Number AA:
636
UniProt ID:
Q8WYA1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S30
P
V
V
S
S
R
V
S
P
G
T
R
P
T
A
Site 2
T33
S
S
R
V
S
P
G
T
R
P
T
A
M
G
S
Site 3
T36
V
S
P
G
T
R
P
T
A
M
G
S
F
S
S
Site 4
S40
T
R
P
T
A
M
G
S
F
S
S
H
M
T
E
Site 5
S42
P
T
A
M
G
S
F
S
S
H
M
T
E
F
P
Site 6
S43
T
A
M
G
S
F
S
S
H
M
T
E
F
P
R
Site 7
T46
G
S
F
S
S
H
M
T
E
F
P
R
K
R
K
Site 8
S55
F
P
R
K
R
K
G
S
D
S
D
P
S
Q
S
Site 9
S57
R
K
R
K
G
S
D
S
D
P
S
Q
S
G
I
Site 10
S60
K
G
S
D
S
D
P
S
Q
S
G
I
M
T
E
Site 11
T66
P
S
Q
S
G
I
M
T
E
K
V
V
E
K
L
Site 12
S74
E
K
V
V
E
K
L
S
Q
N
P
L
T
Y
L
Site 13
T79
K
L
S
Q
N
P
L
T
Y
L
L
S
T
R
I
Site 14
S89
L
S
T
R
I
E
I
S
A
S
S
G
S
R
V
Site 15
S91
T
R
I
E
I
S
A
S
S
G
S
R
V
E
D
Site 16
S92
R
I
E
I
S
A
S
S
G
S
R
V
E
D
G
Site 17
S113
K
A
F
R
E
A
H
S
Q
T
E
K
R
R
R
Site 18
T148
A
R
K
L
D
K
L
T
V
L
R
M
A
V
Q
Site 19
S159
M
A
V
Q
H
L
R
S
L
K
G
L
T
N
S
Site 20
T164
L
R
S
L
K
G
L
T
N
S
Y
V
G
S
N
Site 21
S166
S
L
K
G
L
T
N
S
Y
V
G
S
N
Y
R
Site 22
Y167
L
K
G
L
T
N
S
Y
V
G
S
N
Y
R
P
Site 23
S170
L
T
N
S
Y
V
G
S
N
Y
R
P
S
F
L
Site 24
Y172
N
S
Y
V
G
S
N
Y
R
P
S
F
L
Q
D
Site 25
S175
V
G
S
N
Y
R
P
S
F
L
Q
D
N
E
L
Site 26
S208
R
G
K
I
L
F
V
S
K
S
V
S
K
I
L
Site 27
S210
K
I
L
F
V
S
K
S
V
S
K
I
L
N
Y
Site 28
S212
L
F
V
S
K
S
V
S
K
I
L
N
Y
D
Q
Site 29
Y217
S
V
S
K
I
L
N
Y
D
Q
A
S
L
T
G
Site 30
S226
Q
A
S
L
T
G
Q
S
L
F
D
F
L
H
P
Site 31
S244
A
K
V
K
E
Q
L
S
S
F
D
I
S
P
R
Site 32
S245
K
V
K
E
Q
L
S
S
F
D
I
S
P
R
E
Site 33
S249
Q
L
S
S
F
D
I
S
P
R
E
K
L
I
D
Site 34
T259
E
K
L
I
D
A
K
T
G
L
Q
V
H
S
N
Site 35
T272
S
N
L
H
A
G
R
T
R
V
Y
S
G
S
R
Site 36
Y275
H
A
G
R
T
R
V
Y
S
G
S
R
R
S
F
Site 37
S276
A
G
R
T
R
V
Y
S
G
S
R
R
S
F
F
Site 38
S278
R
T
R
V
Y
S
G
S
R
R
S
F
F
C
R
Site 39
S281
V
Y
S
G
S
R
R
S
F
F
C
R
I
K
S
Site 40
S288
S
F
F
C
R
I
K
S
C
K
I
S
V
K
E
Site 41
S292
R
I
K
S
C
K
I
S
V
K
E
E
H
G
C
Site 42
S303
E
H
G
C
L
P
N
S
K
K
K
E
H
R
K
Site 43
Y312
K
K
E
H
R
K
F
Y
T
I
H
C
T
G
Y
Site 44
S336
G
M
E
E
E
R
N
S
K
K
D
N
S
N
F
Site 45
S341
R
N
S
K
K
D
N
S
N
F
T
C
L
V
A
Site 46
Y355
A
I
G
R
L
Q
P
Y
I
V
P
Q
N
S
G
Site 47
Y383
A
V
N
G
K
F
V
Y
V
D
Q
R
A
T
A
Site 48
T402
L
P
Q
E
L
L
G
T
S
C
Y
E
Y
F
H
Site 49
Y405
E
L
L
G
T
S
C
Y
E
Y
F
H
Q
D
D
Site 50
Y407
L
G
T
S
C
Y
E
Y
F
H
Q
D
D
H
N
Site 51
T432
Q
S
K
E
K
I
L
T
D
S
Y
K
F
R
A
Site 52
S434
K
E
K
I
L
T
D
S
Y
K
F
R
A
K
D
Site 53
Y435
E
K
I
L
T
D
S
Y
K
F
R
A
K
D
G
Site 54
S443
K
F
R
A
K
D
G
S
F
V
T
L
K
S
Q
Site 55
S449
G
S
F
V
T
L
K
S
Q
W
F
S
F
T
N
Site 56
S482
H
S
E
P
G
E
A
S
F
L
P
C
S
S
Q
Site 57
S487
E
A
S
F
L
P
C
S
S
Q
S
S
E
E
S
Site 58
S488
A
S
F
L
P
C
S
S
Q
S
S
E
E
S
S
Site 59
S490
F
L
P
C
S
S
Q
S
S
E
E
S
S
R
Q
Site 60
S491
L
P
C
S
S
Q
S
S
E
E
S
S
R
Q
S
Site 61
S494
S
S
Q
S
S
E
E
S
S
R
Q
S
C
M
S
Site 62
S495
S
Q
S
S
E
E
S
S
R
Q
S
C
M
S
V
Site 63
S498
S
E
E
S
S
R
Q
S
C
M
S
V
P
G
M
Site 64
S501
S
S
R
Q
S
C
M
S
V
P
G
M
S
T
G
Site 65
S532
L
D
L
Q
R
L
Q
S
S
S
Y
L
D
D
S
Site 66
S534
L
Q
R
L
Q
S
S
S
Y
L
D
D
S
S
P
Site 67
Y535
Q
R
L
Q
S
S
S
Y
L
D
D
S
S
P
T
Site 68
S539
S
S
S
Y
L
D
D
S
S
P
T
G
L
M
K
Site 69
S540
S
S
Y
L
D
D
S
S
P
T
G
L
M
K
D
Site 70
T548
P
T
G
L
M
K
D
T
H
T
V
N
C
R
S
Site 71
T550
G
L
M
K
D
T
H
T
V
N
C
R
S
M
S
Site 72
S557
T
V
N
C
R
S
M
S
N
K
E
L
F
P
P
Site 73
S565
N
K
E
L
F
P
P
S
P
S
E
M
G
E
L
Site 74
S567
E
L
F
P
P
S
P
S
E
M
G
E
L
E
A
Site 75
T575
E
M
G
E
L
E
A
T
R
Q
N
Q
S
T
V
Site 76
T581
A
T
R
Q
N
Q
S
T
V
A
V
H
S
H
E
Site 77
S586
Q
S
T
V
A
V
H
S
H
E
P
L
L
S
D
Site 78
S592
H
S
H
E
P
L
L
S
D
G
A
Q
L
D
F
Site 79
S630
L
G
D
P
G
D
F
S
D
I
Q
W
T
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation