PhosphoNET

           
Protein Info 
   
Short Name:  DEDD2
Full Name:  DNA-binding death effector domain-containing protein 2
Alias:  DED-containing protein FLAME-3;FADD-like anti-apoptotic molecule 3
Type: 
Mass (Da):  36179
Number AA:  326
UniProt ID:  Q8WXF8
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T7_MALSGSTPAPCWEE
Site 2Y20EEDECLDYYGMLSLH
Site 3Y21EDECLDYYGMLSLHR
Site 4S81RRGQCDESNLRLLGQ
Site 5S111RKRRRPVSPERYSYG
Site 6Y115RPVSPERYSYGTSSS
Site 7S116PVSPERYSYGTSSSS
Site 8Y117VSPERYSYGTSSSSK
Site 9T119PERYSYGTSSSSKRT
Site 10S120ERYSYGTSSSSKRTE
Site 11S121RYSYGTSSSSKRTEG
Site 12S122YSYGTSSSSKRTEGS
Site 13S123SYGTSSSSKRTEGSC
Site 14T126TSSSSKRTEGSCRRR
Site 15S129SSKRTEGSCRRRRQS
Site 16S136SCRRRRQSSSSANSQ
Site 17S137CRRRRQSSSSANSQQ
Site 18S138RRRRQSSSSANSQQG
Site 19S139RRRQSSSSANSQQGQ
Site 20S142QSSSSANSQQGQWET
Site 21T149SQQGQWETGSPPTKR
Site 22S151QGQWETGSPPTKRQR
Site 23S160PTKRQRRSRGRPSGG
Site 24S165RRSRGRPSGGARRRR
Site 25S183PAAPQQQSEPARPSS
Site 26S189QSEPARPSSEGKVTC
Site 27S190SEPARPSSEGKVTCD
Site 28T195PSSEGKVTCDIRLRV
Site 29Y206RLRVRAEYCEHGPAL
Site 30Y258IKFSELSYLDAFWGD
Site 31S298EAVRLLVSVDEADYE
Site 32Y304VSVDEADYEAGRRRL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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