KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZNF606
Full Name:
Zinc finger protein 606
Alias:
Zinc finger 328; ZN606; ZNF328
Type:
Mass (Da):
91812
Number AA:
792
UniProt ID:
Q8WXB4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
T
D
Q
S
W
G
M
T
A
V
D
P
W
A
S
Site 2
S43
P
A
W
H
V
E
G
S
L
E
E
G
R
R
A
Site 3
T51
L
E
E
G
R
R
A
T
G
L
P
A
A
Q
V
Site 4
T72
K
D
V
A
V
D
F
T
Q
E
E
W
G
Q
L
Site 5
Y87
D
L
V
Q
R
T
L
Y
R
D
V
M
L
E
T
Site 6
S100
E
T
Y
G
H
L
L
S
V
G
N
Q
I
A
K
Site 7
S122
E
Q
G
E
E
P
W
S
V
E
Q
A
C
P
Q
Site 8
S149
K
A
L
I
P
A
Q
S
I
F
E
E
E
Q
S
Site 9
S156
S
I
F
E
E
E
Q
S
H
G
M
K
L
E
R
Site 10
Y186
C
K
D
Q
L
E
M
Y
H
M
N
Q
S
T
A
Site 11
S206
F
M
Q
K
Q
V
L
S
Q
R
S
S
E
F
C
Site 12
S210
Q
V
L
S
Q
R
S
S
E
F
C
G
L
G
A
Site 13
S228
Q
N
L
N
F
V
P
S
Q
R
V
S
Q
I
E
Site 14
S232
F
V
P
S
Q
R
V
S
Q
I
E
H
F
Y
K
Site 15
Y255
R
C
D
S
A
I
M
Y
A
D
K
V
T
C
E
Site 16
Y266
V
T
C
E
N
N
D
Y
D
K
T
V
Y
Q
S
Site 17
T269
E
N
N
D
Y
D
K
T
V
Y
Q
S
I
Q
P
Site 18
Y271
N
D
Y
D
K
T
V
Y
Q
S
I
Q
P
I
Y
Site 19
Y278
Y
Q
S
I
Q
P
I
Y
P
A
R
I
Q
T
G
Site 20
T284
I
Y
P
A
R
I
Q
T
G
D
N
L
F
K
C
Site 21
T292
G
D
N
L
F
K
C
T
D
A
V
K
S
F
N
Site 22
Y317
I
H
T
G
E
K
L
Y
E
Y
K
E
C
H
Q
Site 23
Y319
T
G
E
K
L
Y
E
Y
K
E
C
H
Q
I
F
Site 24
S331
Q
I
F
N
Q
S
P
S
F
N
E
H
P
R
L
Site 25
Y347
V
G
E
N
Q
Y
N
Y
K
E
Y
E
N
I
F
Site 26
Y350
N
Q
Y
N
Y
K
E
Y
E
N
I
F
Y
F
S
Site 27
Y355
K
E
Y
E
N
I
F
Y
F
S
S
F
M
E
H
Site 28
T367
M
E
H
Q
K
I
G
T
V
E
K
A
Y
K
Y
Site 29
Y372
I
G
T
V
E
K
A
Y
K
Y
N
E
W
E
K
Site 30
Y374
T
V
E
K
A
Y
K
Y
N
E
W
E
K
V
F
Site 31
Y383
E
W
E
K
V
F
G
Y
D
S
F
L
T
Q
H
Site 32
S385
E
K
V
F
G
Y
D
S
F
L
T
Q
H
T
S
Site 33
T388
F
G
Y
D
S
F
L
T
Q
H
T
S
T
Y
T
Site 34
S392
S
F
L
T
Q
H
T
S
T
Y
T
A
E
K
P
Site 35
Y394
L
T
Q
H
T
S
T
Y
T
A
E
K
P
Y
D
Site 36
Y402
T
A
E
K
P
Y
D
Y
N
E
C
G
T
S
F
Site 37
Y428
T
H
T
G
E
K
P
Y
E
C
D
K
C
G
K
Site 38
S441
G
K
V
F
R
N
R
S
A
L
T
K
H
E
R
Site 39
T451
T
K
H
E
R
T
H
T
G
I
K
P
Y
E
C
Site 40
Y456
T
H
T
G
I
K
P
Y
E
C
N
K
C
G
K
Site 41
T479
I
V
H
K
R
I
H
T
G
E
K
P
Y
V
C
Site 42
Y484
I
H
T
G
E
K
P
Y
V
C
N
E
C
G
K
Site 43
T505
H
L
I
G
H
Q
R
T
H
T
G
E
K
P
F
Site 44
T507
I
G
H
Q
R
T
H
T
G
E
K
P
F
E
C
Site 45
T515
G
E
K
P
F
E
C
T
E
C
G
K
S
F
S
Site 46
S520
E
C
T
E
C
G
K
S
F
S
W
S
S
H
L
Site 47
S522
T
E
C
G
K
S
F
S
W
S
S
H
L
I
A
Site 48
S525
G
K
S
F
S
W
S
S
H
L
I
A
H
M
R
Site 49
T535
I
A
H
M
R
M
H
T
G
E
K
P
F
K
C
Site 50
Y552
C
E
K
A
F
R
D
Y
S
A
L
S
K
H
E
Site 51
S553
E
K
A
F
R
D
Y
S
A
L
S
K
H
E
R
Site 52
S556
F
R
D
Y
S
A
L
S
K
H
E
R
T
H
S
Site 53
T561
A
L
S
K
H
E
R
T
H
S
G
A
K
P
Y
Site 54
S563
S
K
H
E
R
T
H
S
G
A
K
P
Y
K
C
Site 55
Y568
T
H
S
G
A
K
P
Y
K
C
T
E
C
G
K
Site 56
T571
G
A
K
P
Y
K
C
T
E
C
G
K
S
F
S
Site 57
S576
K
C
T
E
C
G
K
S
F
S
W
S
S
H
L
Site 58
S581
G
K
S
F
S
W
S
S
H
L
I
A
H
Q
R
Site 59
T589
H
L
I
A
H
Q
R
T
H
T
G
E
K
P
Y
Site 60
T591
I
A
H
Q
R
T
H
T
G
E
K
P
Y
N
C
Site 61
Y596
T
H
T
G
E
K
P
Y
N
C
Q
E
C
G
K
Site 62
S609
G
K
A
F
R
E
R
S
A
L
T
K
H
E
I
Site 63
Y624
I
H
S
G
I
K
P
Y
E
C
N
K
C
G
K
Site 64
T645
H
L
V
R
H
Q
R
T
H
T
G
E
K
P
Y
Site 65
T647
V
R
H
Q
R
T
H
T
G
E
K
P
Y
E
C
Site 66
Y652
T
H
T
G
E
K
P
Y
E
C
N
K
C
G
K
Site 67
S662
N
K
C
G
K
S
F
S
Q
S
C
H
L
V
A
Site 68
T675
V
A
H
R
R
I
H
T
G
E
K
P
Y
K
C
Site 69
T701
H
L
I
A
H
R
R
T
H
T
G
E
K
P
Y
Site 70
T703
I
A
H
R
R
T
H
T
G
E
K
P
Y
R
C
Site 71
Y708
T
H
T
G
E
K
P
Y
R
C
N
E
C
G
K
Site 72
S722
K
A
F
N
E
S
S
S
L
I
V
H
L
R
N
Site 73
T731
I
V
H
L
R
N
H
T
G
E
K
P
Y
K
C
Site 74
S767
G
E
K
R
F
I
C
S
E
C
G
K
A
F
S
Site 75
S774
S
E
C
G
K
A
F
S
G
H
S
A
L
L
Q
Site 76
S787
L
Q
H
Q
R
N
H
S
E
E
K
L
N
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation