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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TTC15
Full Name:
Tetratricopeptide repeat protein 15
Alias:
CGI-87; tetratricopeptide repeat 15; tetratricopeptide repeat domain 15; TPR repeat 15
Type:
Unknown function
Mass (Da):
79375
Number AA:
735
UniProt ID:
Q8WVT3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
D
A
G
G
G
E
E
T
P
A
P
E
A
P
H
Site 2
S45
L
G
G
D
E
F
G
S
E
E
N
E
T
A
S
Site 3
T50
F
G
S
E
E
N
E
T
A
S
E
G
S
S
P
Site 4
S52
S
E
E
N
E
T
A
S
E
G
S
S
P
L
A
Site 5
S56
E
T
A
S
E
G
S
S
P
L
A
D
K
L
N
Site 6
S69
L
N
E
H
M
M
E
S
V
L
I
S
D
S
P
Site 7
S73
M
M
E
S
V
L
I
S
D
S
P
N
S
E
G
Site 8
S75
E
S
V
L
I
S
D
S
P
N
S
E
G
D
A
Site 9
S78
L
I
S
D
S
P
N
S
E
G
D
A
G
D
L
Site 10
T107
P
G
P
E
P
A
G
T
P
S
P
S
G
E
A
Site 11
S109
P
E
P
A
G
T
P
S
P
S
G
E
A
D
G
Site 12
S127
P
E
D
A
A
P
S
S
G
G
A
P
R
Q
D
Site 13
S142
A
A
R
E
V
P
G
S
E
A
A
R
P
E
Q
Site 14
S171
S
Q
R
A
P
P
A
S
G
D
G
F
E
P
Q
Site 15
S182
F
E
P
Q
M
V
K
S
P
S
F
G
G
A
S
Site 16
S184
P
Q
M
V
K
S
P
S
F
G
G
A
S
E
A
Site 17
S189
S
P
S
F
G
G
A
S
E
A
S
A
R
T
P
Site 18
S192
F
G
G
A
S
E
A
S
A
R
T
P
P
Q
V
Site 19
T195
A
S
E
A
S
A
R
T
P
P
Q
V
V
Q
P
Site 20
S203
P
P
Q
V
V
Q
P
S
P
S
L
S
T
F
F
Site 21
S205
Q
V
V
Q
P
S
P
S
L
S
T
F
F
G
D
Site 22
S207
V
Q
P
S
P
S
L
S
T
F
F
G
D
T
A
Site 23
T208
Q
P
S
P
S
L
S
T
F
F
G
D
T
A
A
Site 24
S218
G
D
T
A
A
S
H
S
L
A
S
D
F
F
D
Site 25
S236
T
S
A
F
I
S
V
S
N
P
G
A
G
S
P
Site 26
S242
V
S
N
P
G
A
G
S
P
A
P
A
S
P
P
Site 27
T256
P
P
L
A
V
P
G
T
E
G
R
P
E
P
V
Site 28
S276
Q
A
A
A
P
P
A
S
P
E
P
F
A
H
I
Site 29
S299
D
P
F
A
T
A
L
S
M
S
E
M
D
R
R
Site 30
S301
F
A
T
A
L
S
M
S
E
M
D
R
R
N
D
Site 31
S376
R
Q
V
L
N
A
D
S
V
E
Q
S
F
V
G
Site 32
S380
N
A
D
S
V
E
Q
S
F
V
G
L
K
Q
L
Site 33
S389
V
G
L
K
Q
L
I
S
C
R
N
W
R
A
A
Site 34
T405
D
L
C
G
R
L
L
T
A
H
G
Q
G
Y
G
Site 35
S414
H
G
Q
G
Y
G
K
S
G
L
L
T
S
H
T
Site 36
T418
Y
G
K
S
G
L
L
T
S
H
T
T
D
S
L
Site 37
S419
G
K
S
G
L
L
T
S
H
T
T
D
S
L
Q
Site 38
T421
S
G
L
L
T
S
H
T
T
D
S
L
Q
L
W
Site 39
S424
L
T
S
H
T
T
D
S
L
Q
L
W
F
V
R
Site 40
Y460
N
L
D
Q
P
D
L
Y
Y
E
Y
Y
P
H
V
Site 41
Y461
L
D
Q
P
D
L
Y
Y
E
Y
Y
P
H
V
Y
Site 42
Y463
Q
P
D
L
Y
Y
E
Y
Y
P
H
V
Y
P
G
Site 43
Y464
P
D
L
Y
Y
E
Y
Y
P
H
V
Y
P
G
R
Site 44
Y468
Y
E
Y
Y
P
H
V
Y
P
G
R
R
G
S
M
Site 45
S474
V
Y
P
G
R
R
G
S
M
V
P
F
S
M
R
Site 46
S479
R
G
S
M
V
P
F
S
M
R
I
L
H
A
E
Site 47
Y490
L
H
A
E
L
Q
Q
Y
L
G
N
P
Q
E
S
Site 48
S497
Y
L
G
N
P
Q
E
S
L
D
R
L
H
K
V
Site 49
T506
D
R
L
H
K
V
K
T
V
C
S
K
I
L
A
Site 50
S527
A
E
D
G
G
M
S
S
V
T
Q
E
G
R
Q
Site 51
T529
D
G
G
M
S
S
V
T
Q
E
G
R
Q
A
S
Site 52
S536
T
Q
E
G
R
Q
A
S
I
R
L
W
R
S
R
Site 53
S542
A
S
I
R
L
W
R
S
R
L
G
R
V
M
Y
Site 54
S570
L
A
V
E
A
Y
H
S
V
I
K
Y
Y
P
E
Site 55
Y574
A
Y
H
S
V
I
K
Y
Y
P
E
Q
E
P
Q
Site 56
Y575
Y
H
S
V
I
K
Y
Y
P
E
Q
E
P
Q
L
Site 57
S584
E
Q
E
P
Q
L
L
S
G
I
G
R
I
S
L
Site 58
T598
L
Q
I
G
D
I
K
T
A
E
K
Y
F
Q
D
Site 59
Y602
D
I
K
T
A
E
K
Y
F
Q
D
V
E
K
V
Site 60
T644
A
E
A
H
R
F
F
T
E
I
L
R
M
D
P
Site 61
S673
Y
L
G
K
L
K
D
S
L
R
Q
L
E
A
M
Site 62
Y688
V
Q
Q
D
P
R
H
Y
L
H
E
S
V
L
F
Site 63
S692
P
R
H
Y
L
H
E
S
V
L
F
N
L
T
T
Site 64
T698
E
S
V
L
F
N
L
T
T
M
Y
E
L
E
S
Site 65
Y701
L
F
N
L
T
T
M
Y
E
L
E
S
S
R
S
Site 66
S705
T
T
M
Y
E
L
E
S
S
R
S
M
Q
K
K
Site 67
S706
T
M
Y
E
L
E
S
S
R
S
M
Q
K
K
Q
Site 68
S708
Y
E
L
E
S
S
R
S
M
Q
K
K
Q
A
L
Site 69
S726
V
A
G
K
E
G
D
S
F
N
T
Q
C
L
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation