PhosphoNET

           
Protein Info 
   
Short Name:  MITD1
Full Name:  MIT domain-containing protein 1
Alias: 
Type: 
Mass (Da):  29314
Number AA:  249
UniProt ID:  Q8WV92
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S12GLRQDPQSTAAATVL
Site 2S27KRAVELDSESRYPQA
Site 3S29AVELDSESRYPQALV
Site 4Y31ELDSESRYPQALVCY
Site 5T56LKGTKDNTKRCNLRE
Site 6S66CNLREKISKYMDRAE
Site 7Y68LREKISKYMDRAENI
Site 8Y78RAENIKKYLDQEKED
Site 9Y88QEKEDGKYHKQIKIE
Site 10T99IKIEENATGFSYESL
Site 11Y103ENATGFSYESLFREY
Site 12S105ATGFSYESLFREYLN
Site 13Y110YESLFREYLNETVTE
Site 14T114FREYLNETVTEVWIE
Site 15Y124EVWIEDPYIRHTHQL
Site 16T128EDPYIRHTHQLYNFL
Site 17Y132IRHTHQLYNFLRFCE
Site 18T150KRPCKVKTIHLLTSL
Site 19S156KTIHLLTSLDEGIEQ
Site 20S176GLQEIEESLRSHGVL
Site 21S179EIEESLRSHGVLLEV
Site 22Y188GVLLEVQYSSSIHDR
Site 23S189VLLEVQYSSSIHDRE
Site 24S191LEVQYSSSIHDREIR
Site 25Y213KIGRGLDYFKKPQSR
Site 26S219DYFKKPQSRFSLGYC
Site 27S222KKPQSRFSLGYCDFD
Site 28Y225QSRFSLGYCDFDLRP
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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