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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRIM41
Full Name:
E3 ubiquitin-protein ligase TRIM41
Alias:
RING finger-interacting protein with C kinase;Tripartite motif-containing protein 41
Type:
Mass (Da):
71670
Number AA:
630
UniProt ID:
Q8WV44
International Prot ID:
IPI00414021
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T84
G
A
G
A
G
W
D
T
P
M
R
D
E
D
Y
Site 2
Y91
T
P
M
R
D
E
D
Y
E
G
D
M
E
E
E
Site 3
S110
E
E
G
V
F
W
T
S
G
M
S
R
S
S
W
Site 4
S116
T
S
G
M
S
R
S
S
W
D
N
M
D
Y
V
Site 5
Y122
S
S
W
D
N
M
D
Y
V
W
E
E
E
D
E
Site 6
Y135
D
E
E
E
D
L
D
Y
Y
L
G
D
M
E
E
Site 7
Y136
E
E
E
D
L
D
Y
Y
L
G
D
M
E
E
E
Site 8
T169
E
E
D
L
D
P
V
T
P
L
P
P
P
P
A
Site 9
T182
P
A
P
R
R
C
F
T
C
P
Q
C
R
K
S
Site 10
S189
T
C
P
Q
C
R
K
S
F
P
R
R
S
F
R
Site 11
S194
R
K
S
F
P
R
R
S
F
R
P
N
L
Q
L
Site 12
T214
V
I
R
Q
M
H
P
T
P
G
R
G
S
R
V
Site 13
S219
H
P
T
P
G
R
G
S
R
V
T
D
Q
G
I
Site 14
T222
P
G
R
G
S
R
V
T
D
Q
G
I
C
P
K
Site 15
S259
S
R
S
H
K
Q
H
S
V
V
P
L
E
E
V
Site 16
T300
A
K
E
E
R
R
V
T
E
L
K
S
Q
M
K
Site 17
S304
R
R
V
T
E
L
K
S
Q
M
K
S
E
L
A
Site 18
S308
E
L
K
S
Q
M
K
S
E
L
A
A
V
A
S
Site 19
S315
S
E
L
A
A
V
A
S
E
F
G
R
L
T
R
Site 20
T321
A
S
E
F
G
R
L
T
R
F
L
A
E
E
Q
Site 21
S371
L
A
E
A
Q
E
R
S
Q
Q
G
G
L
R
L
Site 22
T385
L
L
Q
D
I
K
E
T
F
N
R
C
E
E
V
Site 23
S401
L
Q
P
P
E
V
W
S
P
D
P
C
Q
P
H
Site 24
S409
P
D
P
C
Q
P
H
S
H
D
F
L
T
D
A
Site 25
T414
P
H
S
H
D
F
L
T
D
A
I
V
R
K
M
Site 26
T434
Q
A
A
R
V
D
L
T
L
D
P
D
T
A
H
Site 27
T439
D
L
T
L
D
P
D
T
A
H
P
A
L
M
L
Site 28
S447
A
H
P
A
L
M
L
S
P
D
R
R
G
V
R
Site 29
S470
A
D
H
P
K
R
F
S
A
D
C
C
V
L
G
Site 30
Y487
G
F
R
S
G
R
H
Y
W
E
V
E
V
G
G
Site 31
S506
A
V
G
A
A
R
E
S
T
H
H
K
E
K
V
Site 32
T507
V
G
A
A
R
E
S
T
H
H
K
E
K
V
G
Site 33
S518
E
K
V
G
P
G
G
S
S
V
G
S
G
D
A
Site 34
S519
K
V
G
P
G
G
S
S
V
G
S
G
D
A
S
Site 35
S522
P
G
G
S
S
V
G
S
G
D
A
S
S
S
R
Site 36
S526
S
V
G
S
G
D
A
S
S
S
R
H
H
H
R
Site 37
S527
V
G
S
G
D
A
S
S
S
R
H
H
H
R
R
Site 38
S528
G
S
G
D
A
S
S
S
R
H
H
H
R
R
R
Site 39
Y559
V
G
T
N
G
K
R
Y
Q
A
Q
S
S
T
E
Site 40
S563
G
K
R
Y
Q
A
Q
S
S
T
E
Q
T
L
L
Site 41
T568
A
Q
S
S
T
E
Q
T
L
L
S
P
S
E
K
Site 42
S571
S
T
E
Q
T
L
L
S
P
S
E
K
P
R
R
Site 43
S573
E
Q
T
L
L
S
P
S
E
K
P
R
R
F
G
Site 44
Y582
K
P
R
R
F
G
V
Y
L
D
Y
E
A
G
R
Site 45
Y585
R
F
G
V
Y
L
D
Y
E
A
G
R
L
G
F
Site 46
Y593
E
A
G
R
L
G
F
Y
N
A
E
T
L
A
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation