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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MGC32065
Full Name:
Sorting nexin-33
Alias:
SH3PX3; SH3PXD3C; SHPX3; SNX30; Sorting nexin 33
Type:
Unknown function
Mass (Da):
65265
Number AA:
574
UniProt ID:
Q8WV41
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0035091
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007154
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y9
A
L
K
G
R
A
L
Y
D
F
H
S
E
N
K
Site 2
S13
R
A
L
Y
D
F
H
S
E
N
K
E
E
I
S
Site 3
S44
G
W
L
Q
G
Q
N
S
R
G
E
T
G
L
F
Site 4
T48
G
Q
N
S
R
G
E
T
G
L
F
P
A
S
Y
Site 5
S61
S
Y
V
E
I
V
R
S
G
I
S
T
N
H
A
Site 6
T65
I
V
R
S
G
I
S
T
N
H
A
D
Y
S
S
Site 7
Y70
I
S
T
N
H
A
D
Y
S
S
S
P
A
G
S
Site 8
S71
S
T
N
H
A
D
Y
S
S
S
P
A
G
S
P
Site 9
S72
T
N
H
A
D
Y
S
S
S
P
A
G
S
P
G
Site 10
S73
N
H
A
D
Y
S
S
S
P
A
G
S
P
G
A
Site 11
S77
Y
S
S
S
P
A
G
S
P
G
A
Q
V
S
L
Site 12
S83
G
S
P
G
A
Q
V
S
L
Y
N
S
P
S
V
Site 13
Y85
P
G
A
Q
V
S
L
Y
N
S
P
S
V
A
S
Site 14
S87
A
Q
V
S
L
Y
N
S
P
S
V
A
S
P
A
Site 15
S89
V
S
L
Y
N
S
P
S
V
A
S
P
A
R
S
Site 16
S92
Y
N
S
P
S
V
A
S
P
A
R
S
G
G
G
Site 17
S96
S
V
A
S
P
A
R
S
G
G
G
S
G
F
L
Site 18
S100
P
A
R
S
G
G
G
S
G
F
L
S
N
Q
G
Site 19
S104
G
G
G
S
G
F
L
S
N
Q
G
S
F
E
E
Site 20
S108
G
F
L
S
N
Q
G
S
F
E
E
D
D
D
D
Site 21
T125
D
D
W
D
D
G
C
T
V
V
E
E
P
R
A
Site 22
S146
G
H
P
P
L
N
L
S
Y
P
G
A
Y
P
S
Site 23
Y147
H
P
P
L
N
L
S
Y
P
G
A
Y
P
S
Q
Site 24
Y151
N
L
S
Y
P
G
A
Y
P
S
Q
H
M
A
F
Site 25
S153
S
Y
P
G
A
Y
P
S
Q
H
M
A
F
R
P
Site 26
S169
P
P
L
E
R
Q
D
S
L
A
S
A
K
R
G
Site 27
S172
E
R
Q
D
S
L
A
S
A
K
R
G
S
V
V
Site 28
S177
L
A
S
A
K
R
G
S
V
V
G
R
N
L
N
Site 29
S187
G
R
N
L
N
R
F
S
C
F
V
R
S
G
V
Site 30
S248
T
K
F
K
G
I
K
S
Y
I
S
Y
K
L
T
Site 31
Y249
K
F
K
G
I
K
S
Y
I
S
Y
K
L
T
P
Site 32
Y252
G
I
K
S
Y
I
S
Y
K
L
T
P
T
H
A
Site 33
T255
S
Y
I
S
Y
K
L
T
P
T
H
A
A
S
P
Site 34
T257
I
S
Y
K
L
T
P
T
H
A
A
S
P
V
Y
Site 35
S261
L
T
P
T
H
A
A
S
P
V
Y
R
R
Y
K
Site 36
Y264
T
H
A
A
S
P
V
Y
R
R
Y
K
H
F
D
Site 37
Y267
A
S
P
V
Y
R
R
Y
K
H
F
D
W
L
Y
Site 38
Y274
Y
K
H
F
D
W
L
Y
N
R
L
L
H
K
F
Site 39
T282
N
R
L
L
H
K
F
T
V
I
S
V
P
H
L
Site 40
S285
L
H
K
F
T
V
I
S
V
P
H
L
P
E
K
Site 41
T295
H
L
P
E
K
Q
A
T
G
R
F
E
E
D
F
Site 42
S324
M
T
S
H
P
V
L
S
Q
Y
E
G
F
Q
H
Site 43
Y326
S
H
P
V
L
S
Q
Y
E
G
F
Q
H
F
L
Site 44
T380
D
V
E
D
R
V
D
T
F
K
A
F
S
K
K
Site 45
S391
F
S
K
K
M
D
D
S
V
L
Q
L
S
T
V
Site 46
S425
G
S
A
F
Q
A
I
S
H
S
F
Q
M
D
P
Site 47
S427
A
F
Q
A
I
S
H
S
F
Q
M
D
P
P
F
Site 48
S436
Q
M
D
P
P
F
C
S
E
A
L
N
S
A
I
Site 49
S441
F
C
S
E
A
L
N
S
A
I
S
H
T
G
R
Site 50
S444
E
A
L
N
S
A
I
S
H
T
G
R
T
Y
E
Site 51
Y450
I
S
H
T
G
R
T
Y
E
A
I
G
E
M
F
Site 52
S499
A
F
A
K
V
K
E
S
Q
R
M
S
D
E
G
Site 53
S503
V
K
E
S
Q
R
M
S
D
E
G
R
M
V
Q
Site 54
Y557
L
R
Q
Q
I
L
F
Y
Q
R
V
G
Q
Q
L
Site 55
T567
V
G
Q
Q
L
E
K
T
L
R
M
Y
D
N
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation