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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Depdc1b
Full Name:
DEP domain-containing protein 1B
Alias:
Brcc3; Breast cancer cell 3; Dep domain containing 1b; Flj11252; HBV X-transactivated gene 8 protein; Xtp1
Type:
Mass (Da):
61771
Number AA:
529
UniProt ID:
Q8WUY9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005096
PhosphoSite+
KinaseNET
Biological Process:
GO:0007242
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
G
P
G
P
Y
R
A
T
R
L
W
N
E
T
V
Site 2
T20
A
T
R
L
W
N
E
T
V
E
L
F
R
A
K
Site 3
S39
K
H
R
C
R
F
K
S
Y
E
H
C
F
T
A
Site 4
S60
L
H
E
L
L
R
C
S
Q
N
F
G
P
E
V
Site 5
T72
P
E
V
T
R
K
Q
T
V
Q
L
L
K
K
F
Site 6
Y104
F
E
D
N
R
H
L
Y
R
F
P
P
S
S
P
Site 7
S109
H
L
Y
R
F
P
P
S
S
P
L
K
P
Y
P
Site 8
S110
L
Y
R
F
P
P
S
S
P
L
K
P
Y
P
K
Site 9
Y115
P
S
S
P
L
K
P
Y
P
K
K
P
P
N
Q
Site 10
S139
N
D
L
P
P
G
T
S
Q
E
N
I
P
V
R
Site 11
S160
E
M
W
Y
K
R
H
S
I
A
I
G
E
V
P
Site 12
T178
L
V
H
R
R
Q
L
T
E
A
N
V
E
E
I
Site 13
T190
E
E
I
W
K
S
M
T
L
S
Y
L
Q
K
I
Site 14
S236
V
V
I
L
D
D
K
S
K
E
L
P
H
W
V
Site 15
Y264
S
D
L
K
Q
P
M
Y
L
G
F
E
K
D
V
Site 16
Y278
V
F
K
T
I
A
D
Y
Y
G
H
L
K
E
P
Site 17
Y279
F
K
T
I
A
D
Y
Y
G
H
L
K
E
P
L
Site 18
S367
F
S
R
C
I
L
C
S
K
D
E
V
D
L
D
Site 19
Y417
L
R
R
V
Q
I
K
Y
P
G
A
D
M
D
I
Site 20
S427
A
D
M
D
I
T
L
S
A
P
S
F
C
R
Q
Site 21
S430
D
I
T
L
S
A
P
S
F
C
R
Q
I
S
P
Site 22
S436
P
S
F
C
R
Q
I
S
P
E
E
F
E
Y
Q
Site 23
Y442
I
S
P
E
E
F
E
Y
Q
R
S
Y
G
S
Q
Site 24
S445
E
E
F
E
Y
Q
R
S
Y
G
S
Q
E
P
L
Site 25
Y446
E
F
E
Y
Q
R
S
Y
G
S
Q
E
P
L
A
Site 26
S448
E
Y
Q
R
S
Y
G
S
Q
E
P
L
A
A
L
Site 27
T461
A
L
L
E
E
V
I
T
D
A
K
L
S
N
K
Site 28
S480
K
L
K
Q
F
Q
K
S
Y
P
E
V
Y
Q
E
Site 29
Y481
L
K
Q
F
Q
K
S
Y
P
E
V
Y
Q
E
R
Site 30
Y485
Q
K
S
Y
P
E
V
Y
Q
E
R
F
P
T
P
Site 31
T491
V
Y
Q
E
R
F
P
T
P
E
S
A
A
L
L
Site 32
S494
E
R
F
P
T
P
E
S
A
A
L
L
F
P
E
Site 33
S526
Q
P
F
Q
R
T
R
S
F
R
M
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation