KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
SETD7
Full Name:
Histone-lysine N-methyltransferase SETD7
Alias:
Histone H3-K4 methyltransferase SETD7;Lysine N-methyltransferase 7;SET domain-containing protein 7;SET7/9
Type:
Mass (Da):
40721
Number AA:
366
UniProt ID:
Q8WTS6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T27
G
L
P
H
G
F
C
T
V
T
Y
S
S
T
D
Site 2
T29
P
H
G
F
C
T
V
T
Y
S
S
T
D
R
F
Site 3
S31
G
F
C
T
V
T
Y
S
S
T
D
R
F
E
G
Site 4
S32
F
C
T
V
T
Y
S
S
T
D
R
F
E
G
N
Site 5
T33
C
T
V
T
Y
S
S
T
D
R
F
E
G
N
F
Site 6
Y62
D
G
S
T
L
E
G
Y
Y
V
D
D
A
L
Q
Site 7
Y63
G
S
T
L
E
G
Y
Y
V
D
D
A
L
Q
G
Site 8
T75
L
Q
G
Q
G
V
Y
T
Y
E
D
G
G
V
L
Site 9
Y76
Q
G
Q
G
V
Y
T
Y
E
D
G
G
V
L
Q
Site 10
T85
D
G
G
V
L
Q
G
T
Y
V
D
G
E
L
N
Site 11
Y86
G
G
V
L
Q
G
T
Y
V
D
G
E
L
N
G
Site 12
Y98
L
N
G
P
A
Q
E
Y
D
T
D
G
R
L
I
Site 13
T100
G
P
A
Q
E
Y
D
T
D
G
R
L
I
F
K
Site 14
Y110
R
L
I
F
K
G
Q
Y
K
D
N
I
R
H
G
Site 15
Y122
R
H
G
V
C
W
I
Y
Y
P
D
G
G
S
L
Site 16
Y146
M
T
G
E
K
I
A
Y
V
Y
P
D
E
R
T
Site 17
Y148
G
E
K
I
A
Y
V
Y
P
D
E
R
T
A
L
Site 18
Y156
P
D
E
R
T
A
L
Y
G
K
F
I
D
G
E
Site 19
S174
G
K
L
A
T
L
M
S
T
E
E
G
R
P
H
Site 20
T175
K
L
A
T
L
M
S
T
E
E
G
R
P
H
F
Site 21
S189
F
E
L
M
P
G
N
S
V
Y
H
F
D
K
S
Site 22
Y191
L
M
P
G
N
S
V
Y
H
F
D
K
S
T
S
Site 23
S196
S
V
Y
H
F
D
K
S
T
S
S
C
I
S
T
Site 24
T197
V
Y
H
F
D
K
S
T
S
S
C
I
S
T
N
Site 25
S198
Y
H
F
D
K
S
T
S
S
C
I
S
T
N
A
Site 26
S199
H
F
D
K
S
T
S
S
C
I
S
T
N
A
L
Site 27
S202
K
S
T
S
S
C
I
S
T
N
A
L
L
P
D
Site 28
T203
S
T
S
S
C
I
S
T
N
A
L
L
P
D
P
Site 29
Y211
N
A
L
L
P
D
P
Y
E
S
E
R
V
Y
V
Site 30
Y217
P
Y
E
S
E
R
V
Y
V
A
E
S
L
I
S
Site 31
S221
E
R
V
Y
V
A
E
S
L
I
S
S
A
G
E
Site 32
Y245
P
N
T
V
M
S
F
Y
N
G
V
R
I
T
H
Site 33
T251
F
Y
N
G
V
R
I
T
H
Q
E
V
D
S
R
Site 34
T273
T
L
S
L
D
E
E
T
V
I
D
V
P
E
P
Site 35
Y281
V
I
D
V
P
E
P
Y
N
H
V
S
K
Y
C
Site 36
Y287
P
Y
N
H
V
S
K
Y
C
A
S
L
G
H
K
Site 37
Y305
S
F
T
P
N
C
I
Y
D
M
F
V
H
P
R
Site 38
T321
G
P
I
K
C
I
R
T
L
R
A
V
E
A
D
Site 39
T332
V
E
A
D
E
E
L
T
V
A
Y
G
Y
D
H
Site 40
Y337
E
L
T
V
A
Y
G
Y
D
H
S
P
P
G
K
Site 41
S340
V
A
Y
G
Y
D
H
S
P
P
G
K
S
G
P
Site 42
S345
D
H
S
P
P
G
K
S
G
P
E
A
P
E
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation