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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF418
Full Name:
Zinc finger protein 418
Alias:
Type:
Mass (Da):
77858
Number AA:
676
UniProt ID:
Q8TF45
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
E
D
V
A
V
N
F
S
Q
E
E
W
S
L
L
Site 2
S20
N
F
S
Q
E
E
W
S
L
L
S
E
V
Q
R
Site 3
S23
Q
E
E
W
S
L
L
S
E
V
Q
R
C
L
Y
Site 4
Y30
S
E
V
Q
R
C
L
Y
H
D
V
M
L
E
N
Site 5
S50
S
L
G
C
W
C
G
S
E
D
E
E
A
P
S
Site 6
S57
S
E
D
E
E
A
P
S
K
K
S
I
S
I
Q
Site 7
S62
A
P
S
K
K
S
I
S
I
Q
R
V
S
Q
V
Site 8
S67
S
I
S
I
Q
R
V
S
Q
V
S
T
P
G
A
Site 9
S70
I
Q
R
V
S
Q
V
S
T
P
G
A
G
V
S
Site 10
T71
Q
R
V
S
Q
V
S
T
P
G
A
G
V
S
P
Site 11
S77
S
T
P
G
A
G
V
S
P
K
K
A
H
S
C
Site 12
Y120
E
A
W
G
N
K
L
Y
D
S
S
N
R
P
H
Site 13
S123
G
N
K
L
Y
D
S
S
N
R
P
H
Q
N
Q
Site 14
Y131
N
R
P
H
Q
N
Q
Y
L
G
E
K
P
Y
R
Site 15
S140
G
E
K
P
Y
R
S
S
V
E
E
A
L
F
V
Site 16
S155
K
R
C
K
F
H
V
S
E
E
S
S
I
F
I
Site 17
S159
F
H
V
S
E
E
S
S
I
F
I
Q
S
G
K
Site 18
S164
E
S
S
I
F
I
Q
S
G
K
D
F
L
P
S
Site 19
S171
S
G
K
D
F
L
P
S
S
G
L
L
L
Q
E
Site 20
S172
G
K
D
F
L
P
S
S
G
L
L
L
Q
E
A
Site 21
T182
L
L
Q
E
A
T
H
T
G
E
K
S
N
S
K
Site 22
S188
H
T
G
E
K
S
N
S
K
P
E
C
E
S
P
Site 23
S194
N
S
K
P
E
C
E
S
P
F
Q
W
G
D
T
Site 24
Y231
L
P
S
R
E
E
C
Y
C
W
E
C
G
K
S
Site 25
S240
W
E
C
G
K
S
F
S
K
Y
D
S
V
S
N
Site 26
Y242
C
G
K
S
F
S
K
Y
D
S
V
S
N
H
Q
Site 27
S244
K
S
F
S
K
Y
D
S
V
S
N
H
Q
R
V
Site 28
S246
F
S
K
Y
D
S
V
S
N
H
Q
R
V
H
T
Site 29
T253
S
N
H
Q
R
V
H
T
G
K
R
P
Y
E
C
Site 30
Y258
V
H
T
G
K
R
P
Y
E
C
G
E
C
G
K
Site 31
S266
E
C
G
E
C
G
K
S
F
S
H
K
G
S
L
Site 32
S268
G
E
C
G
K
S
F
S
H
K
G
S
L
V
Q
Site 33
S272
K
S
F
S
H
K
G
S
L
V
Q
H
Q
R
V
Site 34
T281
V
Q
H
Q
R
V
H
T
G
K
R
P
Y
E
C
Site 35
T309
V
Q
H
Q
R
V
H
T
G
E
R
P
Y
E
C
Site 36
Y314
V
H
T
G
E
R
P
Y
E
C
G
E
C
G
K
Site 37
S322
E
C
G
E
C
G
K
S
F
S
Q
N
G
T
L
Site 38
S324
G
E
C
G
K
S
F
S
Q
N
G
T
L
I
K
Site 39
T328
K
S
F
S
Q
N
G
T
L
I
K
H
Q
R
V
Site 40
T337
I
K
H
Q
R
V
H
T
G
E
R
P
Y
E
C
Site 41
Y342
V
H
T
G
E
R
P
Y
E
C
E
E
C
G
K
Site 42
T365
I
Q
H
Q
R
G
H
T
S
E
R
P
Y
E
C
Site 43
S366
Q
H
Q
R
G
H
T
S
E
R
P
Y
E
C
E
Site 44
Y370
G
H
T
S
E
R
P
Y
E
C
E
E
C
G
K
Site 45
S380
E
E
C
G
K
C
F
S
Q
K
G
T
L
T
E
Site 46
T384
K
C
F
S
Q
K
G
T
L
T
E
H
H
R
V
Site 47
T386
F
S
Q
K
G
T
L
T
E
H
H
R
V
H
T
Site 48
T393
T
E
H
H
R
V
H
T
R
E
R
P
Y
E
C
Site 49
Y398
V
H
T
R
E
R
P
Y
E
C
G
E
C
G
K
Site 50
S406
E
C
G
E
C
G
K
S
F
S
R
K
G
H
L
Site 51
S408
G
E
C
G
K
S
F
S
R
K
G
H
L
R
N
Site 52
T421
R
N
H
Q
R
G
H
T
G
E
R
P
Y
E
C
Site 53
Y426
G
H
T
G
E
R
P
Y
E
C
G
E
C
G
K
Site 54
S434
E
C
G
E
C
G
K
S
F
S
R
K
G
N
L
Site 55
S436
G
E
C
G
K
S
F
S
R
K
G
N
L
I
Q
Site 56
T449
I
Q
H
Q
R
S
H
T
G
E
R
P
Y
E
C
Site 57
Y454
S
H
T
G
E
R
P
Y
E
C
R
E
C
R
K
Site 58
S467
R
K
L
F
R
G
K
S
H
L
I
E
H
Q
R
Site 59
T477
I
E
H
Q
R
V
H
T
G
E
R
P
Y
E
C
Site 60
Y482
V
H
T
G
E
R
P
Y
E
C
N
E
C
G
K
Site 61
S490
E
C
N
E
C
G
K
S
F
Q
D
S
S
G
F
Site 62
S494
C
G
K
S
F
Q
D
S
S
G
F
R
V
H
Q
Site 63
S495
G
K
S
F
Q
D
S
S
G
F
R
V
H
Q
R
Site 64
T505
R
V
H
Q
R
V
H
T
G
E
K
P
F
E
C
Site 65
S513
G
E
K
P
F
E
C
S
E
C
G
K
S
F
P
Site 66
S518
E
C
S
E
C
G
K
S
F
P
Q
S
C
S
L
Site 67
S522
C
G
K
S
F
P
Q
S
C
S
L
L
R
H
R
Site 68
S524
K
S
F
P
Q
S
C
S
L
L
R
H
R
R
V
Site 69
T533
L
R
H
R
R
V
H
T
G
E
R
P
Y
E
C
Site 70
S546
E
C
G
E
C
G
K
S
F
H
Q
S
S
S
L
Site 71
S550
C
G
K
S
F
H
Q
S
S
S
L
L
R
H
Q
Site 72
S552
K
S
F
H
Q
S
S
S
L
L
R
H
Q
K
T
Site 73
T559
S
L
L
R
H
Q
K
T
H
T
A
E
R
P
Y
Site 74
Y566
T
H
T
A
E
R
P
Y
E
C
R
E
C
G
K
Site 75
S576
R
E
C
G
K
F
F
S
S
L
L
E
H
R
R
Site 76
S577
E
C
G
K
F
F
S
S
L
L
E
H
R
R
V
Site 77
T586
L
E
H
R
R
V
H
T
G
E
R
P
Y
E
C
Site 78
Y591
V
H
T
G
E
R
P
Y
E
C
R
E
C
G
K
Site 79
T599
E
C
R
E
C
G
K
T
F
T
R
R
S
A
H
Site 80
T601
R
E
C
G
K
T
F
T
R
R
S
A
H
F
K
Site 81
S604
G
K
T
F
T
R
R
S
A
H
F
K
H
Q
R
Site 82
T614
F
K
H
Q
R
L
H
T
R
G
K
P
Y
E
C
Site 83
Y619
L
H
T
R
G
K
P
Y
E
C
S
E
C
G
K
Site 84
S622
R
G
K
P
Y
E
C
S
E
C
G
K
S
F
A
Site 85
S627
E
C
S
E
C
G
K
S
F
A
E
T
F
S
L
Site 86
T631
C
G
K
S
F
A
E
T
F
S
L
T
E
H
R
Site 87
S633
K
S
F
A
E
T
F
S
L
T
E
H
R
R
V
Site 88
T635
F
A
E
T
F
S
L
T
E
H
R
R
V
H
T
Site 89
T642
T
E
H
R
R
V
H
T
G
E
R
P
Y
E
C
Site 90
Y647
V
H
T
G
E
R
P
Y
E
C
S
E
C
G
K
Site 91
S650
G
E
R
P
Y
E
C
S
E
C
G
K
S
F
H
Site 92
S655
E
C
S
E
C
G
K
S
F
H
R
S
S
S
L
Site 93
S659
C
G
K
S
F
H
R
S
S
S
L
L
R
H
Q
Site 94
S660
G
K
S
F
H
R
S
S
S
L
L
R
H
Q
R
Site 95
S661
K
S
F
H
R
S
S
S
L
L
R
H
Q
R
V
Site 96
T670
L
R
H
Q
R
V
H
T
E
R
S
P
Y
K
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation