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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA1957
Full Name:
C2 calcium-dependent domain-containing protein 4C
Alias:
C2 domain-containing protein KIAA1957; F148C
Type:
Uncharacterized protein
Mass (Da):
44576
Number AA:
421
UniProt ID:
Q8TF44
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
F
L
E
R
L
R
G
S
G
E
N
G
A
A
R
Site 2
S33
S
E
A
G
D
K
A
S
K
G
P
L
Y
S
N
Site 3
Y38
K
A
S
K
G
P
L
Y
S
N
V
L
T
P
D
Site 4
S39
A
S
K
G
P
L
Y
S
N
V
L
T
P
D
K
Site 5
T43
P
L
Y
S
N
V
L
T
P
D
K
I
P
D
F
Site 6
S58
F
I
P
P
K
L
P
S
G
P
A
E
G
E
G
Site 7
S74
A
A
L
G
P
S
T
S
E
Q
N
L
A
S
A
Site 8
S80
T
S
E
Q
N
L
A
S
A
A
P
R
Q
T
P
Site 9
T86
A
S
A
A
P
R
Q
T
P
R
S
P
R
L
P
Site 10
S89
A
P
R
Q
T
P
R
S
P
R
L
P
A
K
L
Site 11
S102
K
L
A
A
E
S
K
S
L
L
K
A
A
T
R
Site 12
S122
E
S
A
E
D
W
L
S
E
E
A
T
D
A
D
Site 13
T126
D
W
L
S
E
E
A
T
D
A
D
P
Q
A
Q
Site 14
S137
P
Q
A
Q
G
A
M
S
L
P
S
V
P
K
A
Site 15
S140
Q
G
A
M
S
L
P
S
V
P
K
A
Q
T
S
Site 16
S156
G
F
A
M
L
A
E
S
P
H
T
R
R
K
E
Site 17
T159
M
L
A
E
S
P
H
T
R
R
K
E
S
L
F
Site 18
S164
P
H
T
R
R
K
E
S
L
F
H
S
E
H
G
Site 19
S168
R
K
E
S
L
F
H
S
E
H
G
A
L
A
Q
Site 20
S178
G
A
L
A
Q
V
G
S
P
G
A
G
R
R
R
Site 21
S206
E
A
G
G
A
L
M
S
P
G
R
Y
F
S
G
Site 22
Y210
A
L
M
S
P
G
R
Y
F
S
G
G
E
S
D
Site 23
S212
M
S
P
G
R
Y
F
S
G
G
E
S
D
T
G
Site 24
S216
R
Y
F
S
G
G
E
S
D
T
G
S
S
A
E
Site 25
T218
F
S
G
G
E
S
D
T
G
S
S
A
E
S
S
Site 26
S220
G
G
E
S
D
T
G
S
S
A
E
S
S
P
F
Site 27
S221
G
E
S
D
T
G
S
S
A
E
S
S
P
F
G
Site 28
S224
D
T
G
S
S
A
E
S
S
P
F
G
S
P
L
Site 29
S225
T
G
S
S
A
E
S
S
P
F
G
S
P
L
L
Site 30
S229
A
E
S
S
P
F
G
S
P
L
L
S
R
S
V
Site 31
S246
L
K
G
F
A
Q
D
S
Q
A
K
V
S
Q
L
Site 32
S251
Q
D
S
Q
A
K
V
S
Q
L
R
H
S
V
G
Site 33
S256
K
V
S
Q
L
R
H
S
V
G
R
H
G
S
L
Site 34
S262
H
S
V
G
R
H
G
S
L
S
A
D
D
S
T
Site 35
S264
V
G
R
H
G
S
L
S
A
D
D
S
T
P
D
Site 36
S268
G
S
L
S
A
D
D
S
T
P
D
A
S
P
G
Site 37
T269
S
L
S
A
D
D
S
T
P
D
A
S
P
G
S
Site 38
S273
D
D
S
T
P
D
A
S
P
G
S
R
R
R
L
Site 39
S276
T
P
D
A
S
P
G
S
R
R
R
L
T
R
R
Site 40
T281
P
G
S
R
R
R
L
T
R
R
A
P
P
E
P
Site 41
S292
P
P
E
P
G
P
E
S
G
Q
A
R
G
E
H
Site 42
T300
G
Q
A
R
G
E
H
T
V
H
V
G
P
R
G
Site 43
Y315
S
V
R
L
L
A
E
Y
E
A
G
Q
A
R
L
Site 44
S360
G
K
L
Q
K
Q
R
S
T
I
V
K
N
S
R
Site 45
T361
K
L
Q
K
Q
R
S
T
I
V
K
N
S
R
R
Site 46
S366
R
S
T
I
V
K
N
S
R
R
P
V
F
N
E
Site 47
S400
K
V
V
N
K
G
S
S
L
K
R
D
T
L
L
Site 48
T405
G
S
S
L
K
R
D
T
L
L
G
E
K
E
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation