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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANKRD24
Full Name:
Ankyrin repeat domain-containing protein 24
Alias:
ankyrin repeat domain 24; KIAA1981
Type:
Mass (Da):
124190
Number AA:
UniProt ID:
Q8TF21
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
L
R
A
R
F
K
K
T
E
L
R
L
S
P
T
Site 2
S16
K
K
T
E
L
R
L
S
P
T
D
L
G
S
C
Site 3
T18
T
E
L
R
L
S
P
T
D
L
G
S
C
P
P
Site 4
S22
L
S
P
T
D
L
G
S
C
P
P
C
G
P
C
Site 5
S42
A
A
R
G
R
R
Q
S
Q
D
W
G
K
S
D
Site 6
S48
Q
S
Q
D
W
G
K
S
D
E
R
L
L
Q
A
Site 7
S110
A
H
G
S
N
V
M
S
A
D
G
A
G
Y
N
Site 8
Y125
A
L
H
L
A
A
K
Y
G
H
P
Q
C
L
K
Site 9
T183
P
Q
D
R
S
G
A
T
P
L
I
I
A
A
Q
Site 10
T229
C
E
G
A
S
P
E
T
V
E
V
L
L
Q
G
Site 11
T243
G
G
A
Q
P
G
I
T
D
A
L
G
Q
D
A
Site 12
Y253
L
G
Q
D
A
A
H
Y
G
A
L
A
G
D
K
Site 13
S274
Q
E
A
A
Q
R
P
S
P
P
S
A
L
T
E
Site 14
S277
A
Q
R
P
S
P
P
S
A
L
T
E
D
D
S
Site 15
T280
P
S
P
P
S
A
L
T
E
D
D
S
G
E
A
Site 16
S284
S
A
L
T
E
D
D
S
G
E
A
S
S
Q
N
Site 17
S288
E
D
D
S
G
E
A
S
S
Q
N
S
M
S
S
Site 18
S289
D
D
S
G
E
A
S
S
Q
N
S
M
S
S
H
Site 19
S292
G
E
A
S
S
Q
N
S
M
S
S
H
G
K
Q
Site 20
S294
A
S
S
Q
N
S
M
S
S
H
G
K
Q
G
A
Site 21
S295
S
S
Q
N
S
M
S
S
H
G
K
Q
G
A
P
Site 22
S313
K
A
P
P
P
P
A
S
I
P
M
P
D
D
R
Site 23
Y323
M
P
D
D
R
D
A
Y
E
E
I
V
R
L
R
Site 24
S354
K
E
R
R
Q
Q
E
S
P
E
A
S
S
L
H
Site 25
S358
Q
Q
E
S
P
E
A
S
S
L
H
I
L
E
R
Site 26
S383
E
R
Q
E
E
K
E
S
L
G
R
E
V
E
S
Site 27
S390
S
L
G
R
E
V
E
S
L
Q
S
R
L
S
L
Site 28
S393
R
E
V
E
S
L
Q
S
R
L
S
L
L
E
N
Site 29
S396
E
S
L
Q
S
R
L
S
L
L
E
N
E
R
E
Site 30
T405
L
E
N
E
R
E
N
T
S
Y
D
V
T
T
L
Site 31
Y407
N
E
R
E
N
T
S
Y
D
V
T
T
L
Q
D
Site 32
T410
E
N
T
S
Y
D
V
T
T
L
Q
D
E
E
G
Site 33
T411
N
T
S
Y
D
V
T
T
L
Q
D
E
E
G
E
Site 34
S430
P
G
A
E
V
L
L
S
R
Q
L
S
P
S
A
Site 35
S434
V
L
L
S
R
Q
L
S
P
S
A
Q
E
H
L
Site 36
S436
L
S
R
Q
L
S
P
S
A
Q
E
H
L
A
S
Site 37
S443
S
A
Q
E
H
L
A
S
L
Q
E
Q
V
A
V
Site 38
T473
E
N
F
E
K
D
E
T
Q
M
E
V
E
A
L
Site 39
S491
I
P
L
A
L
Y
D
S
L
R
A
E
F
D
Q
Site 40
S549
T
H
M
E
L
N
G
S
V
A
P
E
T
K
V
Site 41
T554
N
G
S
V
A
P
E
T
K
V
N
G
A
E
T
Site 42
T571
E
E
A
A
G
D
E
T
M
E
A
R
T
M
E
Site 43
T576
D
E
T
M
E
A
R
T
M
E
A
E
A
T
G
Site 44
T582
R
T
M
E
A
E
A
T
G
A
E
A
T
G
A
Site 45
T597
E
A
T
G
A
K
V
T
E
T
K
P
T
G
A
Site 46
T599
T
G
A
K
V
T
E
T
K
P
T
G
A
E
V
Site 47
T612
E
V
R
E
M
E
T
T
E
E
E
A
N
M
E
Site 48
T620
E
E
E
A
N
M
E
T
K
P
T
G
A
Q
A
Site 49
T630
T
G
A
Q
A
T
D
T
E
T
T
G
V
E
A
Site 50
T645
M
G
V
E
A
T
K
T
K
A
E
E
A
E
M
Site 51
Y655
E
E
A
E
M
Q
A
Y
G
V
G
A
G
Q
A
Site 52
T667
G
Q
A
E
P
P
V
T
G
T
T
N
M
E
A
Site 53
S677
T
N
M
E
A
T
G
S
R
A
T
G
M
E
S
Site 54
T680
E
A
T
G
S
R
A
T
G
M
E
S
T
G
V
Site 55
S684
S
R
A
T
G
M
E
S
T
G
V
S
A
T
G
Site 56
S688
G
M
E
S
T
G
V
S
A
T
G
V
E
N
P
Site 57
T700
E
N
P
G
V
E
A
T
V
P
G
I
S
A
G
Site 58
S774
R
V
R
E
A
E
G
S
G
A
S
G
G
G
G
Site 59
T784
S
G
G
G
G
G
D
T
T
Q
L
R
A
A
L
Site 60
T785
G
G
G
G
G
D
T
T
Q
L
R
A
A
L
E
Site 61
S803
E
D
L
R
D
R
D
S
R
L
R
E
L
E
A
Site 62
S821
C
L
D
E
A
R
A
S
R
L
L
A
E
E
E
Site 63
T859
V
L
R
E
Q
L
A
T
A
R
A
T
G
E
Q
Site 64
T863
Q
L
A
T
A
R
A
T
G
E
Q
Q
R
T
A
Site 65
T869
A
T
G
E
Q
Q
R
T
A
A
A
E
L
G
R
Site 66
S906
L
A
E
L
R
E
A
S
E
A
L
R
Q
S
V
Site 67
S912
A
S
E
A
L
R
Q
S
V
V
P
A
S
E
H
Site 68
S917
R
Q
S
V
V
P
A
S
E
H
R
R
L
Q
E
Site 69
S935
E
L
R
G
R
A
A
S
L
E
Q
E
V
V
A
Site 70
S961
L
E
R
E
R
V
C
S
V
A
L
S
E
H
E
Site 71
T995
L
G
R
R
H
E
K
T
S
A
E
V
F
Q
V
Site 72
S996
G
R
R
H
E
K
T
S
A
E
V
F
Q
V
Q
Site 73
S1011
R
E
A
L
F
M
K
S
E
R
H
A
A
E
A
Site 74
T1081
E
Q
P
A
A
L
A
T
P
E
V
E
A
L
R
Site 75
S1106
Q
E
A
A
R
D
H
S
S
V
V
A
L
Y
R
Site 76
S1107
E
A
A
R
D
H
S
S
V
V
A
L
Y
R
S
Site 77
Y1118
L
Y
R
S
H
L
L
Y
A
I
Q
G
Q
M
D
Site 78
S1133
E
D
V
Q
R
I
L
S
Q
I
L
Q
M
Q
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation