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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ADAMTS17
Full Name:
A disintegrin and metalloproteinase with thrombospondin motifs 17
Alias:
Type:
Mass (Da):
121127
Number AA:
1095
UniProt ID:
Q8TE56
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T67
R
R
R
R
R
P
R
T
P
P
A
A
P
R
A
Site 2
Y93
P
A
F
G
R
D
L
Y
L
Q
L
R
R
D
L
Site 3
S104
R
R
D
L
R
F
L
S
R
G
F
E
V
E
E
Site 4
Y127
R
P
A
E
L
C
F
Y
S
G
R
V
L
G
H
Site 5
S169
L
I
Q
P
L
N
N
S
Q
G
P
F
S
G
R
Site 6
S174
N
N
S
Q
G
P
F
S
G
R
E
H
L
I
R
Site 7
S185
H
L
I
R
R
K
W
S
L
T
P
S
P
S
A
Site 8
T187
I
R
R
K
W
S
L
T
P
S
P
S
A
E
A
Site 9
S189
R
K
W
S
L
T
P
S
P
S
A
E
A
Q
R
Site 10
S191
W
S
L
T
P
S
P
S
A
E
A
Q
R
P
E
Site 11
T205
E
Q
L
C
K
V
L
T
E
K
K
K
P
T
W
Site 12
S216
K
P
T
W
G
R
P
S
R
D
W
R
E
R
R
Site 13
T229
R
R
N
A
I
R
L
T
S
E
H
T
V
E
T
Site 14
S230
R
N
A
I
R
L
T
S
E
H
T
V
E
T
L
Site 15
S295
R
Q
R
P
A
K
L
S
I
G
H
H
G
E
R
Site 16
T357
H
K
D
E
P
C
D
T
V
G
I
A
Y
L
G
Site 17
S414
A
G
R
S
H
I
M
S
G
E
W
V
K
G
R
Site 18
S424
W
V
K
G
R
N
P
S
D
L
S
W
S
S
C
Site 19
S427
G
R
N
P
S
D
L
S
W
S
S
C
S
R
D
Site 20
S430
P
S
D
L
S
W
S
S
C
S
R
D
D
L
E
Site 21
T451
V
S
T
C
L
L
V
T
D
P
R
S
Q
H
T
Site 22
S455
L
L
V
T
D
P
R
S
Q
H
T
V
R
L
P
Site 23
T458
T
D
P
R
S
Q
H
T
V
R
L
P
H
K
L
Site 24
Y470
H
K
L
P
G
M
H
Y
S
A
N
E
Q
C
Q
Site 25
T506
W
C
L
V
E
G
D
T
S
C
K
T
K
L
D
Site 26
S507
C
L
V
E
G
D
T
S
C
K
T
K
L
D
P
Site 27
T510
E
G
D
T
S
C
K
T
K
L
D
P
P
L
D
Site 28
T519
L
D
P
P
L
D
G
T
E
C
G
A
D
K
W
Site 29
S534
C
R
A
G
E
C
V
S
K
T
P
I
P
E
H
Site 30
T536
A
G
E
C
V
S
K
T
P
I
P
E
H
V
D
Site 31
T580
P
P
P
G
P
G
G
T
H
C
P
G
A
S
V
Site 32
S603
P
C
P
K
G
L
P
S
F
R
D
Q
Q
C
Q
Site 33
S616
C
Q
A
H
D
R
L
S
P
K
K
K
G
L
L
Site 34
T624
P
K
K
K
G
L
L
T
A
V
V
V
D
D
K
Site 35
Y636
D
D
K
P
C
E
L
Y
C
S
P
L
G
K
E
Site 36
S638
K
P
C
E
L
Y
C
S
P
L
G
K
E
S
P
Site 37
S644
C
S
P
L
G
K
E
S
P
L
L
V
A
D
R
Site 38
T656
A
D
R
V
L
D
G
T
P
C
G
P
Y
E
T
Site 39
Y661
D
G
T
P
C
G
P
Y
E
T
D
L
C
V
H
Site 40
S682
G
C
D
G
I
I
G
S
A
A
K
E
D
R
C
Site 41
T698
V
C
S
G
D
G
K
T
C
H
L
V
K
G
D
Site 42
S707
H
L
V
K
G
D
F
S
H
A
R
G
T
A
L
Site 43
T712
D
F
S
H
A
R
G
T
A
L
K
D
S
G
K
Site 44
S717
R
G
T
A
L
K
D
S
G
K
G
S
I
N
S
Site 45
S721
L
K
D
S
G
K
G
S
I
N
S
D
W
K
I
Site 46
S724
S
G
K
G
S
I
N
S
D
W
K
I
E
L
P
Site 47
Y743
I
A
G
T
T
V
R
Y
V
R
R
G
L
W
E
Site 48
S753
R
G
L
W
E
K
I
S
A
K
G
P
T
K
L
Site 49
Y774
L
L
F
H
D
Q
D
Y
G
I
H
Y
E
Y
T
Site 50
Y778
D
Q
D
Y
G
I
H
Y
E
Y
T
V
P
V
N
Site 51
Y780
D
Y
G
I
H
Y
E
Y
T
V
P
V
N
R
T
Site 52
S800
E
P
E
K
P
Q
D
S
L
F
I
W
T
H
S
Site 53
T823
C
G
G
G
E
R
R
T
I
V
S
C
T
R
I
Site 54
S826
G
E
R
R
T
I
V
S
C
T
R
I
V
N
K
Site 55
T834
C
T
R
I
V
N
K
T
T
T
L
V
N
D
S
Site 56
T836
R
I
V
N
K
T
T
T
L
V
N
D
S
D
C
Site 57
S841
T
T
T
L
V
N
D
S
D
C
P
Q
A
S
R
Site 58
S847
D
S
D
C
P
Q
A
S
R
P
E
P
Q
V
R
Site 59
S874
A
G
P
W
S
P
C
S
A
T
C
E
K
G
F
Site 60
Y890
H
R
E
V
T
C
V
Y
Q
L
Q
N
G
T
H
Site 61
Y904
H
V
A
T
R
P
L
Y
C
P
G
P
R
P
A
Site 62
S915
P
R
P
A
A
V
Q
S
C
E
G
Q
D
C
L
Site 63
S934
A
S
E
W
S
Q
C
S
A
S
C
G
K
G
V
Site 64
T945
G
K
G
V
W
K
R
T
V
A
C
T
N
S
Q
Site 65
S951
R
T
V
A
C
T
N
S
Q
G
K
C
D
A
S
Site 66
S958
S
Q
G
K
C
D
A
S
T
R
P
R
A
E
E
Site 67
T959
Q
G
K
C
D
A
S
T
R
P
R
A
E
E
A
Site 68
Y970
A
E
E
A
C
E
D
Y
S
G
C
Y
E
W
K
Site 69
S985
T
G
D
W
S
T
C
S
S
T
C
G
K
G
L
Site 70
S986
G
D
W
S
T
C
S
S
T
C
G
K
G
L
Q
Site 71
S1009
K
V
T
G
R
H
G
S
E
C
P
A
L
S
K
Site 72
S1015
G
S
E
C
P
A
L
S
K
P
A
P
Y
R
Q
Site 73
Y1024
P
A
P
Y
R
Q
C
Y
Q
E
V
C
N
D
R
Site 74
T1036
N
D
R
I
N
A
N
T
I
T
S
P
R
L
A
Site 75
T1046
S
P
R
L
A
A
L
T
Y
K
C
T
R
D
Q
Site 76
Y1047
P
R
L
A
A
L
T
Y
K
C
T
R
D
Q
W
Site 77
Y1057
T
R
D
Q
W
T
V
Y
C
R
V
I
R
E
K
Site 78
Y1084
C
Q
T
C
R
D
F
Y
A
N
K
M
R
Q
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation