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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RB1CC1
Full Name:
RB1-inducible coiled-coil protein 1
Alias:
200 kDa FAK family kinase-interacting protein; Cc1; DRAGOU14; FIP200; KIAA0203; Rb1-inducible coiled coil protein; RB1-inducible coiled-coil 1; RBCC1; RBICC
Type:
Unknown function
Mass (Da):
183091
Number AA:
1594
UniProt ID:
Q8TDY2
International Prot ID:
IPI00783392
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0070969
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007049
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
RB1-inducible coiled-coil protein 1 pan-specific antibody AB-NN376-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN376-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T24
D
T
E
L
T
V
Q
T
V
A
D
L
K
H
A
Site 2
Y36
K
H
A
I
Q
S
K
Y
K
I
A
I
Q
H
Q
Site 3
T61
A
A
D
R
R
V
C
T
Y
S
A
G
T
D
T
Site 4
Y62
A
D
R
R
V
C
T
Y
S
A
G
T
D
T
N
Site 5
S63
D
R
R
V
C
T
Y
S
A
G
T
D
T
N
P
Site 6
T68
T
Y
S
A
G
T
D
T
N
P
I
F
L
F
N
Site 7
T90
R
P
P
A
I
P
K
T
T
F
S
T
E
N
D
Site 8
T91
P
P
A
I
P
K
T
T
F
S
T
E
N
D
M
Site 9
S93
A
I
P
K
T
T
F
S
T
E
N
D
M
E
I
Site 10
S105
M
E
I
K
V
E
E
S
L
M
M
P
A
V
F
Site 11
T114
M
M
P
A
V
F
H
T
V
A
S
R
T
Q
L
Site 12
S117
A
V
F
H
T
V
A
S
R
T
Q
L
A
L
E
Site 13
S134
E
V
A
K
K
L
C
S
F
C
E
G
L
V
H
Site 14
S163
N
L
E
D
C
S
N
S
Y
Q
K
L
L
F
K
Site 15
S173
K
L
L
F
K
F
E
S
I
Y
S
N
Y
L
Q
Site 16
Y175
L
F
K
F
E
S
I
Y
S
N
Y
L
Q
S
I
Site 17
S176
F
K
F
E
S
I
Y
S
N
Y
L
Q
S
I
E
Site 18
S212
L
E
C
L
T
R
H
S
Y
R
E
C
L
G
R
Site 19
Y213
E
C
L
T
R
H
S
Y
R
E
C
L
G
R
L
Site 20
S222
E
C
L
G
R
L
D
S
L
P
E
H
E
D
S
Site 21
S229
S
L
P
E
H
E
D
S
E
K
A
E
M
K
R
Site 22
S237
E
K
A
E
M
K
R
S
T
E
L
V
L
S
P
Site 23
T238
K
A
E
M
K
R
S
T
E
L
V
L
S
P
D
Site 24
S243
R
S
T
E
L
V
L
S
P
D
M
P
R
T
T
Site 25
T249
L
S
P
D
M
P
R
T
T
N
E
S
L
L
T
Site 26
T250
S
P
D
M
P
R
T
T
N
E
S
L
L
T
S
Site 27
S253
M
P
R
T
T
N
E
S
L
L
T
S
F
P
K
Site 28
T256
T
T
N
E
S
L
L
T
S
F
P
K
S
V
E
Site 29
S257
T
N
E
S
L
L
T
S
F
P
K
S
V
E
H
Site 30
S261
L
L
T
S
F
P
K
S
V
E
H
V
S
P
D
Site 31
S266
P
K
S
V
E
H
V
S
P
D
T
A
D
A
E
Site 32
T269
V
E
H
V
S
P
D
T
A
D
A
E
S
G
K
Site 33
S281
S
G
K
E
I
R
E
S
C
Q
S
T
V
H
Q
Site 34
S284
E
I
R
E
S
C
Q
S
T
V
H
Q
Q
D
E
Site 35
T285
I
R
E
S
C
Q
S
T
V
H
Q
Q
D
E
T
Site 36
S323
D
R
P
N
D
V
E
S
L
V
R
K
C
F
D
Site 37
S331
L
V
R
K
C
F
D
S
M
S
R
L
D
P
R
Site 38
S333
R
K
C
F
D
S
M
S
R
L
D
P
R
I
I
Site 39
T350
F
I
A
E
C
R
Q
T
I
A
K
L
D
N
Q
Site 40
Y370
K
G
L
E
D
R
L
Y
A
L
D
Q
M
I
A
Site 41
S490
V
K
I
V
E
A
L
S
T
V
P
Q
M
Y
C
Site 42
Y513
R
K
M
F
I
K
H
Y
R
E
W
A
G
A
L
Site 43
Y528
V
K
D
G
K
R
L
Y
E
A
E
K
S
K
R
Site 44
S533
R
L
Y
E
A
E
K
S
K
R
E
S
F
G
K
Site 45
S537
R
L
Y
E
A
E
K
S
K
R
E
S
F
G
K
Site 46
S545
F
G
K
L
F
R
K
S
F
L
R
N
R
L
F
Site 47
S557
R
L
F
R
G
L
D
S
W
P
P
S
F
C
T
Site 48
S561
G
L
D
S
W
P
P
S
F
C
T
Q
K
P
R
Site 49
T564
S
W
P
P
S
F
C
T
Q
K
P
R
K
F
D
Site 50
S578
D
C
E
L
P
D
I
S
L
K
D
L
Q
F
L
Site 51
S587
K
D
L
Q
F
L
Q
S
F
C
P
S
E
V
Q
Site 52
S624
N
L
V
K
A
A
Q
S
L
D
E
M
S
Q
T
Site 53
S629
A
Q
S
L
D
E
M
S
Q
T
I
T
D
L
L
Site 54
T631
S
L
D
E
M
S
Q
T
I
T
D
L
L
S
E
Site 55
T633
D
E
M
S
Q
T
I
T
D
L
L
S
E
Q
K
Site 56
S637
Q
T
I
T
D
L
L
S
E
Q
K
A
S
V
S
Site 57
S642
L
L
S
E
Q
K
A
S
V
S
Q
T
S
P
Q
Site 58
S644
S
E
Q
K
A
S
V
S
Q
T
S
P
Q
S
A
Site 59
T646
Q
K
A
S
V
S
Q
T
S
P
Q
S
A
S
S
Site 60
S647
K
A
S
V
S
Q
T
S
P
Q
S
A
S
S
P
Site 61
S650
V
S
Q
T
S
P
Q
S
A
S
S
P
R
M
E
Site 62
S652
Q
T
S
P
Q
S
A
S
S
P
R
M
E
S
T
Site 63
S653
T
S
P
Q
S
A
S
S
P
R
M
E
S
T
A
Site 64
S658
A
S
S
P
R
M
E
S
T
A
G
I
T
T
T
Site 65
T664
E
S
T
A
G
I
T
T
T
T
S
P
R
T
P
Site 66
T665
S
T
A
G
I
T
T
T
T
S
P
R
T
P
P
Site 67
T666
T
A
G
I
T
T
T
T
S
P
R
T
P
P
P
Site 68
S667
A
G
I
T
T
T
T
S
P
R
T
P
P
P
L
Site 69
T670
T
T
T
T
S
P
R
T
P
P
P
L
T
V
Q
Site 70
T675
P
R
T
P
P
P
L
T
V
Q
D
P
L
C
P
Site 71
S691
V
C
P
L
E
E
L
S
P
D
S
I
D
A
H
Site 72
S694
L
E
E
L
S
P
D
S
I
D
A
H
T
F
D
Site 73
T699
P
D
S
I
D
A
H
T
F
D
F
E
T
I
P
Site 74
T713
P
H
P
N
I
E
Q
T
I
H
Q
V
S
L
D
Site 75
S718
E
Q
T
I
H
Q
V
S
L
D
L
D
S
L
A
Site 76
S723
Q
V
S
L
D
L
D
S
L
A
E
S
P
E
S
Site 77
S727
D
L
D
S
L
A
E
S
P
E
S
D
F
M
S
Site 78
S730
S
L
A
E
S
P
E
S
D
F
M
S
A
V
N
Site 79
S746
F
V
I
E
E
N
L
S
S
P
N
P
I
S
D
Site 80
S747
V
I
E
E
N
L
S
S
P
N
P
I
S
D
P
Site 81
S752
L
S
S
P
N
P
I
S
D
P
Q
S
P
E
M
Site 82
S756
N
P
I
S
D
P
Q
S
P
E
M
M
V
E
S
Site 83
S774
S
V
I
N
A
I
D
S
R
R
M
Q
D
T
N
Site 84
T780
D
S
R
R
M
Q
D
T
N
V
C
G
K
E
D
Site 85
S793
E
D
F
G
D
H
T
S
L
N
V
Q
L
E
R
Site 86
T824
E
D
L
C
H
F
R
T
F
V
Q
K
E
Q
C
Site 87
S834
Q
K
E
Q
C
D
F
S
N
S
L
K
C
T
A
Site 88
S836
E
Q
C
D
F
S
N
S
L
K
C
T
A
V
E
Site 89
T858
V
K
C
S
L
E
I
T
L
K
E
K
H
Q
K
Site 90
S954
E
I
K
E
L
K
Q
S
R
E
I
V
L
E
D
Site 91
S982
L
L
R
A
E
L
Q
S
L
E
Q
S
H
L
K
Site 92
S986
E
L
Q
S
L
E
Q
S
H
L
K
E
L
E
D
Site 93
T994
H
L
K
E
L
E
D
T
L
Q
V
R
H
I
Q
Site 94
T1008
Q
E
F
E
K
V
M
T
D
H
R
V
S
L
E
Site 95
S1013
V
M
T
D
H
R
V
S
L
E
E
L
K
K
E
Site 96
S1051
Q
E
L
K
L
K
V
S
D
L
S
D
T
R
C
Site 97
S1054
K
L
K
V
S
D
L
S
D
T
R
C
K
L
E
Site 98
T1088
S
R
A
Q
Q
K
E
T
L
K
S
L
L
E
Q
Site 99
S1091
Q
Q
K
E
T
L
K
S
L
L
E
Q
E
T
E
Site 100
T1102
Q
E
T
E
N
L
R
T
E
I
S
K
L
N
Q
Site 101
S1105
E
N
L
R
T
E
I
S
K
L
N
Q
K
I
Q
Site 102
S1142
Q
C
I
S
E
L
I
S
R
H
E
E
E
S
N
Site 103
S1148
I
S
R
H
E
E
E
S
N
I
L
K
A
E
L
Site 104
S1160
A
E
L
N
K
V
T
S
L
H
N
Q
A
F
E
Site 105
S1181
E
Q
I
I
E
L
Q
S
K
L
D
S
E
L
S
Site 106
S1185
E
L
Q
S
K
L
D
S
E
L
S
A
L
E
R
Site 107
S1188
S
K
L
D
S
E
L
S
A
L
E
R
Q
K
D
Site 108
Y1205
I
T
Q
Q
E
E
K
Y
E
A
I
I
Q
N
L
Site 109
S1221
K
D
R
Q
K
L
V
S
S
Q
E
Q
D
R
E
Site 110
S1222
D
R
Q
K
L
V
S
S
Q
E
Q
D
R
E
Q
Site 111
T1244
E
K
D
E
A
I
Q
T
A
L
K
E
F
K
L
Site 112
S1274
L
E
N
Q
I
A
K
S
P
A
I
D
S
T
R
Site 113
S1279
A
K
S
P
A
I
D
S
T
R
G
D
S
S
S
Site 114
T1280
K
S
P
A
I
D
S
T
R
G
D
S
S
S
L
Site 115
S1284
I
D
S
T
R
G
D
S
S
S
L
V
A
E
L
Site 116
S1285
D
S
T
R
G
D
S
S
S
L
V
A
E
L
Q
Site 117
S1286
S
T
R
G
D
S
S
S
L
V
A
E
L
Q
E
Site 118
S1323
E
M
Q
N
V
R
T
S
L
I
A
E
Q
Q
T
Site 119
T1334
E
Q
Q
T
N
F
N
T
V
L
T
R
E
K
M
Site 120
S1351
E
N
I
I
N
D
L
S
D
K
L
K
S
T
M
Site 121
S1370
R
D
K
D
L
I
E
S
L
S
E
D
R
A
R
Site 122
S1372
K
D
L
I
E
S
L
S
E
D
R
A
R
L
L
Site 123
S1390
K
K
L
E
E
E
V
S
K
L
R
S
S
S
F
Site 124
S1394
E
E
V
S
K
L
R
S
S
S
F
V
P
S
P
Site 125
S1395
E
V
S
K
L
R
S
S
S
F
V
P
S
P
Y
Site 126
S1396
V
S
K
L
R
S
S
S
F
V
P
S
P
Y
V
Site 127
S1400
R
S
S
S
F
V
P
S
P
Y
V
A
T
A
P
Site 128
S1421
A
P
E
L
P
G
E
S
D
R
S
A
V
E
T
Site 129
S1424
L
P
G
E
S
D
R
S
A
V
E
T
A
D
E
Site 130
T1428
S
D
R
S
A
V
E
T
A
D
E
G
R
V
D
Site 131
S1436
A
D
E
G
R
V
D
S
A
M
E
T
S
M
M
Site 132
T1440
R
V
D
S
A
M
E
T
S
M
M
S
V
Q
E
Site 133
S1482
R
L
N
Q
R
L
M
S
Q
S
M
S
S
V
S
Site 134
S1484
N
Q
R
L
M
S
Q
S
M
S
S
V
S
S
R
Site 135
S1486
R
L
M
S
Q
S
M
S
S
V
S
S
R
H
S
Site 136
S1487
L
M
S
Q
S
M
S
S
V
S
S
R
H
S
E
Site 137
S1489
S
Q
S
M
S
S
V
S
S
R
H
S
E
K
I
Site 138
S1490
Q
S
M
S
S
V
S
S
R
H
S
E
K
I
A
Site 139
S1493
S
S
V
S
S
R
H
S
E
K
I
A
I
R
D
Site 140
Y1518
L
D
E
R
H
D
N
Y
V
L
F
T
V
S
P
Site 141
S1547
L
K
P
G
E
G
A
S
G
A
S
R
R
P
W
Site 142
S1550
G
E
G
A
S
G
A
S
R
R
P
W
V
L
G
Site 143
Y1564
G
K
V
M
E
K
E
Y
C
Q
A
K
K
A
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation