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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
similar to FAT3
Full Name:
Protocadherin Fat 3
Alias:
Cadherin family member 15; CDHF15; FAT tumor suppressor 3; FAT tumor suppressor homolog 3; KIAA1989
Type:
Unknown function
Mass (Da):
505523
Number AA:
4589
UniProt ID:
Q8TDW7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007156
GO:0007275
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S132
Y
L
L
I
V
K
G
S
V
R
G
E
D
L
E
Site 2
Y227
N
Y
D
E
K
N
R
Y
D
L
E
I
L
A
V
Site 3
Y381
I
R
F
E
K
E
V
Y
D
V
S
I
S
E
F
Site 4
S389
D
V
S
I
S
E
F
S
P
P
G
V
V
V
A
Site 5
T565
H
E
S
E
V
N
V
T
I
R
I
G
N
V
N
Site 6
T686
K
S
F
S
C
R
E
T
R
V
A
Q
K
L
A
Site 7
S989
R
F
E
I
D
K
A
S
G
A
I
R
L
S
K
Site 8
S1092
G
S
G
L
G
R
F
S
I
D
D
E
S
G
V
Site 9
S1097
R
F
S
I
D
D
E
S
G
V
I
T
A
A
D
Site 10
Y1495
D
E
K
H
K
L
S
Y
T
V
H
S
S
I
D
Site 11
Y1519
D
P
S
T
G
V
L
Y
T
A
E
R
L
D
H
Site 12
Y1963
K
V
S
D
G
K
F
Y
S
T
S
M
V
T
I
Site 13
S1964
V
S
D
G
K
F
Y
S
T
S
M
V
T
I
M
Site 14
T1965
S
D
G
K
F
Y
S
T
S
M
V
T
I
M
V
Site 15
T1969
F
Y
S
T
S
M
V
T
I
M
V
K
E
A
M
Site 16
T2440
I
L
S
G
N
D
R
T
S
F
L
M
D
S
K
Site 17
S2446
R
T
S
F
L
M
D
S
K
S
G
V
I
T
L
Site 18
S2870
M
E
A
F
N
I
D
S
N
T
G
W
I
S
T
Site 19
Y3099
D
R
E
R
I
P
V
Y
S
L
M
A
K
A
T
Site 20
Y3273
G
T
N
A
E
I
T
Y
L
I
R
S
G
N
E
Site 21
T3867
K
L
A
L
R
L
R
T
L
Q
S
N
G
I
I
Site 22
T3877
S
N
G
I
I
M
Y
T
R
A
N
P
C
I
I
Site 23
Y4044
T
G
L
P
S
G
G
Y
Q
C
T
C
L
S
Q
Site 24
Y4184
K
K
V
F
R
K
N
Y
S
R
N
N
I
T
L
Site 25
S4185
K
V
F
R
K
N
Y
S
R
N
N
I
T
L
V
Site 26
S4215
P
F
R
N
L
R
G
S
G
D
G
R
N
V
Y
Site 27
Y4222
S
G
D
G
R
N
V
Y
Q
E
V
G
P
P
Q
Site 28
Y4237
V
P
V
R
P
M
A
Y
T
P
C
F
Q
S
D
Site 29
T4238
P
V
R
P
M
A
Y
T
P
C
F
Q
S
D
S
Site 30
S4243
A
Y
T
P
C
F
Q
S
D
S
R
S
N
L
D
Site 31
S4245
T
P
C
F
Q
S
D
S
R
S
N
L
D
K
I
Site 32
S4247
C
F
Q
S
D
S
R
S
N
L
D
K
I
V
D
Site 33
T4265
G
E
H
Q
E
M
T
T
F
H
P
E
S
P
R
Site 34
S4270
M
T
T
F
H
P
E
S
P
R
I
L
T
A
R
Site 35
T4275
P
E
S
P
R
I
L
T
A
R
R
G
V
V
V
Site 36
S4293
A
P
N
L
P
A
V
S
P
C
R
S
D
C
D
Site 37
S4297
P
A
V
S
P
C
R
S
D
C
D
S
I
R
K
Site 38
T4311
K
N
G
W
D
A
G
T
E
N
K
G
V
D
D
Site 39
S4328
E
V
T
C
F
A
G
S
N
K
G
S
N
S
E
Site 40
S4332
F
A
G
S
N
K
G
S
N
S
E
V
Q
S
L
Site 41
S4334
G
S
N
K
G
S
N
S
E
V
Q
S
L
S
S
Site 42
S4338
G
S
N
S
E
V
Q
S
L
S
S
F
Q
S
D
Site 43
S4340
N
S
E
V
Q
S
L
S
S
F
Q
S
D
S
G
Site 44
S4341
S
E
V
Q
S
L
S
S
F
Q
S
D
S
G
D
Site 45
S4344
Q
S
L
S
S
F
Q
S
D
S
G
D
D
N
A
Site 46
S4346
L
S
S
F
Q
S
D
S
G
D
D
N
A
S
I
Site 47
S4372
D
T
I
E
N
E
V
S
V
M
D
Q
G
Q
N
Site 48
S4398
W
M
P
G
A
R
L
S
D
I
E
E
V
P
N
Site 49
Y4406
D
I
E
E
V
P
N
Y
E
N
Q
D
G
G
S
Site 50
S4413
Y
E
N
Q
D
G
G
S
A
H
Q
G
S
T
R
Site 51
S4418
G
G
S
A
H
Q
G
S
T
R
E
L
E
S
D
Site 52
S4424
G
S
T
R
E
L
E
S
D
Y
Y
L
G
G
Y
Site 53
Y4426
T
R
E
L
E
S
D
Y
Y
L
G
G
Y
D
I
Site 54
Y4427
R
E
L
E
S
D
Y
Y
L
G
G
Y
D
I
D
Site 55
Y4431
S
D
Y
Y
L
G
G
Y
D
I
D
S
E
Y
P
Site 56
S4435
L
G
G
Y
D
I
D
S
E
Y
P
P
P
H
E
Site 57
Y4437
G
Y
D
I
D
S
E
Y
P
P
P
H
E
E
E
Site 58
S4447
P
H
E
E
E
F
L
S
Q
D
Q
L
P
P
P
Site 59
Y4463
P
E
D
F
P
D
Q
Y
E
A
L
P
P
S
Q
Site 60
S4469
Q
Y
E
A
L
P
P
S
Q
P
V
S
L
A
S
Site 61
S4473
L
P
P
S
Q
P
V
S
L
A
S
T
L
S
P
Site 62
S4476
S
Q
P
V
S
L
A
S
T
L
S
P
D
C
R
Site 63
T4477
Q
P
V
S
L
A
S
T
L
S
P
D
C
R
R
Site 64
S4479
V
S
L
A
S
T
L
S
P
D
C
R
R
R
P
Site 65
S4491
R
R
P
Q
F
H
P
S
Q
Y
L
P
P
H
P
Site 66
Y4493
P
Q
F
H
P
S
Q
Y
L
P
P
H
P
F
P
Site 67
T4503
P
H
P
F
P
N
E
T
D
L
V
G
P
P
A
Site 68
T4516
P
A
S
C
E
F
S
T
F
A
V
S
M
N
Q
Site 69
S4533
E
P
T
G
P
A
D
S
V
S
L
S
L
H
N
Site 70
S4535
T
G
P
A
D
S
V
S
L
S
L
H
N
S
R
Site 71
S4537
P
A
D
S
V
S
L
S
L
H
N
S
R
G
T
Site 72
S4541
V
S
L
S
L
H
N
S
R
G
T
S
S
S
D
Site 73
T4544
S
L
H
N
S
R
G
T
S
S
S
D
V
S
A
Site 74
S4545
L
H
N
S
R
G
T
S
S
S
D
V
S
A
N
Site 75
S4546
H
N
S
R
G
T
S
S
S
D
V
S
A
N
C
Site 76
S4547
N
S
R
G
T
S
S
S
D
V
S
A
N
C
G
Site 77
S4550
G
T
S
S
S
D
V
S
A
N
C
G
F
D
D
Site 78
S4563
D
D
S
E
V
A
M
S
D
Y
E
S
V
G
E
Site 79
Y4565
S
E
V
A
M
S
D
Y
E
S
V
G
E
L
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation