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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SYTL5
Full Name:
Synaptotagmin-like protein 5
Alias:
SLP5
Type:
Membrane protein
Mass (Da):
81523
Number AA:
730
UniProt ID:
Q8TDW5
International Prot ID:
IPI00152647
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0019898
Uniprot
OncoNet
Molecular Function:
GO:0017137
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006886
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
N
S
E
F
I
N
L
S
F
L
L
D
H
E
K
Site 2
Y30
G
V
L
K
R
D
E
Y
L
K
K
V
E
D
K
Site 3
S53
L
L
E
A
K
R
R
S
G
K
T
Q
Q
E
A
Site 4
T56
A
K
R
R
S
G
K
T
Q
Q
E
A
S
R
V
Site 5
T116
I
A
Q
L
R
I
I
T
G
E
W
F
F
E
E
Site 6
S142
G
T
D
V
V
R
Q
S
I
L
R
R
S
P
G
Site 7
S147
R
Q
S
I
L
R
R
S
P
G
A
E
E
V
Q
Site 8
S155
P
G
A
E
E
V
Q
S
Q
E
Q
T
R
Q
D
Site 9
S166
T
R
Q
D
A
E
K
S
D
T
S
P
V
A
G
Site 10
T168
Q
D
A
E
K
S
D
T
S
P
V
A
G
K
K
Site 11
S169
D
A
E
K
S
D
T
S
P
V
A
G
K
K
A
Site 12
S177
P
V
A
G
K
K
A
S
H
D
G
P
K
R
K
Site 13
S189
K
R
K
G
F
L
L
S
K
F
R
S
A
T
R
Site 14
T195
L
S
K
F
R
S
A
T
R
G
E
I
I
T
P
Site 15
T201
A
T
R
G
E
I
I
T
P
K
T
D
T
G
R
Site 16
T204
G
E
I
I
T
P
K
T
D
T
G
R
S
Y
S
Site 17
T206
I
I
T
P
K
T
D
T
G
R
S
Y
S
L
D
Site 18
Y210
K
T
D
T
G
R
S
Y
S
L
D
L
D
G
Q
Site 19
S211
T
D
T
G
R
S
Y
S
L
D
L
D
G
Q
H
Site 20
S221
L
D
G
Q
H
F
R
S
L
K
S
P
P
G
S
Site 21
S224
Q
H
F
R
S
L
K
S
P
P
G
S
D
R
G
Site 22
S228
S
L
K
S
P
P
G
S
D
R
G
S
T
G
S
Site 23
S232
P
P
G
S
D
R
G
S
T
G
S
S
D
L
N
Site 24
T233
P
G
S
D
R
G
S
T
G
S
S
D
L
N
D
Site 25
S235
S
D
R
G
S
T
G
S
S
D
L
N
D
Q
E
Site 26
S236
D
R
G
S
T
G
S
S
D
L
N
D
Q
E
P
Site 27
T247
D
Q
E
P
G
P
R
T
P
K
S
S
R
S
N
Site 28
S250
P
G
P
R
T
P
K
S
S
R
S
N
G
V
T
Site 29
S251
G
P
R
T
P
K
S
S
R
S
N
G
V
T
P
Site 30
S253
R
T
P
K
S
S
R
S
N
G
V
T
P
G
T
Site 31
T257
S
S
R
S
N
G
V
T
P
G
T
Q
S
S
P
Site 32
T260
S
N
G
V
T
P
G
T
Q
S
S
P
A
P
S
Site 33
S262
G
V
T
P
G
T
Q
S
S
P
A
P
S
T
R
Site 34
S263
V
T
P
G
T
Q
S
S
P
A
P
S
T
R
T
Site 35
S267
T
Q
S
S
P
A
P
S
T
R
T
V
T
S
V
Site 36
T268
Q
S
S
P
A
P
S
T
R
T
V
T
S
V
I
Site 37
T270
S
P
A
P
S
T
R
T
V
T
S
V
I
S
R
Site 38
T272
A
P
S
T
R
T
V
T
S
V
I
S
R
E
Y
Site 39
S273
P
S
T
R
T
V
T
S
V
I
S
R
E
Y
G
Site 40
Y279
T
S
V
I
S
R
E
Y
G
F
E
N
S
M
D
Site 41
T298
E
G
T
S
Q
E
L
T
K
S
H
R
R
N
T
Site 42
S300
T
S
Q
E
L
T
K
S
H
R
R
N
T
S
G
Site 43
T305
T
K
S
H
R
R
N
T
S
G
T
P
S
I
A
Site 44
S306
K
S
H
R
R
N
T
S
G
T
P
S
I
A
V
Site 45
T308
H
R
R
N
T
S
G
T
P
S
I
A
V
S
G
Site 46
S310
R
N
T
S
G
T
P
S
I
A
V
S
G
T
S
Site 47
S314
G
T
P
S
I
A
V
S
G
T
S
L
S
S
D
Site 48
T316
P
S
I
A
V
S
G
T
S
L
S
S
D
Q
S
Site 49
S317
S
I
A
V
S
G
T
S
L
S
S
D
Q
S
R
Site 50
S319
A
V
S
G
T
S
L
S
S
D
Q
S
R
S
E
Site 51
S320
V
S
G
T
S
L
S
S
D
Q
S
R
S
E
L
Site 52
S323
T
S
L
S
S
D
Q
S
R
S
E
L
D
L
S
Site 53
S325
L
S
S
D
Q
S
R
S
E
L
D
L
S
E
S
Site 54
S330
S
R
S
E
L
D
L
S
E
S
F
T
E
D
S
Site 55
S332
S
E
L
D
L
S
E
S
F
T
E
D
S
E
D
Site 56
T334
L
D
L
S
E
S
F
T
E
D
S
E
D
T
V
Site 57
S337
S
E
S
F
T
E
D
S
E
D
T
V
S
I
R
Site 58
T340
F
T
E
D
S
E
D
T
V
S
I
R
S
K
S
Site 59
S342
E
D
S
E
D
T
V
S
I
R
S
K
S
V
P
Site 60
S347
T
V
S
I
R
S
K
S
V
P
G
A
L
D
K
Site 61
S356
P
G
A
L
D
K
D
S
L
E
E
T
E
E
S
Site 62
T360
D
K
D
S
L
E
E
T
E
E
S
I
D
A
L
Site 63
S363
S
L
E
E
T
E
E
S
I
D
A
L
V
S
S
Site 64
S369
E
S
I
D
A
L
V
S
S
Q
L
S
T
N
T
Site 65
S370
S
I
D
A
L
V
S
S
Q
L
S
T
N
T
H
Site 66
S373
A
L
V
S
S
Q
L
S
T
N
T
H
R
L
A
Site 67
T374
L
V
S
S
Q
L
S
T
N
T
H
R
L
A
S
Site 68
T376
S
S
Q
L
S
T
N
T
H
R
L
A
S
G
L
Site 69
S381
T
N
T
H
R
L
A
S
G
L
S
T
T
S
L
Site 70
S384
H
R
L
A
S
G
L
S
T
T
S
L
N
S
M
Site 71
S390
L
S
T
T
S
L
N
S
M
M
S
V
Y
S
E
Site 72
S393
T
S
L
N
S
M
M
S
V
Y
S
E
T
G
D
Site 73
Y395
L
N
S
M
M
S
V
Y
S
E
T
G
D
Y
G
Site 74
Y401
V
Y
S
E
T
G
D
Y
G
N
V
K
V
S
G
Site 75
Y424
C
Y
K
T
G
G
L
Y
I
F
V
K
N
C
R
Site 76
Y446
K
K
Q
R
T
D
A
Y
V
K
S
Y
L
L
P
Site 77
Y450
T
D
A
Y
V
K
S
Y
L
L
P
D
K
S
R
Site 78
S456
S
Y
L
L
P
D
K
S
R
N
N
K
R
K
T
Site 79
T463
S
R
N
N
K
R
K
T
K
I
R
T
G
T
N
Site 80
T469
K
T
K
I
R
T
G
T
N
P
E
F
N
E
T
Site 81
T476
T
N
P
E
F
N
E
T
L
K
Y
T
I
S
H
Site 82
Y479
E
F
N
E
T
L
K
Y
T
I
S
H
T
Q
L
Site 83
S482
E
T
L
K
Y
T
I
S
H
T
Q
L
E
T
R
Site 84
T490
H
T
Q
L
E
T
R
T
L
Q
L
S
V
W
H
Site 85
Y498
L
Q
L
S
V
W
H
Y
D
R
F
G
R
N
S
Site 86
S505
Y
D
R
F
G
R
N
S
F
L
G
E
V
E
I
Site 87
T572
E
Q
L
Q
G
N
K
T
F
K
K
G
K
K
K
Site 88
S581
K
K
G
K
K
K
E
S
P
V
I
S
G
G
I
Site 89
T600
I
K
E
A
K
N
L
T
A
V
K
S
G
G
T
Site 90
S604
K
N
L
T
A
V
K
S
G
G
T
S
D
S
F
Site 91
S608
A
V
K
S
G
G
T
S
D
S
F
V
K
G
Y
Site 92
S610
K
S
G
G
T
S
D
S
F
V
K
G
Y
L
L
Site 93
Y615
S
D
S
F
V
K
G
Y
L
L
P
D
D
S
K
Site 94
S621
G
Y
L
L
P
D
D
S
K
A
T
K
H
K
T
Site 95
T628
S
K
A
T
K
H
K
T
L
V
I
K
K
S
V
Site 96
S681
L
G
G
V
R
L
N
S
G
S
G
V
S
H
G
Site 97
S683
G
V
R
L
N
S
G
S
G
V
S
H
G
K
N
Site 98
S696
K
N
V
D
W
M
D
S
Q
G
E
E
Q
R
L
Site 99
T713
K
M
A
N
N
P
G
T
P
F
E
G
V
L
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation