PhosphoNET

           
Protein Info 
   
Short Name:  CABLES1
Full Name:  CDK5 and ABL1 enzyme substrate 1
Alias:  Interactor with CDK3 1
Type:  Adaptor/scaffold
Mass (Da):  67599
Number AA:  633
UniProt ID:  Q8TDN4
International Prot ID:  IPI00291427
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0016538  GO:0005515   PhosphoSite+ KinaseNET
Biological Process:  GO:0007049  GO:0051301  GO:0051726 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S15ATTAACSSGSAGTDA
Site 2S67RRRQAALSFLTNISL
Site 3S109CGARTRFSLLAAAER
Site 4S158PGGHATVSGPGVARG
Site 5S168GVARGFASPLGAGRA
Site 6S176PLGAGRASGEQWQPP
Site 7T229AAFLGSGTPGSGSGS
Site 8S232LGSGTPGSGSGSRGR
Site 9S234SGTPGSGSGSRGRLN
Site 10S236TPGSGSGSRGRLNSF
Site 11S242GSRGRLNSFTQGILP
Site 12T244RGRLNSFTQGILPIA
Site 13S253GILPIAFSRPTSQNY
Site 14T256PIAFSRPTSQNYCSL
Site 15S257IAFSRPTSQNYCSLE
Site 16Y260SRPTSQNYCSLEQPG
Site 17S262PTSQNYCSLEQPGQG
Site 18S271EQPGQGGSTSAFEQL
Site 19S273PGQGGSTSAFEQLQR
Site 20S281AFEQLQRSRRRLISQ
Site 21S287RSRRRLISQRSSLET
Site 22S290RRLISQRSSLETLED
Site 23S291RLISQRSSLETLEDI
Site 24T294SQRSSLETLEDIEEN
Site 25T309APLRRCRTLSGSPRP
Site 26S311LRRCRTLSGSPRPKN
Site 27S313RCRTLSGSPRPKNFK
Site 28T333KNMRQHDTRNGRIVL
Site 29S342NGRIVLISGRRSFCS
Site 30S352RSFCSIFSVLPYRDS
Site 31Y356SIFSVLPYRDSTQVG
Site 32S359SVLPYRDSTQVGDLK
Site 33T360VLPYRDSTQVGDLKL
Site 34S373KLDGGRQSTGAVSLK
Site 35T374LDGGRQSTGAVSLKE
Site 36S378RQSTGAVSLKEIIGL
Site 37T396ELGADGKTVSYTQFL
Site 38S398GADGKTVSYTQFLLP
Site 39T400DGKTVSYTQFLLPTN
Site 40T415AFGARRNTIDSTSSF
Site 41S418ARRNTIDSTSSFSQF
Site 42T419RRNTIDSTSSFSQFR
Site 43S420RNTIDSTSSFSQFRN
Site 44S421NTIDSTSSFSQFRNL
Site 45S423IDSTSSFSQFRNLSH
Site 46S429FSQFRNLSHRSLSIG
Site 47S432FRNLSHRSLSIGRAS
Site 48S434NLSHRSLSIGRASGT
Site 49S439SLSIGRASGTQGSLD
Site 50T441SIGRASGTQGSLDTG
Site 51S444RASGTQGSLDTGSDL
Site 52T447GTQGSLDTGSDLGDF
Site 53S449QGSLDTGSDLGDFMD
Site 54Y457DLGDFMDYDPNLLDD
Site 55Y488YMTTVIDYVKPSDLK
Site 56S492VIDYVKPSDLKKDMN
Site 57T501LKKDMNETFKEKFPH
Site 58T512KFPHIKLTLSKIRSL
Site 59S514PHIKLTLSKIRSLKR
Site 60S518LTLSKIRSLKREMRK
Site 61Y626EHEVMPHYRRLVQSS
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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