PhosphoNET

           
Protein Info 
   
Short Name:  DLG5
Full Name:  Disks large homolog 5
Alias:  Discs large homolog 5; Discs large protein P-dlg; Discs, large 5; KIAA0583; PDLG; P-dlg; Placenta and prostate DLG
Type:  Adaptor/scaffold
Mass (Da):  213868
Number AA:  1919
UniProt ID:  Q8TDM6
International Prot ID:  IPI00411901
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0019898   Uniprot OncoNet
Molecular Function:  GO:0030159     PhosphoSite+ KinaseNET
Biological Process:  GO:0016337  GO:0007242  GO:0008285 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S37LEAAGALSPGERRQL
Site 2S103QPAEGAGSTYSVLST
Site 3T104PAEGAGSTYSVLSTM
Site 4Y105AEGAGSTYSVLSTMP
Site 5S106EGAGSTYSVLSTMPS
Site 6S109GSTYSVLSTMPSDSE
Site 7T110STYSVLSTMPSDSES
Site 8S113SVLSTMPSDSESSSS
Site 9S115LSTMPSDSESSSSLS
Site 10S117TMPSDSESSSSLSSV
Site 11S118MPSDSESSSSLSSVG
Site 12S119PSDSESSSSLSSVGT
Site 13S120SDSESSSSLSSVGTT
Site 14S122SESSSSLSSVGTTGK
Site 15S123ESSSSLSSVGTTGKA
Site 16T126SSLSSVGTTGKAPSP
Site 17T127SLSSVGTTGKAPSPP
Site 18S132GTTGKAPSPPPLLTD
Site 19T138PSPPPLLTDQQVNEK
Site 20T157SIQLRLMTRERNELR
Site 21T171RKRLAFATHGTAFDK
Site 22Y181TAFDKRPYHRLNPDY
Site 23Y188YHRLNPDYERLKIQC
Site 24S200IQCVRAMSDLQSLQN
Site 25S204RAMSDLQSLQNQHTN
Site 26Y226VAKETDFYHTLHSRL
Site 27T228KETDFYHTLHSRLLS
Site 28S231DFYHTLHSRLLSDQT
Site 29S235TLHSRLLSDQTRLKD
Site 30S264ERNLLQQSWEDMKRL
Site 31S295QVLKHNGSSEILNKL
Site 32S296VLKHNGSSEILNKLY
Site 33Y303SEILNKLYDTAMDKL
Site 34T305ILNKLYDTAMDKLEV
Site 35Y317LEVVKKDYDALRKRY
Site 36Y324YDALRKRYSEKVAIH
Site 37S325DALRKRYSEKVAIHN
Site 38S336AIHNADLSRLEQLGE
Site 39T352NQRLLKQTEMLTQQR
Site 40T361MLTQQRDTAIQLQHQ
Site 41S372LQHQCALSLRRFEAI
Site 42S402WEMELLQSELTELRT
Site 43T405ELLQSELTELRTTQV
Site 44T410ELTELRTTQVKTAKE
Site 45T414LRTTQVKTAKESEKY
Site 46Y421TAKESEKYREERDAV
Site 47Y429REERDAVYSEYKLIM
Site 48S430EERDAVYSEYKLIMS
Site 49Y432RDAVYSEYKLIMSER
Site 50S437SEYKLIMSERDQVIS
Site 51S444SERDQVISELDKLQT
Site 52S458TEVELAESKLKSSTS
Site 53S462LAESKLKSSTSEKKA
Site 54S463AESKLKSSTSEKKAA
Site 55S465SKLKSSTSEKKAANE
Site 56T483ALRQIKDTVTMDAGR
Site 57T485RQIKDTVTMDAGRAN
Site 58S539KIVAERDSIRTLCDN
Site 59T542AERDSIRTLCDNLRR
Site 60S556RERDRAVSELAEALR
Site 61S564ELAEALRSLDDTRKQ
Site 62T568ALRSLDDTRKQKNDV
Site 63S576RKQKNDVSRELKELK
Site 64S588ELKEQMESQLEKEAR
Site 65S603FRQLMAHSSHDSAID
Site 66S604RQLMAHSSHDSAIDT
Site 67S607MAHSSHDSAIDTDSM
Site 68T611SHDSAIDTDSMEWET
Site 69S613DSAIDTDSMEWETEV
Site 70T627VVEFERETEDIDLKA
Site 71S711MVVRRRKSLGGKVVT
Site 72S725TPLHINLSGQKDSGI
Site 73S730NLSGQKDSGISLENG
Site 74S754SPAAKEGSLAVGDRI
Site 75S773GIALDNKSLNECESL
Site 76S779KSLNECESLLRSCQD
Site 77S783ECESLLRSCQDSLTL
Site 78S799LLKVFPQSSSWSGQN
Site 79S800LKVFPQSSSWSGQNI
Site 80S801KVFPQSSSWSGQNIF
Site 81S803FPQSSSWSGQNIFEN
Site 82S814IFENIKDSDKMLSFR
Site 83S819KDSDKMLSFRAHGPE
Site 84Y848STQTDIFYTDRLEDR
Site 85S864EPGPPGGSSSFLHKP
Site 86S866GPPGGSSSFLHKPFP
Site 87S886VCPQACPSASERSLS
Site 88S888PQACPSASERSLSSF
Site 89S891CPSASERSLSSFRSD
Site 90S893SASERSLSSFRSDAS
Site 91S894ASERSLSSFRSDASG
Site 92S897RSLSSFRSDASGDRG
Site 93S900SSFRSDASGDRGFGL
Site 94S932PCGVGEASLDKADSE
Site 95S938ASLDKADSEGSNSGG
Site 96S941DKADSEGSNSGGTWP
Site 97S943ADSEGSNSGGTWPKA
Site 98T946EGSNSGGTWPKAMLS
Site 99S953TWPKAMLSSTAVPEK
Site 100T955PKAMLSSTAVPEKLS
Site 101S962TAVPEKLSVYKKPKQ
Site 102Y964VPEKLSVYKKPKQRK
Site 103S972KKPKQRKSIFDPNTF
Site 104T978KSIFDPNTFKRPQTP
Site 105T984NTFKRPQTPPKIDYL
Site 106Y990QTPPKIDYLLPGPGP
Site 107S1000PGPGPAHSPQPSKRA
Site 108S1004PAHSPQPSKRAGPLT
Site 109T1011SKRAGPLTPPKPPRR
Site 110S1019PPKPPRRSDSIKFQH
Site 111S1021KPPRRSDSIKFQHRL
Site 112T1030KFQHRLETSSESEAT
Site 113S1032QHRLETSSESEATLV
Site 114T1037TSSESEATLVGSSPS
Site 115S1041SEATLVGSSPSTSPP
Site 116S1042EATLVGSSPSTSPPS
Site 117S1044TLVGSSPSTSPPSAL
Site 118T1045LVGSSPSTSPPSALP
Site 119S1046VGSSPSTSPPSALPP
Site 120S1049SPSTSPPSALPPDVD
Site 121S1064PGEPMHASPPRKARV
Site 122S1075KARVRIASSYYPEGD
Site 123S1076ARVRIASSYYPEGDG
Site 124Y1077RVRIASSYYPEGDGD
Site 125Y1078VRIASSYYPEGDGDS
Site 126S1085YPEGDGDSSHLPAKK
Site 127S1086PEGDGDSSHLPAKKS
Site 128S1093SHLPAKKSCDEDLTS
Site 129T1099KSCDEDLTSQKVDEL
Site 130S1100SCDEDLTSQKVDELG
Site 131S1115QKRRRPKSAPSFRPK
Site 132S1118RRPKSAPSFRPKLAP
Site 133S1142EQKCVPASGELSPEL
Site 134S1146VPASGELSPELQEWA
Site 135Y1155ELQEWAPYSPGHSSR
Site 136S1156LQEWAPYSPGHSSRH
Site 137S1160APYSPGHSSRHSNPP
Site 138S1161PYSPGHSSRHSNPPL
Site 139S1164PGHSSRHSNPPLYPS
Site 140Y1169RHSNPPLYPSRPSVG
Site 141S1171SNPPLYPSRPSVGTV
Site 142S1174PLYPSRPSVGTVPRS
Site 143T1177PSRPSVGTVPRSLTP
Site 144T1183GTVPRSLTPSTTVSS
Site 145T1186PRSLTPSTTVSSILR
Site 146T1187RSLTPSTTVSSILRN
Site 147S1190TPSTTVSSILRNPIY
Site 148Y1197SILRNPIYTVRSHRV
Site 149T1198ILRNPIYTVRSHRVG
Site 150S1201NPIYTVRSHRVGPCS
Site 151S1208SHRVGPCSSPPAARD
Site 152S1209HRVGPCSSPPAARDA
Site 153S1224GPQGLHPSVQHQGRL
Site 154S1232VQHQGRLSLDLSHRT
Site 155S1236GRLSLDLSHRTCSDY
Site 156T1239SLDLSHRTCSDYSEM
Site 157S1241DLSHRTCSDYSEMRA
Site 158Y1243SHRTCSDYSEMRATH
Site 159S1244HRTCSDYSEMRATHG
Site 160T1249DYSEMRATHGSNSLP
Site 161S1252EMRATHGSNSLPSSA
Site 162S1254RATHGSNSLPSSARL
Site 163S1257HGSNSLPSSARLGSS
Site 164S1258GSNSLPSSARLGSSS
Site 165S1263PSSARLGSSSNLQFK
Site 166S1264SSARLGSSSNLQFKA
Site 167S1265SARLGSSSNLQFKAE
Site 168S1278AERIKIPSTPRYPRS
Site 169T1279ERIKIPSTPRYPRSV
Site 170Y1282KIPSTPRYPRSVVGS
Site 171S1285STPRYPRSVVGSERG
Site 172S1289YPRSVVGSERGSVSH
Site 173S1293VVGSERGSVSHSECS
Site 174S1295GSERGSVSHSECSTP
Site 175S1297ERGSVSHSECSTPPQ
Site 176S1300SVSHSECSTPPQSPL
Site 177T1301VSHSECSTPPQSPLN
Site 178S1305ECSTPPQSPLNIDTL
Site 179T1311QSPLNIDTLSSCSQS
Site 180S1313PLNIDTLSSCSQSQT
Site 181S1314LNIDTLSSCSQSQTS
Site 182S1316IDTLSSCSQSQTSAS
Site 183S1318TLSSCSQSQTSASTL
Site 184T1320SSCSQSQTSASTLPR
Site 185S1321SCSQSQTSASTLPRI
Site 186S1334RIAVNPASLGERRKD
Site 187Y1344ERRKDRPYVEEPRHV
Site 188S1363GSEPLGISIVSGEKG
Site 189Y1373SGEKGGIYVSKVTVG
Site 190T1406GINLRSATEQQARLI
Site 191T1422GQQCDTITILAQYNP
Site 192S1435NPHVHQLSSHSRSSS
Site 193S1436PHVHQLSSHSRSSSH
Site 194S1438VHQLSSHSRSSSHLD
Site 195S1440QLSSHSRSSSHLDPA
Site 196S1441LSSHSRSSSHLDPAG
Site 197S1442SSHSRSSSHLDPAGT
Site 198T1449SHLDPAGTHSTLQGS
Site 199S1451LDPAGTHSTLQGSGT
Site 200T1452DPAGTHSTLQGSGTT
Site 201T1458STLQGSGTTTPEHPS
Site 202T1460LQGSGTTTPEHPSVI
Site 203S1478MEQDEGPSTPPAKQS
Site 204T1479EQDEGPSTPPAKQSS
Site 205S1485STPPAKQSSSRIAGD
Site 206S1486TPPAKQSSSRIAGDA
Site 207S1487PPAKQSSSRIAGDAN
Site 208T1497AGDANKKTLEPRVVF
Site 209S1533VAEVEDDSPAKGPDG
Site 210Y1550PGDLILEYGSLDVRN
Site 211T1559SLDVRNKTVEEVYVE
Site 212Y1564NKTVEEVYVEMLKPR
Site 213Y1580GVRLKVQYRPEEFTK
Site 214T1586QYRPEEFTKAKGLPG
Site 215S1595AKGLPGDSFYIRALY
Site 216Y1597GLPGDSFYIRALYDR
Site 217Y1602SFYIRALYDRLADVE
Site 218S1613ADVEQELSFKKDDIL
Site 219Y1621FKKDDILYVDDTLPQ
Site 220T1625DILYVDDTLPQGTFG
Site 221S1653IQRGQIPSKYVMDQE
Site 222Y1655RGQIPSKYVMDQEFS
Site 223S1662YVMDQEFSRRLSMSE
Site 224S1666QEFSRRLSMSEVKDD
Site 225S1668FSRRLSMSEVKDDNS
Site 226S1675SEVKDDNSATKTLSA
Site 227T1679DDNSATKTLSAAARR
Site 228S1681NSATKTLSAAARRSF
Site 229S1687LSAAARRSFFRRKHK
Site 230S1698RKHKHKRSGSKDGKD
Site 231S1700HKHKRSGSKDGKDLL
Site 232S1716LDAFSSDSIPLFEDS
Site 233S1723SIPLFEDSVSLAYQR
Site 234S1725PLFEDSVSLAYQRVQ
Site 235Y1728EDSVSLAYQRVQKVD
Site 236S1775PLEVMKASQQAIERG
Site 237Y1791KDCLFVDYKRRSGHF
Site 238S1795FVDYKRRSGHFDVTT
Site 239T1801RSGHFDVTTVASIKE
Site 240Y1856KEQRDPIYLRDKVTQ
Site 241T1862IYLRDKVTQRHSKEQ
Site 242S1866DKVTQRHSKEQFEAA
Site 243Y1880AQKLEQEYSRYFTGV
Site 244S1881QKLEQEYSRYFTGVI
Site 245Y1883LEQEYSRYFTGVIQG
Site 246T1885QEYSRYFTGVIQGGA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation