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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DMXL2
Full Name:
DmX-like protein 2
Alias:
Dmx-like 2; KIAA0856; Rabconnectin; Rabconnectin 3; Rabconnectin-3; RC3
Type:
Vesicle protein; Membrane protein, peripheral; Adaptor/scaffold
Mass (Da):
339758
Number AA:
3036
UniProt ID:
Q8TDJ6
International Prot ID:
IPI00152542
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0019898
GO:0008021
Uniprot
OncoNet
Molecular Function:
GO:0017137
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
H
L
H
Q
V
L
T
G
A
V
N
P
G
D
Site 2
Y18
V
N
P
G
D
N
C
Y
S
V
G
S
V
G
D
Site 3
S19
N
P
G
D
N
C
Y
S
V
G
S
V
G
D
V
Site 4
S22
D
N
C
Y
S
V
G
S
V
G
D
V
P
F
T
Site 5
T29
S
V
G
D
V
P
F
T
A
Y
G
S
G
C
D
Site 6
T104
L
K
C
Q
W
L
K
T
G
Q
F
F
L
S
S
Site 7
T127
P
Q
D
N
R
L
L
T
T
T
D
S
I
Q
L
Site 8
T129
D
N
R
L
L
T
T
T
D
S
I
Q
L
W
A
Site 9
S131
R
L
L
T
T
T
D
S
I
Q
L
W
A
P
P
Site 10
T152
E
E
E
E
I
D
N
T
V
P
P
V
L
N
D
Site 11
S178
S
V
H
L
M
E
W
S
P
D
G
E
Y
F
A
Site 12
Y183
E
W
S
P
D
G
E
Y
F
A
T
A
G
K
D
Site 13
T186
P
D
G
E
Y
F
A
T
A
G
K
D
D
C
L
Site 14
S220
H
E
V
K
R
R
Q
S
S
T
Q
F
S
F
V
Site 15
S221
E
V
K
R
R
Q
S
S
T
Q
F
S
F
V
Y
Site 16
T222
V
K
R
R
Q
S
S
T
Q
F
S
F
V
Y
L
Site 17
S225
R
Q
S
S
T
Q
F
S
F
V
Y
L
A
H
P
Site 18
T236
L
A
H
P
R
A
V
T
G
F
S
W
R
K
T
Site 19
S239
P
R
A
V
T
G
F
S
W
R
K
T
S
K
Y
Site 20
T243
T
G
F
S
W
R
K
T
S
K
Y
M
P
R
G
Site 21
S244
G
F
S
W
R
K
T
S
K
Y
M
P
R
G
S
Site 22
Y246
S
W
R
K
T
S
K
Y
M
P
R
G
S
V
C
Site 23
T286
L
G
E
Q
I
C
E
T
T
T
S
S
I
A
S
Site 24
S289
Q
I
C
E
T
T
T
S
S
I
A
S
S
L
S
Site 25
S290
I
C
E
T
T
T
S
S
I
A
S
S
L
S
H
Site 26
S293
T
T
T
S
S
I
A
S
S
L
S
H
A
G
R
Site 27
S294
T
T
S
S
I
A
S
S
L
S
H
A
G
R
H
Site 28
S296
S
S
I
A
S
S
L
S
H
A
G
R
H
K
D
Site 29
S325
L
R
K
G
Q
R
R
S
S
V
L
V
T
H
A
Site 30
S326
R
K
G
Q
R
R
S
S
V
L
V
T
H
A
E
Site 31
T330
R
R
S
S
V
L
V
T
H
A
E
L
M
P
D
Site 32
T339
A
E
L
M
P
D
Q
T
A
M
H
E
V
Q
R
Site 33
S415
M
H
Q
L
R
K
L
S
D
K
Q
V
D
H
E
Site 34
S434
D
R
E
D
E
E
H
S
Q
E
D
R
E
R
G
Site 35
S451
M
K
L
D
H
D
L
S
L
D
R
E
S
E
A
Site 36
S456
D
L
S
L
D
R
E
S
E
A
G
T
G
S
S
Site 37
T460
D
R
E
S
E
A
G
T
G
S
S
E
H
E
D
Site 38
S462
E
S
E
A
G
T
G
S
S
E
H
E
D
G
E
Site 39
S463
S
E
A
G
T
G
S
S
E
H
E
D
G
E
R
Site 40
S473
E
D
G
E
R
E
G
S
P
R
T
Y
S
R
L
Site 41
T476
E
R
E
G
S
P
R
T
Y
S
R
L
S
V
P
Site 42
Y477
R
E
G
S
P
R
T
Y
S
R
L
S
V
P
M
Site 43
S478
E
G
S
P
R
T
Y
S
R
L
S
V
P
M
P
Site 44
S481
P
R
T
Y
S
R
L
S
V
P
M
P
L
P
T
Site 45
T488
S
V
P
M
P
L
P
T
V
L
L
D
R
K
I
Site 46
T500
R
K
I
E
T
L
L
T
E
W
N
K
N
P
D
Site 47
T511
K
N
P
D
M
L
F
T
I
H
P
V
D
G
T
Site 48
Y526
F
L
V
W
H
V
K
Y
L
D
E
Y
N
P
G
Site 49
Y530
H
V
K
Y
L
D
E
Y
N
P
G
I
F
R
Q
Site 50
S556
A
F
P
S
G
D
A
S
S
L
S
K
N
I
M
Site 51
S557
F
P
S
G
D
A
S
S
L
S
K
N
I
M
M
Site 52
S559
S
G
D
A
S
S
L
S
K
N
I
M
M
Y
A
Site 53
S585
L
L
H
Q
E
G
M
S
V
G
S
P
H
G
S
Site 54
S588
Q
E
G
M
S
V
G
S
P
H
G
S
Q
P
H
Site 55
S592
S
V
G
S
P
H
G
S
Q
P
H
S
R
S
H
Site 56
S596
P
H
G
S
Q
P
H
S
R
S
H
S
T
H
M
Site 57
S598
G
S
Q
P
H
S
R
S
H
S
T
H
M
N
I
Site 58
S600
Q
P
H
S
R
S
H
S
T
H
M
N
I
L
A
Site 59
S620
I
S
K
H
I
D
G
S
L
N
Q
W
A
V
T
Site 60
T627
S
L
N
Q
W
A
V
T
F
A
D
K
S
A
F
Site 61
T636
A
D
K
S
A
F
T
T
V
L
T
V
S
H
K
Site 62
T676
S
H
H
N
A
L
L
T
P
E
L
D
C
Q
W
Site 63
S685
E
L
D
C
Q
W
D
S
D
N
K
L
S
R
L
Site 64
T714
L
R
N
A
A
T
R
T
F
H
D
P
N
A
I
Site 65
Y722
F
H
D
P
N
A
I
Y
S
E
L
I
L
W
R
Site 66
S737
V
D
P
I
G
P
L
S
Y
T
G
G
V
S
E
Site 67
S743
L
S
Y
T
G
G
V
S
E
L
A
R
I
N
S
Site 68
S750
S
E
L
A
R
I
N
S
L
H
T
S
A
F
S
Site 69
S754
R
I
N
S
L
H
T
S
A
F
S
N
V
A
W
Site 70
Y793
D
G
K
N
L
R
L
Y
Q
A
V
V
D
A
R
Site 71
S807
R
K
L
L
D
E
L
S
D
P
E
S
S
K
L
Site 72
S811
D
E
L
S
D
P
E
S
S
K
L
I
G
E
V
Site 73
S823
G
E
V
F
N
I
V
S
Q
Q
S
T
A
R
P
Site 74
T873
E
D
M
E
K
K
E
T
E
I
F
F
Q
P
S
Site 75
S880
T
E
I
F
F
Q
P
S
Q
G
Y
R
P
P
P
Site 76
Y883
F
F
Q
P
S
Q
G
Y
R
P
P
P
F
S
E
Site 77
S901
L
V
V
I
E
K
D
S
N
N
N
S
I
L
H
Site 78
S925
Q
A
C
L
A
K
A
S
E
G
A
S
S
E
S
Site 79
S929
A
K
A
S
E
G
A
S
S
E
S
L
L
S
V
Site 80
S930
K
A
S
E
G
A
S
S
E
S
L
L
S
V
P
Site 81
S932
S
E
G
A
S
S
E
S
L
L
S
V
P
G
Q
Site 82
S935
A
S
S
E
S
L
L
S
V
P
G
Q
K
N
V
Site 83
S944
P
G
Q
K
N
V
D
S
S
P
E
T
S
P
S
Site 84
S945
G
Q
K
N
V
D
S
S
P
E
T
S
P
S
V
Site 85
T948
N
V
D
S
S
P
E
T
S
P
S
V
S
P
M
Site 86
S949
V
D
S
S
P
E
T
S
P
S
V
S
P
M
P
Site 87
S951
S
S
P
E
T
S
P
S
V
S
P
M
P
H
S
Site 88
S953
P
E
T
S
P
S
V
S
P
M
P
H
S
S
S
Site 89
S958
S
V
S
P
M
P
H
S
S
S
I
A
N
L
Q
Site 90
S959
V
S
P
M
P
H
S
S
S
I
A
N
L
Q
T
Site 91
S960
S
P
M
P
H
S
S
S
I
A
N
L
Q
T
A
Site 92
S979
L
S
F
R
L
V
Y
S
Q
P
L
D
L
P
E
Site 93
S987
Q
P
L
D
L
P
E
S
V
E
V
I
R
A
T
Site 94
S996
E
V
I
R
A
T
P
S
A
G
H
L
S
S
S
Site 95
S1001
T
P
S
A
G
H
L
S
S
S
S
I
Y
P
V
Site 96
S1040
A
N
P
E
C
N
K
S
D
E
K
E
I
Y
H
Site 97
Y1046
K
S
D
E
K
E
I
Y
H
W
K
R
W
P
L
Site 98
S1062
N
D
E
G
E
D
N
S
S
T
V
S
I
V
G
Site 99
S1063
D
E
G
E
D
N
S
S
T
V
S
I
V
G
R
Site 100
T1064
E
G
E
D
N
S
S
T
V
S
I
V
G
R
P
Site 101
S1066
E
D
N
S
S
T
V
S
I
V
G
R
P
V
A
Site 102
Y1086
T
G
R
L
A
V
A
Y
K
Q
P
I
H
H
N
Site 103
S1115
E
C
E
S
T
G
G
S
E
W
V
L
E
Q
T
Site 104
S1133
D
D
L
V
K
V
G
S
V
L
D
S
R
V
S
Site 105
S1137
K
V
G
S
V
L
D
S
R
V
S
V
D
S
N
Site 106
S1140
S
V
L
D
S
R
V
S
V
D
S
N
L
F
V
Site 107
S1143
D
S
R
V
S
V
D
S
N
L
F
V
Y
S
K
Site 108
S1149
D
S
N
L
F
V
Y
S
K
S
D
A
L
L
S
Site 109
S1151
N
L
F
V
Y
S
K
S
D
A
L
L
S
K
D
Site 110
S1156
S
K
S
D
A
L
L
S
K
D
R
Y
L
I
P
Site 111
Y1160
A
L
L
S
K
D
R
Y
L
I
P
N
I
K
H
Site 112
S1175
L
V
H
L
D
W
V
S
K
E
D
G
S
H
I
Site 113
T1202
G
R
L
S
G
I
V
T
E
Q
T
N
S
K
D
Site 114
T1205
S
G
I
V
T
E
Q
T
N
S
K
D
G
V
A
Site 115
S1228
S
I
K
Q
G
V
K
S
R
W
V
L
L
R
S
Site 116
S1240
L
R
S
I
D
L
V
S
S
V
D
G
T
P
S
Site 117
S1241
R
S
I
D
L
V
S
S
V
D
G
T
P
S
L
Site 118
S1247
S
S
V
D
G
T
P
S
L
P
V
S
L
S
W
Site 119
S1251
G
T
P
S
L
P
V
S
L
S
W
V
R
D
G
Site 120
T1283
H
A
V
K
F
G
D
T
E
A
D
S
S
N
A
Site 121
S1287
F
G
D
T
E
A
D
S
S
N
A
E
E
A
A
Site 122
S1288
G
D
T
E
A
D
S
S
N
A
E
E
A
A
M
Site 123
S1299
E
A
A
M
Q
D
H
S
T
F
K
S
N
M
L
Site 124
T1300
A
A
M
Q
D
H
S
T
F
K
S
N
M
L
A
Site 125
S1303
Q
D
H
S
T
F
K
S
N
M
L
A
R
K
S
Site 126
S1341
F
E
A
A
H
V
L
S
P
T
L
P
Q
Y
H
Site 127
Y1347
L
S
P
T
L
P
Q
Y
H
P
T
Q
L
L
E
Site 128
T1391
D
P
D
A
G
E
G
T
K
R
H
L
S
R
T
Site 129
S1396
E
G
T
K
R
H
L
S
R
T
I
S
V
S
G
Site 130
T1398
T
K
R
H
L
S
R
T
I
S
V
S
G
S
T
Site 131
S1400
R
H
L
S
R
T
I
S
V
S
G
S
T
A
K
Site 132
S1402
L
S
R
T
I
S
V
S
G
S
T
A
K
E
T
Site 133
S1404
R
T
I
S
V
S
G
S
T
A
K
E
T
V
T
Site 134
T1409
S
G
S
T
A
K
E
T
V
T
V
G
K
D
G
Site 135
T1411
S
T
A
K
E
T
V
T
V
G
K
D
G
T
R
Site 136
T1417
V
T
V
G
K
D
G
T
R
D
Y
T
E
I
D
Site 137
Y1420
G
K
D
G
T
R
D
Y
T
E
I
D
S
I
P
Site 138
T1421
K
D
G
T
R
D
Y
T
E
I
D
S
I
P
P
Site 139
S1425
R
D
Y
T
E
I
D
S
I
P
P
L
P
L
Y
Site 140
T1441
L
L
A
A
D
Q
D
T
S
Y
R
I
S
E
E
Site 141
S1442
L
A
A
D
Q
D
T
S
Y
R
I
S
E
E
S
Site 142
Y1443
A
A
D
Q
D
T
S
Y
R
I
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E
E
S
T
Site 143
S1446
Q
D
T
S
Y
R
I
S
E
E
S
T
K
I
P
Site 144
S1449
S
Y
R
I
S
E
E
S
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K
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P
Q
S
Y
Site 145
T1450
Y
R
I
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E
E
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K
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P
Q
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Y
E
Site 146
S1455
E
S
T
K
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P
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E
D
Q
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V
S
Site 147
Y1456
S
T
K
I
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Y
E
D
Q
T
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S
Q
Site 148
T1460
P
Q
S
Y
E
D
Q
T
V
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Q
P
E
D
Q
Site 149
S1462
S
Y
E
D
Q
T
V
S
Q
P
E
D
Q
Y
S
Site 150
Y1468
V
S
Q
P
E
D
Q
Y
S
E
L
F
Q
I
Q
Site 151
S1469
S
Q
P
E
D
Q
Y
S
E
L
F
Q
I
Q
D
Site 152
S1493
P
E
K
R
E
N
K
S
K
V
I
N
L
S
Q
Site 153
S1499
K
S
K
V
I
N
L
S
Q
Y
G
P
A
Y
F
Site 154
Y1501
K
V
I
N
L
S
Q
Y
G
P
A
Y
F
G
Q
Site 155
Y1505
L
S
Q
Y
G
P
A
Y
F
G
Q
E
H
A
R
Site 156
S1515
Q
E
H
A
R
V
L
S
S
H
L
M
H
S
S
Site 157
S1516
E
H
A
R
V
L
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S
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L
M
H
S
S
L
Site 158
S1521
L
S
S
H
L
M
H
S
S
L
P
G
L
T
R
Site 159
S1522
S
S
H
L
M
H
S
S
L
P
G
L
T
R
L
Site 160
S1551
T
S
T
E
L
D
E
S
R
D
K
S
C
S
G
Site 161
S1555
L
D
E
S
R
D
K
S
C
S
G
R
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T
L
Site 162
S1557
E
S
R
D
K
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S
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D
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L
D
E
Site 163
T1561
K
S
C
S
G
R
D
T
L
D
E
C
G
L
R
Site 164
Y1569
L
D
E
C
G
L
R
Y
L
L
A
M
R
L
H
Site 165
Y1587
L
T
S
L
P
P
L
Y
R
V
Q
L
L
H
Q
Site 166
S1656
I
E
K
V
A
K
A
S
F
Q
R
N
N
D
A
Site 167
S1724
G
K
Q
R
F
E
Q
S
A
A
F
F
L
L
A
Site 168
T1764
L
Y
E
S
E
F
E
T
S
S
T
Y
I
S
I
Site 169
S1765
Y
E
S
E
F
E
T
S
S
T
Y
I
S
I
L
Site 170
S1766
E
S
E
F
E
T
S
S
T
Y
I
S
I
L
N
Site 171
T1767
S
E
F
E
T
S
S
T
Y
I
S
I
L
N
Q
Site 172
Y1768
E
F
E
T
S
S
T
Y
I
S
I
L
N
Q
K
Site 173
S1770
E
T
S
S
T
Y
I
S
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L
N
Q
K
I
L
Site 174
S1784
L
G
C
Q
K
D
G
S
G
F
S
C
K
R
L
Site 175
S1787
Q
K
D
G
S
G
F
S
C
K
R
L
H
P
D
Site 176
Y1802
P
F
L
R
S
L
A
Y
W
V
M
K
D
Y
T
Site 177
Y1808
A
Y
W
V
M
K
D
Y
T
R
A
L
D
T
L
Site 178
T1814
D
Y
T
R
A
L
D
T
L
L
E
Q
T
P
K
Site 179
T1819
L
D
T
L
L
E
Q
T
P
K
E
D
D
E
H
Site 180
S1857
L
I
R
R
N
L
A
S
P
E
G
T
L
A
T
Site 181
T1861
N
L
A
S
P
E
G
T
L
A
T
L
G
L
K
Site 182
T1887
I
E
R
K
L
F
F
T
T
A
N
A
H
F
K
Site 183
T1914
K
I
P
K
V
T
K
T
S
A
L
S
A
K
K
Site 184
S1928
K
D
Q
P
D
F
I
S
H
R
M
D
D
V
P
Site 185
S1936
H
R
M
D
D
V
P
S
H
S
K
A
L
S
D
Site 186
S1938
M
D
D
V
P
S
H
S
K
A
L
S
D
G
N
Site 187
S1942
P
S
H
S
K
A
L
S
D
G
N
G
S
S
G
Site 188
S1948
L
S
D
G
N
G
S
S
G
I
E
W
S
N
V
Site 189
S1953
G
S
S
G
I
E
W
S
N
V
T
S
S
Q
Y
Site 190
Y1960
S
N
V
T
S
S
Q
Y
D
W
S
Q
P
I
V
Site 191
S1963
T
S
S
Q
Y
D
W
S
Q
P
I
V
K
V
D
Site 192
S1984
D
W
G
E
D
H
D
S
A
L
D
E
E
E
D
Site 193
S2000
A
V
G
L
V
M
K
S
T
D
A
R
E
K
D
Site 194
T2001
V
G
L
V
M
K
S
T
D
A
R
E
K
D
K
Site 195
S2010
A
R
E
K
D
K
Q
S
D
Q
K
A
S
D
P
Site 196
T2022
S
D
P
N
M
L
L
T
P
Q
E
E
D
D
P
Site 197
T2033
E
D
D
P
E
G
D
T
E
V
D
V
I
A
E
Site 198
Y2062
L
R
T
L
A
T
G
Y
E
V
D
G
G
K
L
Site 199
Y2074
G
K
L
R
F
Q
L
Y
N
W
L
E
K
E
I
Site 200
S2099
S
V
I
K
E
Y
S
S
K
T
Y
S
K
V
E
Site 201
T2101
I
K
E
Y
S
S
K
T
Y
S
K
V
E
S
D
Site 202
Y2102
K
E
Y
S
S
K
T
Y
S
K
V
E
S
D
L
Site 203
S2103
E
Y
S
S
K
T
Y
S
K
V
E
S
D
L
L
Site 204
S2107
K
T
Y
S
K
V
E
S
D
L
L
D
Q
E
E
Site 205
S2123
V
D
K
P
D
I
G
S
Y
E
R
H
Q
I
E
Site 206
Y2124
D
K
P
D
I
G
S
Y
E
R
H
Q
I
E
R
Site 207
S2146
E
H
A
E
R
R
K
S
W
L
Q
K
N
Q
D
Site 208
S2186
L
K
F
L
L
Q
E
S
Q
Q
E
T
T
V
K
Site 209
T2190
L
Q
E
S
Q
Q
E
T
T
V
K
Q
L
Q
S
Site 210
S2197
T
T
V
K
Q
L
Q
S
P
L
P
L
P
T
T
Site 211
Y2235
N
H
I
H
D
I
L
Y
T
I
V
Q
M
K
T
Site 212
T2242
Y
T
I
V
Q
M
K
T
P
P
H
P
S
I
E
Site 213
S2274
I
Y
Q
A
L
C
D
S
H
S
Y
S
Q
T
E
Site 214
S2276
Q
A
L
C
D
S
H
S
Y
S
Q
T
E
G
N
Site 215
S2278
L
C
D
S
H
S
Y
S
Q
T
E
G
N
Q
F
Site 216
T2280
D
S
H
S
Y
S
Q
T
E
G
N
Q
F
T
G
Site 217
S2296
A
Y
Q
G
L
L
L
S
D
R
R
R
L
R
T
Site 218
T2303
S
D
R
R
R
L
R
T
E
S
I
E
E
H
A
Site 219
S2305
R
R
R
L
R
T
E
S
I
E
E
H
A
T
P
Site 220
T2311
E
S
I
E
E
H
A
T
P
N
S
S
P
A
Q
Site 221
S2314
E
E
H
A
T
P
N
S
S
P
A
Q
W
P
G
Site 222
S2315
E
H
A
T
P
N
S
S
P
A
Q
W
P
G
V
Site 223
S2330
S
S
L
I
N
L
L
S
S
A
Q
D
E
D
Q
Site 224
S2365
H
A
L
A
T
N
S
S
S
E
L
F
R
L
A
Site 225
S2399
V
V
K
P
R
R
Q
S
E
N
I
S
A
P
P
Site 226
S2403
R
R
Q
S
E
N
I
S
A
P
P
V
L
S
E
Site 227
S2409
I
S
A
P
P
V
L
S
E
D
I
D
K
H
R
Site 228
T2434
G
R
P
V
K
D
A
T
P
P
P
V
P
A
E
Site 229
S2444
P
V
P
A
E
R
P
S
Y
K
E
K
F
I
P
Site 230
Y2445
V
P
A
E
R
P
S
Y
K
E
K
F
I
P
P
Site 231
S2471
P
F
L
P
L
S
D
S
G
V
I
Y
D
S
D
Site 232
Y2475
L
S
D
S
G
V
I
Y
D
S
D
E
S
I
H
Site 233
S2477
D
S
G
V
I
Y
D
S
D
E
S
I
H
S
D
Site 234
S2480
V
I
Y
D
S
D
E
S
I
H
S
D
E
E
D
Site 235
S2483
D
S
D
E
S
I
H
S
D
E
E
D
D
A
F
Site 236
S2492
E
E
D
D
A
F
F
S
D
T
Q
I
Q
E
H
Site 237
T2494
D
D
A
F
F
S
D
T
Q
I
Q
E
H
Q
D
Site 238
S2506
H
Q
D
P
N
S
Y
S
W
A
L
L
H
L
T
Site 239
Y2571
F
E
G
P
P
P
N
Y
I
N
T
Y
P
T
D
Site 240
T2574
P
P
P
N
Y
I
N
T
Y
P
T
D
L
S
V
Site 241
Y2575
P
P
N
Y
I
N
T
Y
P
T
D
L
S
V
G
Site 242
T2599
A
M
L
E
P
E
N
T
P
F
K
S
R
D
S
Site 243
S2603
P
E
N
T
P
F
K
S
R
D
S
S
A
F
P
Site 244
S2606
T
P
F
K
S
R
D
S
S
A
F
P
V
K
R
Site 245
S2607
P
F
K
S
R
D
S
S
A
F
P
V
K
R
L
Site 246
T2627
K
Q
E
V
L
Q
E
T
F
I
R
Y
I
F
T
Site 247
S2640
F
T
K
K
R
K
Q
S
E
V
E
A
D
L
G
Site 248
Y2648
E
V
E
A
D
L
G
Y
P
G
G
K
A
K
V
Site 249
Y2705
Y
I
W
I
G
E
E
Y
D
R
E
S
K
S
S
Site 250
S2709
G
E
E
Y
D
R
E
S
K
S
S
D
D
V
D
Site 251
S2711
E
Y
D
R
E
S
K
S
S
D
D
V
D
Y
R
Site 252
S2712
Y
D
R
E
S
K
S
S
D
D
V
D
Y
R
G
Site 253
Y2717
K
S
S
D
D
V
D
Y
R
G
S
T
T
T
L
Site 254
S2720
D
D
V
D
Y
R
G
S
T
T
T
L
Y
Q
P
Site 255
T2721
D
V
D
Y
R
G
S
T
T
T
L
Y
Q
P
S
Site 256
T2723
D
Y
R
G
S
T
T
T
L
Y
Q
P
S
A
T
Site 257
Y2725
R
G
S
T
T
T
L
Y
Q
P
S
A
T
S
Y
Site 258
S2728
T
T
T
L
Y
Q
P
S
A
T
S
Y
S
A
S
Site 259
S2731
L
Y
Q
P
S
A
T
S
Y
S
A
S
Q
V
H
Site 260
S2735
S
A
T
S
Y
S
A
S
Q
V
H
P
P
S
S
Site 261
S2741
A
S
Q
V
H
P
P
S
S
L
P
W
L
G
T
Site 262
S2742
S
Q
V
H
P
P
S
S
L
P
W
L
G
T
G
Site 263
T2748
S
S
L
P
W
L
G
T
G
Q
T
S
T
G
A
Site 264
S2756
G
Q
T
S
T
G
A
S
V
L
M
K
R
N
L
Site 265
Y2778
S
H
P
V
H
Q
Y
Y
L
T
G
A
Q
D
G
Site 266
T2780
P
V
H
Q
Y
Y
L
T
G
A
Q
D
G
S
V
Site 267
S2786
L
T
G
A
Q
D
G
S
V
R
M
F
E
W
T
Site 268
T2793
S
V
R
M
F
E
W
T
R
P
Q
Q
L
V
C
Site 269
T2810
Q
A
G
N
A
R
V
T
R
L
Y
F
N
S
Q
Site 270
Y2813
N
A
R
V
T
R
L
Y
F
N
S
Q
G
N
K
Site 271
S2816
V
T
R
L
Y
F
N
S
Q
G
N
K
C
G
V
Site 272
Y2845
T
A
S
N
P
K
P
Y
M
S
W
Q
C
H
S
Site 273
S2856
Q
C
H
S
K
A
T
S
D
F
A
F
I
T
S
Site 274
T2869
T
S
S
S
L
V
A
T
S
G
H
S
N
D
N
Site 275
S2870
S
S
S
L
V
A
T
S
G
H
S
N
D
N
R
Site 276
T2884
R
N
V
C
L
W
D
T
L
I
S
P
G
N
S
Site 277
Y2908
H
G
A
T
V
L
Q
Y
A
P
K
Q
Q
L
L
Site 278
S2917
P
K
Q
Q
L
L
I
S
G
G
R
K
G
H
V
Site 279
T2937
R
Q
R
Q
L
I
H
T
F
Q
A
H
D
S
A
Site 280
Y2953
K
A
L
A
L
D
P
Y
E
E
Y
F
T
T
G
Site 281
Y2956
A
L
D
P
Y
E
E
Y
F
T
T
G
S
A
E
Site 282
T2958
D
P
Y
E
E
Y
F
T
T
G
S
A
E
G
N
Site 283
T2959
P
Y
E
E
Y
F
T
T
G
S
A
E
G
N
I
Site 284
T2972
N
I
K
V
W
R
L
T
G
H
G
L
I
H
S
Site 285
S2979
T
G
H
G
L
I
H
S
F
K
S
E
Y
A
K
Site 286
S2982
G
L
I
H
S
F
K
S
E
Y
A
K
Q
S
I
Site 287
Y2984
I
H
S
F
K
S
E
Y
A
K
Q
S
I
F
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation