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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MAGEE2
Full Name:
Melanoma-associated antigen E2
Alias:
Hepatocellular carcinoma-associated protein 3;MAGE-E2 antigen
Type:
Mass (Da):
60378
Number AA:
523
UniProt ID:
Q8TD90
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
S
Q
N
A
R
H
C
S
A
E
I
T
A
D
Y
Site 2
T16
R
H
C
S
A
E
I
T
A
D
Y
G
D
G
R
Site 3
Y19
S
A
E
I
T
A
D
Y
G
D
G
R
G
E
I
Site 4
T29
G
R
G
E
I
Q
A
T
N
A
S
G
S
P
T
Site 5
S32
E
I
Q
A
T
N
A
S
G
S
P
T
S
M
L
Site 6
S59
N
S
Q
C
V
N
T
S
Q
A
V
Q
D
P
N
Site 7
S76
E
V
L
I
D
E
Q
S
R
R
L
G
A
L
R
Site 8
S92
H
D
P
L
E
D
R
S
I
A
L
V
N
F
M
Site 9
S103
V
N
F
M
R
M
K
S
Q
T
E
G
S
I
Q
Site 10
T105
F
M
R
M
K
S
Q
T
E
G
S
I
Q
Q
S
Site 11
S112
T
E
G
S
I
Q
Q
S
E
M
L
E
F
L
R
Site 12
Y121
M
L
E
F
L
R
E
Y
S
D
Q
F
P
E
I
Site 13
S122
L
E
F
L
R
E
Y
S
D
Q
F
P
E
I
L
Site 14
S133
P
E
I
L
R
R
A
S
A
H
L
D
Q
V
F
Site 15
T153
V
I
D
P
Q
A
D
T
Y
N
L
V
S
K
R
Site 16
Y154
I
D
P
Q
A
D
T
Y
N
L
V
S
K
R
G
Site 17
S158
A
D
T
Y
N
L
V
S
K
R
G
F
Q
I
T
Site 18
T165
S
K
R
G
F
Q
I
T
D
R
I
A
E
S
L
Site 19
S171
I
T
D
R
I
A
E
S
L
D
M
P
K
A
S
Site 20
S198
G
N
R
A
R
E
A
S
I
W
D
L
L
L
K
Site 21
Y242
F
L
E
Y
W
P
V
Y
G
T
N
P
L
E
F
Site 22
S255
E
F
E
F
L
W
G
S
R
A
H
R
E
I
T
Site 23
T262
S
R
A
H
R
E
I
T
K
M
E
A
L
K
F
Site 24
T294
K
A
L
E
G
D
K
T
K
E
R
S
L
T
A
Site 25
S298
G
D
K
T
K
E
R
S
L
T
A
G
L
E
F
Site 26
T300
K
T
K
E
R
S
L
T
A
G
L
E
F
W
S
Site 27
Y378
V
D
T
S
E
H
I
Y
L
L
V
Q
Q
P
E
Site 28
S386
L
L
V
Q
Q
P
E
S
E
E
E
Q
V
M
L
Site 29
T400
L
E
S
L
G
R
P
T
Q
E
Y
V
M
P
I
Site 30
S431
W
N
L
L
R
R
F
S
V
D
V
G
R
K
H
Site 31
S439
V
D
V
G
R
K
H
S
I
T
R
K
L
M
R
Site 32
T441
V
G
R
K
H
S
I
T
R
K
L
M
R
Q
R
Site 33
Y449
R
K
L
M
R
Q
R
Y
L
E
C
R
P
L
S
Site 34
S456
Y
L
E
C
R
P
L
S
Y
S
N
P
V
E
Y
Site 35
Y457
L
E
C
R
P
L
S
Y
S
N
P
V
E
Y
E
Site 36
S458
E
C
R
P
L
S
Y
S
N
P
V
E
Y
E
L
Site 37
Y463
S
Y
S
N
P
V
E
Y
E
L
L
W
G
P
R
Site 38
T475
G
P
R
A
H
H
E
T
I
K
M
K
V
L
E
Site 39
Y483
I
K
M
K
V
L
E
Y
M
A
R
L
Y
R
K
Site 40
Y488
L
E
Y
M
A
R
L
Y
R
K
R
P
Q
N
W
Site 41
S512
D
E
E
A
R
A
K
S
E
A
T
I
M
F
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation