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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPT2
Full Name:
Alanine aminotransferase 2
Alias:
AAT2; ALAT2; ALT2; Glutamic pyruvate transaminase (alanine aminotransferase) 2; Glutamic-alanine transaminase 2; Glutamic-pyruvic transaminase 2; GPT 2
Type:
Transferase; EC 2.6.1.2; Amino Acid Metabolism - alanine, aspartate and glutamate
Mass (Da):
57900
Number AA:
UniProt ID:
Q8TD30
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0004021
GO:0030170
PhosphoSite+
KinaseNET
Biological Process:
GO:0009058
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T16
R
R
G
C
G
P
R
T
P
S
S
W
G
R
S
Site 2
S18
G
C
G
P
R
T
P
S
S
W
G
R
S
Q
S
Site 3
S19
C
G
P
R
T
P
S
S
W
G
R
S
Q
S
S
Site 4
S23
T
P
S
S
W
G
R
S
Q
S
S
A
A
A
E
Site 5
S25
S
S
W
G
R
S
Q
S
S
A
A
A
E
A
S
Site 6
S26
S
W
G
R
S
Q
S
S
A
A
A
E
A
S
A
Site 7
S42
L
K
V
R
P
E
R
S
R
R
E
R
I
L
T
Site 8
T49
S
R
R
E
R
I
L
T
L
E
S
M
N
P
Q
Site 9
S52
E
R
I
L
T
L
E
S
M
N
P
Q
V
K
A
Site 10
Y62
P
Q
V
K
A
V
E
Y
A
V
R
G
P
I
V
Site 11
T88
R
G
I
K
K
P
F
T
E
V
I
R
A
N
I
Site 12
S124
T
Y
P
N
L
L
D
S
P
S
F
P
E
D
A
Site 13
S126
P
N
L
L
D
S
P
S
F
P
E
D
A
K
K
Site 14
S146
L
Q
A
C
G
G
N
S
L
G
S
Y
S
A
S
Site 15
S149
C
G
G
N
S
L
G
S
Y
S
A
S
Q
G
V
Site 16
Y150
G
G
N
S
L
G
S
Y
S
A
S
Q
G
V
N
Site 17
S151
G
N
S
L
G
S
Y
S
A
S
Q
G
V
N
C
Site 18
S153
S
L
G
S
Y
S
A
S
Q
G
V
N
C
I
R
Site 19
Y182
P
A
D
P
D
N
I
Y
L
T
T
G
A
S
D
Site 20
T184
D
P
D
N
I
Y
L
T
T
G
A
S
D
G
I
Site 21
T207
S
G
G
G
K
S
R
T
G
V
M
I
P
I
P
Site 22
Y233
L
D
A
I
Q
V
N
Y
Y
L
D
E
E
N
C
Site 23
Y234
D
A
I
Q
V
N
Y
Y
L
D
E
E
N
C
W
Site 24
Y302
F
L
L
A
D
E
V
Y
Q
D
N
V
Y
S
P
Site 25
Y307
E
V
Y
Q
D
N
V
Y
S
P
D
C
R
F
H
Site 26
S315
S
P
D
C
R
F
H
S
F
K
K
V
L
Y
E
Site 27
Y321
H
S
F
K
K
V
L
Y
E
M
G
P
E
Y
S
Site 28
Y327
L
Y
E
M
G
P
E
Y
S
S
N
V
E
L
A
Site 29
S328
Y
E
M
G
P
E
Y
S
S
N
V
E
L
A
S
Site 30
S335
S
S
N
V
E
L
A
S
F
H
S
T
S
K
G
Site 31
S338
V
E
L
A
S
F
H
S
T
S
K
G
Y
M
G
Site 32
T339
E
L
A
S
F
H
S
T
S
K
G
Y
M
G
E
Site 33
S340
L
A
S
F
H
S
T
S
K
G
Y
M
G
E
C
Site 34
Y353
E
C
G
Y
R
G
G
Y
M
E
V
I
N
L
H
Site 35
S398
P
P
V
A
G
E
E
S
F
E
Q
F
S
R
E
Site 36
S403
E
E
S
F
E
Q
F
S
R
E
K
E
S
V
L
Site 37
Y466
Q
M
A
P
D
M
F
Y
C
M
K
L
L
E
E
Site 38
Y491
F
G
Q
R
E
G
T
Y
H
F
R
M
T
I
L
Site 39
T496
G
T
Y
H
F
R
M
T
I
L
P
P
V
E
K
Site 40
T506
P
P
V
E
K
L
K
T
V
L
Q
K
V
K
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation