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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Bicd2
Full Name:
Protein bicaudal D homolog 2
Alias:
bicaudal D 2; Cytoskeleton-like bicaudal D protein homolog 2; KIAA0699
Type:
Cytoskeletal protein
Mass (Da):
93533
Number AA:
824
UniProt ID:
Q8TD16
International Prot ID:
IPI00178185
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005856
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y10
A
P
S
E
E
E
E
Y
A
R
L
V
M
E
A
Site 2
S30
R
A
E
V
K
R
L
S
H
E
L
A
E
T
T
Site 3
T36
L
S
H
E
L
A
E
T
T
R
E
K
I
Q
A
Site 4
Y68
F
E
E
L
E
V
D
Y
E
A
I
R
S
E
M
Site 5
S73
V
D
Y
E
A
I
R
S
E
M
E
Q
L
K
E
Site 6
S98
K
V
A
A
D
G
E
S
R
E
E
S
L
I
Q
Site 7
S102
D
G
E
S
R
E
E
S
L
I
Q
E
S
A
S
Site 8
S107
E
E
S
L
I
Q
E
S
A
S
K
E
Q
Y
Y
Site 9
Y113
E
S
A
S
K
E
Q
Y
Y
V
R
K
V
L
E
Site 10
Y114
S
A
S
K
E
Q
Y
Y
V
R
K
V
L
E
L
Site 11
T133
K
Q
L
R
N
V
L
T
N
T
Q
S
E
N
E
Site 12
S137
N
V
L
T
N
T
Q
S
E
N
E
R
L
A
S
Site 13
S144
S
E
N
E
R
L
A
S
V
A
Q
E
L
K
E
Site 14
Y181
E
A
R
L
L
Q
D
Y
S
E
L
E
E
E
N
Site 15
S182
A
R
L
L
Q
D
Y
S
E
L
E
E
E
N
I
Site 16
S190
E
L
E
E
E
N
I
S
L
Q
K
Q
V
S
V
Site 17
S196
I
S
L
Q
K
Q
V
S
V
L
R
Q
N
Q
V
Site 18
T219
I
K
R
L
E
E
E
T
E
Y
L
N
S
Q
L
Site 19
Y221
R
L
E
E
E
T
E
Y
L
N
S
Q
L
E
D
Site 20
S224
E
E
T
E
Y
L
N
S
Q
L
E
D
A
I
R
Site 21
S236
A
I
R
L
K
E
I
S
E
R
Q
L
E
E
A
Site 22
T246
Q
L
E
E
A
L
E
T
L
K
T
E
R
E
Q
Site 23
T249
E
A
L
E
T
L
K
T
E
R
E
Q
K
N
S
Site 24
S256
T
E
R
E
Q
K
N
S
L
R
K
E
L
S
H
Site 25
S262
N
S
L
R
K
E
L
S
H
Y
M
S
I
N
D
Site 26
Y264
L
R
K
E
L
S
H
Y
M
S
I
N
D
S
F
Site 27
S266
K
E
L
S
H
Y
M
S
I
N
D
S
F
Y
T
Site 28
Y272
M
S
I
N
D
S
F
Y
T
S
H
L
H
V
S
Site 29
S274
I
N
D
S
F
Y
T
S
H
L
H
V
S
L
D
Site 30
S279
Y
T
S
H
L
H
V
S
L
D
G
L
K
F
S
Site 31
S286
S
L
D
G
L
K
F
S
D
D
A
A
E
P
N
Site 32
T317
K
L
P
L
D
N
K
T
S
T
P
K
K
E
G
Site 33
S318
L
P
L
D
N
K
T
S
T
P
K
K
E
G
L
Site 34
T319
P
L
D
N
K
T
S
T
P
K
K
E
G
L
A
Site 35
S329
K
E
G
L
A
P
P
S
P
S
L
V
S
D
L
Site 36
S331
G
L
A
P
P
S
P
S
L
V
S
D
L
L
S
Site 37
S334
P
P
S
P
S
L
V
S
D
L
L
S
E
L
N
Site 38
S338
S
L
V
S
D
L
L
S
E
L
N
I
S
E
I
Site 39
S343
L
L
S
E
L
N
I
S
E
I
Q
K
L
K
Q
Site 40
T369
L
L
A
T
L
Q
D
T
Q
K
Q
L
E
H
T
Site 41
S379
Q
L
E
H
T
R
G
S
L
S
E
Q
Q
E
K
Site 42
S381
E
H
T
R
G
S
L
S
E
Q
Q
E
K
V
T
Site 43
T391
Q
E
K
V
T
R
L
T
E
N
L
S
A
L
R
Site 44
S395
T
R
L
T
E
N
L
S
A
L
R
R
L
Q
A
Site 45
S403
A
L
R
R
L
Q
A
S
K
E
R
Q
T
A
L
Site 46
T408
Q
A
S
K
E
R
Q
T
A
L
D
N
E
K
D
Site 47
S418
D
N
E
K
D
R
D
S
H
E
D
G
D
Y
Y
Site 48
Y424
D
S
H
E
D
G
D
Y
Y
E
V
D
I
N
G
Site 49
Y425
S
H
E
D
G
D
Y
Y
E
V
D
I
N
G
P
Site 50
S458
E
Q
L
K
A
L
R
S
T
H
E
A
R
E
A
Site 51
T459
Q
L
K
A
L
R
S
T
H
E
A
R
E
A
Q
Site 52
Y474
H
A
E
E
K
G
R
Y
E
A
E
G
Q
A
L
Site 53
T482
E
A
E
G
Q
A
L
T
E
K
V
S
L
L
E
Site 54
S486
Q
A
L
T
E
K
V
S
L
L
E
K
A
S
R
Site 55
S510
E
K
E
L
K
K
V
S
D
V
A
G
E
T
Q
Site 56
S519
V
A
G
E
T
Q
G
S
L
S
V
A
Q
D
E
Site 57
S521
G
E
T
Q
G
S
L
S
V
A
Q
D
E
L
V
Site 58
T529
V
A
Q
D
E
L
V
T
F
S
E
E
L
A
N
Site 59
Y538
S
E
E
L
A
N
L
Y
H
H
V
C
M
C
N
Site 60
Y556
P
N
R
V
M
L
D
Y
Y
R
E
G
Q
G
G
Site 61
Y557
N
R
V
M
L
D
Y
Y
R
E
G
Q
G
G
A
Site 62
T567
G
Q
G
G
A
G
R
T
S
P
G
G
R
T
S
Site 63
S568
Q
G
G
A
G
R
T
S
P
G
G
R
T
S
P
Site 64
S574
T
S
P
G
G
R
T
S
P
E
A
R
G
R
R
Site 65
S582
P
E
A
R
G
R
R
S
P
I
L
L
P
K
G
Site 66
T602
A
G
R
A
D
G
G
T
G
D
S
S
P
S
P
Site 67
S605
A
D
G
G
T
G
D
S
S
P
S
P
G
S
S
Site 68
S606
D
G
G
T
G
D
S
S
P
S
P
G
S
S
L
Site 69
S608
G
T
G
D
S
S
P
S
P
G
S
S
L
P
S
Site 70
S611
D
S
S
P
S
P
G
S
S
L
P
S
P
L
S
Site 71
S612
S
S
P
S
P
G
S
S
L
P
S
P
L
S
D
Site 72
S615
S
P
G
S
S
L
P
S
P
L
S
D
P
R
R
Site 73
S618
S
S
L
P
S
P
L
S
D
P
R
R
E
P
M
Site 74
Y628
R
R
E
P
M
N
I
Y
N
L
I
A
I
I
R
Site 75
T648
L
Q
A
A
V
D
R
T
T
E
L
S
R
Q
R
Site 76
T649
Q
A
A
V
D
R
T
T
E
L
S
R
Q
R
I
Site 77
S652
V
D
R
T
T
E
L
S
R
Q
R
I
A
S
Q
Site 78
S658
L
S
R
Q
R
I
A
S
Q
E
L
G
P
A
V
Site 79
S681
E
E
I
L
K
L
K
S
L
L
S
T
K
R
E
Site 80
S684
L
K
L
K
S
L
L
S
T
K
R
E
Q
I
T
Site 81
T685
K
L
K
S
L
L
S
T
K
R
E
Q
I
T
T
Site 82
T691
S
T
K
R
E
Q
I
T
T
L
R
T
V
L
K
Site 83
T692
T
K
R
E
Q
I
T
T
L
R
T
V
L
K
A
Site 84
T703
V
L
K
A
N
K
Q
T
A
E
V
A
L
A
N
Site 85
S713
V
A
L
A
N
L
K
S
K
Y
E
N
E
K
A
Site 86
Y715
L
A
N
L
K
S
K
Y
E
N
E
K
A
M
V
Site 87
T723
E
N
E
K
A
M
V
T
E
T
M
M
K
L
R
Site 88
T742
A
L
K
E
D
A
A
T
F
S
S
L
R
A
M
Site 89
T752
S
L
R
A
M
F
A
T
R
C
D
E
Y
I
T
Site 90
Y757
F
A
T
R
C
D
E
Y
I
T
Q
L
D
E
M
Site 91
T777
A
A
E
D
E
K
K
T
L
N
S
L
L
R
M
Site 92
S780
D
E
K
K
T
L
N
S
L
L
R
M
A
I
Q
Site 93
T793
I
Q
Q
K
L
A
L
T
Q
R
L
E
L
L
E
Site 94
T817
R
A
K
A
A
P
K
T
K
P
A
T
P
S
L
Site 95
T821
A
P
K
T
K
P
A
T
P
S
L
_
_
_
_
Site 96
S823
K
T
K
P
A
T
P
S
L
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation