KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FBXO25
Full Name:
F-box only protein 25
Alias:
F-box protein 25; F-box protein Fbx25; FBX25
Type:
Mass (Da):
43313
Number AA:
367
UniProt ID:
Q8TCJ0
International Prot ID:
Isoform1 - IPI00289939
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0000151
Uniprot
OncoNet
Molecular Function:
GO:0004842
PhosphoSite+
KinaseNET
Biological Process:
GO:0019941
GO:0016567
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
D
G
W
K
R
C
E
S
C
S
Q
K
L
E
R
Site 2
S29
W
K
R
C
E
S
C
S
Q
K
L
E
R
E
N
Site 3
S44
N
R
C
N
I
S
H
S
I
I
L
N
S
E
D
Site 4
S49
S
H
S
I
I
L
N
S
E
D
G
E
I
F
N
Site 5
Y62
F
N
N
E
E
H
E
Y
A
S
K
K
R
K
K
Site 6
T76
K
D
H
F
R
N
D
T
N
T
Q
S
F
Y
R
Site 7
T78
H
F
R
N
D
T
N
T
Q
S
F
Y
R
E
K
Site 8
Y88
F
Y
R
E
K
W
I
Y
V
H
K
E
S
T
K
Site 9
Y100
S
T
K
E
R
H
G
Y
C
T
L
G
E
A
F
Site 10
T102
K
E
R
H
G
Y
C
T
L
G
E
A
F
N
R
Site 11
S113
A
F
N
R
L
D
F
S
S
A
I
Q
D
I
R
Site 12
S114
F
N
R
L
D
F
S
S
A
I
Q
D
I
R
R
Site 13
Y124
Q
D
I
R
R
F
N
Y
V
V
K
L
L
Q
L
Site 14
S139
I
A
K
S
Q
L
T
S
L
S
G
V
A
Q
K
Site 15
S141
K
S
Q
L
T
S
L
S
G
V
A
Q
K
N
Y
Site 16
Y148
S
G
V
A
Q
K
N
Y
F
N
I
L
D
K
I
Site 17
T227
K
Q
V
N
N
G
L
T
L
S
D
L
P
L
H
Site 18
Y241
H
M
L
N
N
I
L
Y
R
F
S
D
G
W
D
Site 19
T251
S
D
G
W
D
I
I
T
L
G
Q
V
T
P
T
Site 20
T258
T
L
G
Q
V
T
P
T
L
Y
M
L
S
E
D
Site 21
Y260
G
Q
V
T
P
T
L
Y
M
L
S
E
D
R
Q
Site 22
S263
T
P
T
L
Y
M
L
S
E
D
R
Q
L
W
K
Site 23
Y300
H
I
E
W
K
L
M
Y
F
A
L
Q
K
H
Y
Site 24
Y307
Y
F
A
L
Q
K
H
Y
P
A
K
E
Q
Y
G
Site 25
T345
K
D
S
G
H
P
C
T
A
A
D
P
D
S
C
Site 26
S351
C
T
A
A
D
P
D
S
C
F
T
P
V
S
P
Site 27
T354
A
D
P
D
S
C
F
T
P
V
S
P
Q
H
F
Site 28
S357
D
S
C
F
T
P
V
S
P
Q
H
F
I
D
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation