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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CIP2A
Full Name:
Protein CIP2A
Alias:
Protein CIP2A
Type:
Mass (Da):
102185
Number AA:
905
UniProt ID:
Q8TCG1
International Prot ID:
IPI00154283
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0016021
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005515
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
K
S
L
L
L
T
V
S
Q
Y
K
A
V
K
S
Site 2
Y17
L
L
L
T
V
S
Q
Y
K
A
V
K
S
E
A
Site 3
S22
S
Q
Y
K
A
V
K
S
E
A
N
A
T
Q
L
Site 4
T46
Q
K
L
T
R
L
F
T
S
N
Q
I
L
T
S
Site 5
S47
K
L
T
R
L
F
T
S
N
Q
I
L
T
S
E
Site 6
Y97
R
D
C
L
Q
N
T
Y
N
L
N
S
V
L
A
Site 7
Y129
Q
L
L
Q
K
L
T
Y
N
V
K
I
F
Y
S
Site 8
S154
L
I
D
H
I
Q
S
S
E
D
E
L
K
M
P
Site 9
T182
S
V
Q
T
H
I
K
T
L
S
N
V
K
S
F
Site 10
S184
Q
T
H
I
K
T
L
S
N
V
K
S
F
Y
R
Site 11
S188
K
T
L
S
N
V
K
S
F
Y
R
T
L
I
T
Site 12
T234
H
A
R
N
I
H
Q
T
F
Q
L
I
F
N
I
Site 13
T248
I
L
I
N
G
D
G
T
L
T
R
K
Y
S
V
Site 14
T250
I
N
G
D
G
T
L
T
R
K
Y
S
V
D
L
Site 15
Y253
D
G
T
L
T
R
K
Y
S
V
D
L
L
M
D
Site 16
Y270
K
N
P
K
I
A
D
Y
L
T
R
Y
E
H
F
Site 17
T272
P
K
I
A
D
Y
L
T
R
Y
E
H
F
S
S
Site 18
Y274
I
A
D
Y
L
T
R
Y
E
H
F
S
S
C
L
Site 19
S279
T
R
Y
E
H
F
S
S
C
L
H
Q
V
L
G
Site 20
S295
L
N
G
K
D
P
D
S
S
S
K
V
L
E
L
Site 21
S296
N
G
K
D
P
D
S
S
S
K
V
L
E
L
L
Site 22
S297
G
K
D
P
D
S
S
S
K
V
L
E
L
L
L
Site 23
T317
T
Q
L
R
H
M
L
T
Q
M
M
F
E
Q
S
Site 24
S324
T
Q
M
M
F
E
Q
S
P
P
G
S
A
T
L
Site 25
S328
F
E
Q
S
P
P
G
S
A
T
L
G
S
H
T
Site 26
T330
Q
S
P
P
G
S
A
T
L
G
S
H
T
K
C
Site 27
S333
P
G
S
A
T
L
G
S
H
T
K
C
L
E
P
Site 28
T335
S
A
T
L
G
S
H
T
K
C
L
E
P
T
V
Site 29
S349
V
A
L
L
R
W
L
S
Q
P
L
D
G
S
E
Site 30
S355
L
S
Q
P
L
D
G
S
E
N
C
S
V
L
A
Site 31
T442
H
I
A
K
I
L
T
T
V
K
C
T
T
L
I
Site 32
T454
T
L
I
E
Q
Q
F
T
Y
G
K
I
D
L
G
Site 33
Y501
P
G
M
E
V
S
F
Y
K
I
L
Q
D
P
R
Site 34
S519
P
L
A
F
A
L
T
S
D
N
R
E
Q
V
Q
Site 35
S527
D
N
R
E
Q
V
Q
S
G
L
R
I
L
L
E
Site 36
S572
P
R
K
M
P
W
Q
S
S
N
H
S
F
P
T
Site 37
S573
R
K
M
P
W
Q
S
S
N
H
S
F
P
T
S
Site 38
S576
P
W
Q
S
S
N
H
S
F
P
T
S
I
K
C
Site 39
S580
S
N
H
S
F
P
T
S
I
K
C
L
T
P
H
Site 40
T585
P
T
S
I
K
C
L
T
P
H
L
K
D
G
V
Site 41
S631
D
V
Y
E
M
K
L
S
T
L
A
S
K
E
S
Site 42
T632
V
Y
E
M
K
L
S
T
L
A
S
K
E
S
R
Site 43
S635
M
K
L
S
T
L
A
S
K
E
S
R
L
Q
D
Site 44
S638
S
T
L
A
S
K
E
S
R
L
Q
D
L
L
E
Site 45
T670
C
Q
R
T
Q
A
E
T
E
A
R
T
L
A
S
Site 46
S677
T
E
A
R
T
L
A
S
M
L
R
E
V
E
R
Site 47
S700
L
K
A
Q
Q
V
E
S
E
R
A
Q
S
D
I
Site 48
S705
V
E
S
E
R
A
Q
S
D
I
E
H
L
F
Q
Site 49
S719
Q
H
N
R
K
L
E
S
V
A
E
E
H
E
I
Site 50
S730
E
H
E
I
L
T
K
S
Y
M
E
L
L
Q
R
Site 51
S740
E
L
L
Q
R
N
E
S
T
E
K
K
N
K
D
Site 52
S754
D
L
Q
I
T
C
D
S
L
N
K
Q
I
E
T
Site 53
T761
S
L
N
K
Q
I
E
T
V
K
K
L
N
E
S
Site 54
S776
L
K
E
Q
N
E
K
S
I
A
Q
L
I
E
K
Site 55
T817
V
Q
E
E
K
I
K
T
L
Q
K
E
R
E
D
Site 56
S837
D
I
L
R
K
E
L
S
R
T
E
Q
I
R
K
Site 57
T839
L
R
K
E
L
S
R
T
E
Q
I
R
K
E
L
Site 58
S847
E
Q
I
R
K
E
L
S
I
K
A
S
S
L
E
Site 59
S851
K
E
L
S
I
K
A
S
S
L
E
V
Q
K
A
Site 60
S869
G
R
L
E
E
K
E
S
L
V
K
L
Q
Q
E
Site 61
T900
G
G
K
I
N
P
E
T
V
N
L
S
I
_
_
Site 62
S904
N
P
E
T
V
N
L
S
I
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation