KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
C2orf65
Full Name:
Uncharacterized protein C2orf65
Alias:
Type:
Mass (Da):
59386
Number AA:
530
UniProt ID:
Q8TC57
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
H
P
G
R
T
T
G
K
G
P
S
T
H
Site 2
S62
L
M
G
P
S
R
M
S
L
F
S
L
Y
M
V
Site 3
S65
P
S
R
M
S
L
F
S
L
Y
M
V
Q
D
Q
Site 4
Y67
R
M
S
L
F
S
L
Y
M
V
Q
D
Q
H
E
Site 5
T91
G
N
F
A
R
L
Q
T
C
I
S
E
L
R
M
Site 6
S94
A
R
L
Q
T
C
I
S
E
L
R
M
L
Q
R
Site 7
S107
Q
R
E
G
C
F
R
S
Q
G
A
S
L
R
L
Site 8
S111
C
F
R
S
Q
G
A
S
L
R
L
A
V
E
D
Site 9
Y126
G
L
Q
Q
F
K
Q
Y
S
R
H
V
T
T
R
Site 10
T131
K
Q
Y
S
R
H
V
T
T
R
A
A
L
T
Y
Site 11
T144
T
Y
T
S
L
E
I
T
I
L
T
S
Q
P
G
Site 12
S188
G
I
L
E
H
V
D
S
A
S
P
V
E
D
T
Site 13
S190
L
E
H
V
D
S
A
S
P
V
E
D
T
S
N
Site 14
T195
S
A
S
P
V
E
D
T
S
N
D
E
S
S
I
Site 15
S196
A
S
P
V
E
D
T
S
N
D
E
S
S
I
L
Site 16
S200
E
D
T
S
N
D
E
S
S
I
L
G
T
D
I
Site 17
S201
D
T
S
N
D
E
S
S
I
L
G
T
D
I
D
Site 18
T205
D
E
S
S
I
L
G
T
D
I
D
L
Q
T
I
Site 19
T211
G
T
D
I
D
L
Q
T
I
D
N
D
I
V
S
Site 20
S247
L
L
S
S
Q
C
F
S
N
I
S
R
P
R
D
Site 21
S280
L
A
G
T
A
D
G
S
L
R
M
D
D
P
K
Site 22
T292
D
P
K
G
D
F
I
T
L
Y
Q
M
A
S
Q
Site 23
Y294
K
G
D
F
I
T
L
Y
Q
M
A
S
Q
S
S
Site 24
S298
I
T
L
Y
Q
M
A
S
Q
S
S
A
S
H
Y
Site 25
S300
L
Y
Q
M
A
S
Q
S
S
A
S
H
Y
K
L
Site 26
Y305
S
Q
S
S
A
S
H
Y
K
L
Q
V
I
K
A
Site 27
S321
K
S
S
G
L
C
E
S
L
T
Y
G
L
P
F
Site 28
S376
E
P
P
G
P
G
H
S
Q
R
I
P
A
S
T
Site 29
T410
R
E
L
M
L
P
S
T
F
P
L
L
P
E
D
Site 30
S422
P
E
D
P
H
D
D
S
L
K
N
V
E
S
M
Site 31
S428
D
S
L
K
N
V
E
S
M
L
D
S
L
E
L
Site 32
S432
N
V
E
S
M
L
D
S
L
E
L
E
P
T
Y
Site 33
T438
D
S
L
E
L
E
P
T
Y
N
P
L
H
V
Q
Site 34
Y439
S
L
E
L
E
P
T
Y
N
P
L
H
V
Q
S
Site 35
S446
Y
N
P
L
H
V
Q
S
H
L
Y
S
H
L
S
Site 36
Y449
L
H
V
Q
S
H
L
Y
S
H
L
S
S
I
Y
Site 37
S450
H
V
Q
S
H
L
Y
S
H
L
S
S
I
Y
A
Site 38
S453
S
H
L
Y
S
H
L
S
S
I
Y
A
K
P
Q
Site 39
S454
H
L
Y
S
H
L
S
S
I
Y
A
K
P
Q
G
Site 40
Y456
Y
S
H
L
S
S
I
Y
A
K
P
Q
G
R
L
Site 41
S469
R
L
H
P
H
W
E
S
R
A
P
R
K
H
P
Site 42
T490
Q
T
N
R
A
R
A
T
V
A
P
L
P
M
T
Site 43
S504
T
P
V
P
G
R
A
S
K
M
P
A
A
S
K
Site 44
S510
A
S
K
M
P
A
A
S
K
S
S
S
D
A
F
Site 45
S512
K
M
P
A
A
S
K
S
S
S
D
A
F
F
L
Site 46
S514
P
A
A
S
K
S
S
S
D
A
F
F
L
P
S
Site 47
S521
S
D
A
F
F
L
P
S
E
W
E
K
D
P
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation