PhosphoNET

           
Protein Info 
   
Short Name:  DEPDC6
Full Name:  DEP domain-containing mTOR-interacting protein
Alias:  DEP domain containing 6; DEP domain-containing protein 6; DEP.6; DEPD6; FLJ12428
Type: 
Mass (Da):  46294
Number AA:  409
UniProt ID:  Q8TB45
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005622     Uniprot OncoNet
Molecular Function:  GO:0005515     PhosphoSite+ KinaseNET
Biological Process:  GO:0007242  GO:0032007  GO:0045792 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S6__MEEGGSTGSAGSD
Site 2T7_MEEGGSTGSAGSDS
Site 3S9EEGGSTGSAGSDSST
Site 4S12GSTGSAGSDSSTSGS
Site 5S14TGSAGSDSSTSGSGG
Site 6S15GSAGSDSSTSGSGGA
Site 7T16SAGSDSSTSGSGGAQ
Site 8S17AGSDSSTSGSGGAQQ
Site 9S19SDSSTSGSGGAQQRE
Site 10T36RMAEVLVTGEQLRLR
Site 11Y60RRHHLKTYPNCFVAK
Site 12S80LIEHKEASDRETAIK
Site 13T84KEASDRETAIKLMQK
Site 14T123RFRKDDGTFPLDNEV
Site 15Y140FMRGQRLYEKLMSPE
Site 16S145RLYEKLMSPENTLLQ
Site 17T149KLMSPENTLLQPREE
Site 18Y161REEEGVKYERTFMAS
Site 19T164EGVKYERTFMASEFL
Site 20S168YERTFMASEFLDWLV
Site 21T181LVQEGEATTRKEAEQ
Site 22Y215FVDSNLLYQFRMNFR
Site 23S235MELLNEKSPSSQETH
Site 24S237LLNEKSPSSQETHDS
Site 25S238LNEKSPSSQETHDSP
Site 26T241KSPSSQETHDSPFCL
Site 27S244SSQETHDSPFCLRKQ
Site 28S252PFCLRKQSHDNRKST
Site 29S258QSHDNRKSTSFMSVS
Site 30T259SHDNRKSTSFMSVSP
Site 31S260HDNRKSTSFMSVSPS
Site 32S263RKSTSFMSVSPSKEI
Site 33S265STSFMSVSPSKEIKI
Site 34S267SFMSVSPSKEIKIVS
Site 35S274SKEIKIVSAVRRSSM
Site 36S279IVSAVRRSSMSSCGS
Site 37S280VSAVRRSSMSSCGSS
Site 38S282AVRRSSMSSCGSSGY
Site 39S283VRRSSMSSCGSSGYF
Site 40S286SSMSSCGSSGYFSSS
Site 41S287SMSSCGSSGYFSSSP
Site 42Y289SSCGSSGYFSSSPTL
Site 43S291CGSSGYFSSSPTLSS
Site 44S292GSSGYFSSSPTLSSS
Site 45S293SSGYFSSSPTLSSSP
Site 46T295GYFSSSPTLSSSPPV
Site 47S297FSSSPTLSSSPPVLC
Site 48S298SSSPTLSSSPPVLCN
Site 49S299SSPTLSSSPPVLCNP
Site 50S308PVLCNPKSVLKRPVT
Site 51T315SVLKRPVTSEELLTP
Site 52T321VTSEELLTPGAPYAR
Site 53T330GAPYARKTFTIVGDA
Site 54T387VLHVDYRTVSNLILT
Site 55S389HVDYRTVSNLILTGP
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation