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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF420
Full Name:
Zinc finger protein 420
Alias:
APAK; ATM and p53-associated KZNF protein; FLJ32191; Zinc finger 420; ZN420
Type:
Intracellular, Nucleus protein
Mass (Da):
80247
Number AA:
688
UniProt ID:
Q8TAQ5
International Prot ID:
IPI00154558
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
R
D
V
A
I
D
F
S
Q
E
E
W
E
C
L
Site 2
S25
E
E
W
E
C
L
D
S
A
Q
R
D
L
Y
R
Site 3
Y31
D
S
A
Q
R
D
L
Y
R
D
V
M
L
E
N
Site 4
Y39
R
D
V
M
L
E
N
Y
S
N
L
V
S
L
D
Site 5
S40
D
V
M
L
E
N
Y
S
N
L
V
S
L
D
L
Site 6
S44
E
N
Y
S
N
L
V
S
L
D
L
P
S
R
C
Site 7
S53
D
L
P
S
R
C
A
S
K
D
L
S
P
E
K
Site 8
S57
R
C
A
S
K
D
L
S
P
E
K
N
T
Y
E
Site 9
Y63
L
S
P
E
K
N
T
Y
E
T
E
L
S
Q
W
Site 10
S68
N
T
Y
E
T
E
L
S
Q
W
E
M
S
D
R
Site 11
S73
E
L
S
Q
W
E
M
S
D
R
L
E
N
C
D
Site 12
S86
C
D
L
E
E
S
N
S
R
D
Y
L
E
A
K
Site 13
Y89
E
E
S
N
S
R
D
Y
L
E
A
K
G
K
M
Site 14
Y106
Q
Q
E
N
Q
K
E
Y
F
R
Q
G
M
I
I
Site 15
Y125
S
I
F
N
Q
H
T
Y
L
S
Q
H
S
R
C
Site 16
S130
H
T
Y
L
S
Q
H
S
R
C
H
S
T
E
K
Site 17
S134
S
Q
H
S
R
C
H
S
T
E
K
P
Y
K
C
Site 18
Y139
C
H
S
T
E
K
P
Y
K
C
K
E
C
G
K
Site 19
S152
G
K
A
F
R
R
A
S
H
L
T
Q
H
Q
S
Site 20
T155
F
R
R
A
S
H
L
T
Q
H
Q
S
I
H
T
Site 21
T162
T
Q
H
Q
S
I
H
T
G
E
K
P
Y
E
C
Site 22
Y167
I
H
T
G
E
K
P
Y
E
C
K
Q
C
G
K
Site 23
S177
K
Q
C
G
K
A
F
S
R
D
S
Q
L
S
L
Site 24
S180
G
K
A
F
S
R
D
S
Q
L
S
L
H
Q
R
Site 25
S183
F
S
R
D
S
Q
L
S
L
H
Q
R
L
H
T
Site 26
T190
S
L
H
Q
R
L
H
T
G
E
K
P
Y
A
C
Site 27
Y195
L
H
T
G
E
K
P
Y
A
C
K
E
C
G
K
Site 28
T205
K
E
C
G
K
A
F
T
Q
S
S
Q
L
I
L
Site 29
S208
G
K
A
F
T
Q
S
S
Q
L
I
L
H
H
R
Site 30
T218
I
L
H
H
R
I
H
T
G
E
K
P
Y
K
C
Site 31
Y223
I
H
T
G
E
K
P
Y
K
C
E
E
C
G
K
Site 32
S236
G
K
A
F
I
R
S
S
Q
L
T
R
H
Q
K
Site 33
T239
F
I
R
S
S
Q
L
T
R
H
Q
K
V
H
T
Site 34
T246
T
R
H
Q
K
V
H
T
G
E
K
P
Y
E
C
Site 35
Y251
V
H
T
G
E
K
P
Y
E
C
K
E
C
G
K
Site 36
S264
G
K
A
F
T
Q
N
S
Q
L
T
L
H
Q
R
Site 37
T267
F
T
Q
N
S
Q
L
T
L
H
Q
R
L
H
T
Site 38
T274
T
L
H
Q
R
L
H
T
G
E
K
L
Y
E
C
Site 39
Y279
L
H
T
G
E
K
L
Y
E
C
K
E
C
R
K
Site 40
S292
R
K
V
F
T
Q
L
S
Q
L
I
L
H
K
R
Site 41
T302
I
L
H
K
R
I
H
T
G
E
K
P
Y
E
C
Site 42
Y307
I
H
T
G
E
K
P
Y
E
C
K
E
C
G
K
Site 43
S320
G
K
A
F
I
C
G
S
Q
L
S
Q
H
Q
K
Site 44
Y335
I
H
N
G
E
K
P
Y
E
C
K
E
C
G
R
Site 45
S348
G
R
A
F
I
R
G
S
L
L
M
Q
H
Q
R
Site 46
T358
M
Q
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 47
S376
G
K
A
F
I
R
G
S
Q
L
T
Q
H
Q
R
Site 48
T379
F
I
R
G
S
Q
L
T
Q
H
Q
R
I
H
T
Site 49
T386
T
Q
H
Q
R
I
H
T
N
E
K
P
Y
E
C
Site 50
Y391
I
H
T
N
E
K
P
Y
E
C
K
E
C
G
K
Site 51
S401
K
E
C
G
K
M
F
S
H
G
S
Q
L
T
Q
Site 52
S404
G
K
M
F
S
H
G
S
Q
L
T
Q
H
Q
R
Site 53
T414
T
Q
H
Q
R
I
H
T
G
E
K
P
Y
Q
C
Site 54
Y419
I
H
T
G
E
K
P
Y
Q
C
K
E
C
G
K
Site 55
S432
G
K
A
F
N
R
G
S
L
L
T
R
H
Q
R
Site 56
T435
F
N
R
G
S
L
L
T
R
H
Q
R
I
H
T
Site 57
T442
T
R
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 58
T455
E
C
K
E
C
G
K
T
F
S
R
G
S
E
L
Site 59
S457
K
E
C
G
K
T
F
S
R
G
S
E
L
T
Q
Site 60
S460
G
K
T
F
S
R
G
S
E
L
T
Q
H
E
R
Site 61
T463
F
S
R
G
S
E
L
T
Q
H
E
R
I
H
T
Site 62
T470
T
Q
H
E
R
I
H
T
G
E
K
P
Y
E
C
Site 63
S483
E
C
K
E
C
G
K
S
F
I
R
G
S
Q
L
Site 64
S488
G
K
S
F
I
R
G
S
Q
L
T
Q
H
Q
R
Site 65
T498
T
Q
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 66
Y503
I
H
T
G
E
K
P
Y
E
C
K
E
C
R
M
Site 67
T513
K
E
C
R
M
A
F
T
Q
S
S
H
L
S
Q
Site 68
S519
F
T
Q
S
S
H
L
S
Q
H
Q
R
L
H
T
Site 69
T526
S
Q
H
Q
R
L
H
T
G
E
K
P
Y
V
C
Site 70
Y531
L
H
T
G
E
K
P
Y
V
C
N
E
C
G
K
Site 71
T554
I
Q
H
Q
R
I
H
T
G
E
K
P
Y
Q
C
Site 72
S597
K
E
C
G
K
A
F
S
H
G
S
Q
L
T
L
Site 73
S600
G
K
A
F
S
H
G
S
Q
L
T
L
H
Q
R
Site 74
T603
F
S
H
G
S
Q
L
T
L
H
Q
R
I
H
T
Site 75
T610
T
L
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 76
Y615
I
H
T
G
E
K
P
Y
E
C
R
E
C
R
K
Site 77
T625
R
E
C
R
K
A
F
T
Q
S
S
H
L
S
R
Site 78
S627
C
R
K
A
F
T
Q
S
S
H
L
S
R
H
Q
Site 79
S628
R
K
A
F
T
Q
S
S
H
L
S
R
H
Q
R
Site 80
S631
F
T
Q
S
S
H
L
S
R
H
Q
R
I
H
T
Site 81
T638
S
R
H
Q
R
I
H
T
G
E
K
P
Y
Q
C
Site 82
S656
G
K
A
F
T
R
G
S
Q
L
T
Q
H
Q
R
Site 83
T659
F
T
R
G
S
Q
L
T
Q
H
Q
R
I
H
I
Site 84
S670
R
I
H
I
S
E
K
S
F
E
Y
K
E
C
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation