PhosphoNET

           
Protein Info 
   
Short Name:  KEPI
Full Name:  Protein phosphatase 1 regulatory subunit 14C
Alias:  Kinase-enhanced PP1 inhibitor; PKC-potentiated PP1 inhibitory protein; Serologically defined breast cancer antigen NY-BR-81
Type:  Membrane, Cytoplasm protein
Mass (Da):  17843
Number AA:  165
UniProt ID:  Q8TAE6
International Prot ID:  IPI00290397
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0019898   Uniprot OncoNet
Molecular Function:  GO:0005515     PhosphoSite+ KinaseNET
Biological Process:  GO:0042325     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S25GARVFFQSPRGGAGG
Site 2S33PRGGAGGSPGSSSGS
Site 3S36GAGGSPGSSSGSGSS
Site 4S37AGGSPGSSSGSGSSR
Site 5S38GGSPGSSSGSGSSRE
Site 6S40SPGSSSGSGSSREDS
Site 7S42GSSSGSGSSREDSAP
Site 8S43SSSGSGSSREDSAPV
Site 9S47SGSSREDSAPVATAA
Site 10T73RHQQGKVTVKYDRKE
Site 11Y76QGKVTVKYDRKELRK
Site 12Y99VEQLGQLYGCEEEEM
Site 13S121DDLLDADSDEERASK
Site 14S127DSDEERASKLQEALV
Site 15Y137QEALVDCYKPTEEFI
Site 16S149EFIKELLSRIRGMRK
Site 17S158IRGMRKLSPPQKKSV
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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