KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ANGPTL6
Full Name:
Angiopoietin-related protein 6
Alias:
Angiopoietin-like protein 6;Angiopoietin-related growth factor;Angiopoietin-related protein 5
Type:
Mass (Da):
51694
Number AA:
470
UniProt ID:
Q8NI99
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T28
R
A
G
A
P
R
C
T
Y
T
F
V
L
P
P
Site 2
T30
G
A
P
R
C
T
Y
T
F
V
L
P
P
Q
K
Site 3
S49
V
C
W
S
G
P
A
S
T
R
A
T
P
E
A
Site 4
T53
G
P
A
S
T
R
A
T
P
E
A
A
N
A
S
Site 5
S100
V
R
A
L
R
K
E
S
R
G
L
S
A
R
L
Site 6
S104
R
K
E
S
R
G
L
S
A
R
L
G
Q
L
R
Site 7
S147
G
E
R
V
L
N
A
S
A
E
A
Q
R
A
A
Site 8
S176
Q
L
V
T
Q
Q
S
S
L
I
A
R
L
E
R
Site 9
S212
V
P
V
R
L
V
G
S
T
S
D
T
S
R
M
Site 10
T213
P
V
R
L
V
G
S
T
S
D
T
S
R
M
L
Site 11
S214
V
R
L
V
G
S
T
S
D
T
S
R
M
L
D
Site 12
T216
L
V
G
S
T
S
D
T
S
R
M
L
D
P
A
Site 13
S217
V
G
S
T
S
D
T
S
R
M
L
D
P
A
P
Site 14
T231
P
E
P
Q
R
D
Q
T
Q
R
Q
Q
E
P
M
Site 15
S240
R
Q
Q
E
P
M
A
S
P
M
P
A
G
H
P
Site 16
T251
A
G
H
P
A
V
P
T
K
P
V
G
P
W
Q
Site 17
S271
R
Q
A
G
H
E
Q
S
G
V
Y
E
L
R
V
Site 18
Y274
G
H
E
Q
S
G
V
Y
E
L
R
V
G
R
H
Site 19
Y316
F
F
T
T
W
Q
H
Y
K
A
G
F
G
R
P
Site 20
Y327
F
G
R
P
D
G
E
Y
W
L
G
L
E
P
V
Site 21
Y335
W
L
G
L
E
P
V
Y
Q
L
T
S
R
G
D
Site 22
T338
L
E
P
V
Y
Q
L
T
S
R
G
D
H
E
L
Site 23
Y361
G
R
G
A
R
A
H
Y
D
G
F
S
L
E
P
Site 24
S365
R
A
H
Y
D
G
F
S
L
E
P
E
S
D
H
Site 25
S370
G
F
S
L
E
P
E
S
D
H
Y
R
L
R
L
Site 26
Y373
L
E
P
E
S
D
H
Y
R
L
R
L
G
Q
Y
Site 27
Y380
Y
R
L
R
L
G
Q
Y
H
G
D
A
G
D
S
Site 28
S389
G
D
A
G
D
S
L
S
W
H
N
D
K
P
F
Site 29
S397
W
H
N
D
K
P
F
S
T
V
D
R
D
R
D
Site 30
T398
H
N
D
K
P
F
S
T
V
D
R
D
R
D
S
Site 31
S405
T
V
D
R
D
R
D
S
Y
S
G
N
C
A
L
Site 32
Y406
V
D
R
D
R
D
S
Y
S
G
N
C
A
L
Y
Site 33
S407
D
R
D
R
D
S
Y
S
G
N
C
A
L
Y
Q
Site 34
Y438
V
W
H
H
G
G
H
Y
R
S
R
Y
Q
D
G
Site 35
Y442
G
G
H
Y
R
S
R
Y
Q
D
G
V
Y
W
A
Site 36
Y447
S
R
Y
Q
D
G
V
Y
W
A
E
F
R
G
G
Site 37
S457
E
F
R
G
G
A
Y
S
L
R
K
A
A
M
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation