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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZFP28
Full Name:
Zinc finger protein 28 homolog
Alias:
Krueppel-like zinc finger factor X6
Type:
Mass (Da):
98705
Number AA:
868
UniProt ID:
Q8NHY6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
R
G
A
A
S
A
S
V
R
E
P
T
P
L
Site 2
T13
S
A
S
V
R
E
P
T
P
L
P
G
R
G
A
Site 3
T23
P
G
R
G
A
P
R
T
K
P
R
A
G
R
G
Site 4
T32
P
R
A
G
R
G
P
T
V
G
T
P
A
T
L
Site 5
S49
P
A
R
G
R
P
R
S
R
N
G
L
A
S
K
Site 6
S55
R
S
R
N
G
L
A
S
K
G
Q
R
G
A
A
Site 7
T64
G
Q
R
G
A
A
P
T
G
P
G
H
R
A
L
Site 8
S73
P
G
H
R
A
L
P
S
R
D
T
A
L
P
Q
Site 9
T76
R
A
L
P
S
R
D
T
A
L
P
Q
E
R
N
Site 10
T91
K
K
L
E
A
V
G
T
G
I
E
P
K
A
M
Site 11
S113
G
D
V
A
V
D
F
S
Q
E
E
W
E
W
L
Site 12
Y128
N
P
I
Q
R
N
L
Y
R
K
V
M
L
E
N
Site 13
Y136
R
K
V
M
L
E
N
Y
R
N
L
A
S
L
G
Site 14
S141
E
N
Y
R
N
L
A
S
L
G
L
C
V
S
K
Site 15
S154
S
K
P
D
V
I
S
S
L
E
Q
G
K
E
P
Site 16
T163
E
Q
G
K
E
P
W
T
V
K
R
K
M
T
R
Site 17
S197
D
F
C
E
G
K
L
S
Q
A
V
I
T
E
R
Site 18
T202
K
L
S
Q
A
V
I
T
E
R
L
T
S
Y
N
Site 19
T206
A
V
I
T
E
R
L
T
S
Y
N
L
E
Y
S
Site 20
S207
V
I
T
E
R
L
T
S
Y
N
L
E
Y
S
L
Site 21
Y212
L
T
S
Y
N
L
E
Y
S
L
L
G
E
H
W
Site 22
S213
T
S
Y
N
L
E
Y
S
L
L
G
E
H
W
D
Site 23
Y221
L
L
G
E
H
W
D
Y
D
A
L
F
E
T
Q
Site 24
S262
N
G
I
W
E
N
N
S
D
L
G
S
A
G
H
Site 25
S266
E
N
N
S
D
L
G
S
A
G
H
C
V
A
K
Site 26
S278
V
A
K
P
D
L
V
S
L
L
E
Q
E
K
E
Site 27
T294
W
M
V
K
R
E
L
T
G
S
L
F
S
G
Q
Site 28
S296
V
K
R
E
L
T
G
S
L
F
S
G
Q
R
S
Site 29
S299
E
L
T
G
S
L
F
S
G
Q
R
S
V
H
E
Site 30
S303
S
L
F
S
G
Q
R
S
V
H
E
T
Q
E
L
Site 31
T307
G
Q
R
S
V
H
E
T
Q
E
L
F
P
K
Q
Site 32
Y317
L
F
P
K
Q
D
S
Y
A
E
G
V
T
D
R
Site 33
T322
D
S
Y
A
E
G
V
T
D
R
T
S
N
T
K
Site 34
T325
A
E
G
V
T
D
R
T
S
N
T
K
L
D
C
Site 35
S326
E
G
V
T
D
R
T
S
N
T
K
L
D
C
S
Site 36
T328
V
T
D
R
T
S
N
T
K
L
D
C
S
S
F
Site 37
S333
S
N
T
K
L
D
C
S
S
F
R
E
N
W
D
Site 38
S334
N
T
K
L
D
C
S
S
F
R
E
N
W
D
S
Site 39
S341
S
F
R
E
N
W
D
S
D
Y
V
F
G
R
K
Site 40
Y343
R
E
N
W
D
S
D
Y
V
F
G
R
K
L
A
Site 41
T363
Q
F
R
Q
E
P
I
T
H
N
K
T
L
S
K
Site 42
T367
E
P
I
T
H
N
K
T
L
S
K
E
R
E
R
Site 43
S369
I
T
H
N
K
T
L
S
K
E
R
E
R
T
Y
Site 44
T375
L
S
K
E
R
E
R
T
Y
N
K
S
G
R
W
Site 45
Y376
S
K
E
R
E
R
T
Y
N
K
S
G
R
W
F
Site 46
Y384
N
K
S
G
R
W
F
Y
L
D
D
S
E
E
K
Site 47
S397
E
K
V
H
N
R
D
S
I
K
N
F
Q
K
S
Site 48
S404
S
I
K
N
F
Q
K
S
S
V
V
I
K
Q
T
Site 49
S405
I
K
N
F
Q
K
S
S
V
V
I
K
Q
T
G
Site 50
T428
K
C
N
E
C
K
K
T
F
T
Q
S
S
S
L
Site 51
T430
N
E
C
K
K
T
F
T
Q
S
S
S
L
T
V
Site 52
S432
C
K
K
T
F
T
Q
S
S
S
L
T
V
H
Q
Site 53
S434
K
T
F
T
Q
S
S
S
L
T
V
H
Q
R
I
Site 54
T436
F
T
Q
S
S
S
L
T
V
H
Q
R
I
H
T
Site 55
T443
T
V
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 56
Y448
I
H
T
G
E
K
P
Y
K
C
N
E
C
G
K
Site 57
S458
N
E
C
G
K
A
F
S
D
G
S
S
F
A
R
Site 58
S462
K
A
F
S
D
G
S
S
F
A
R
H
Q
R
C
Site 59
T471
A
R
H
Q
R
C
H
T
G
K
K
P
Y
E
C
Site 60
Y476
C
H
T
G
K
K
P
Y
E
C
I
E
C
G
K
Site 61
Y497
S
L
I
R
H
W
R
Y
Y
H
T
G
E
K
P
Site 62
Y498
L
I
R
H
W
R
Y
Y
H
T
G
E
K
P
F
Site 63
T528
N
Q
H
R
R
I
H
T
G
E
K
P
Y
K
C
Site 64
Y533
I
H
T
G
E
K
P
Y
K
C
D
V
C
H
K
Site 65
S546
H
K
S
F
R
Y
G
S
S
L
T
V
H
Q
R
Site 66
S547
K
S
F
R
Y
G
S
S
L
T
V
H
Q
R
I
Site 67
T549
F
R
Y
G
S
S
L
T
V
H
Q
R
I
H
T
Site 68
T556
T
V
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 69
Y561
I
H
T
G
E
K
P
Y
E
C
D
V
C
R
K
Site 70
S571
D
V
C
R
K
A
F
S
H
H
A
S
L
T
Q
Site 71
S575
K
A
F
S
H
H
A
S
L
T
Q
H
Q
R
V
Site 72
T577
F
S
H
H
A
S
L
T
Q
H
Q
R
V
H
S
Site 73
S584
T
Q
H
Q
R
V
H
S
G
E
K
P
F
K
C
Site 74
S606
R
Q
N
I
H
L
A
S
H
L
R
I
H
T
G
Site 75
T612
A
S
H
L
R
I
H
T
G
E
K
P
F
E
C
Site 76
S625
E
C
A
E
C
G
K
S
F
S
I
S
S
Q
L
Site 77
S627
A
E
C
G
K
S
F
S
I
S
S
Q
L
A
T
Site 78
S629
C
G
K
S
F
S
I
S
S
Q
L
A
T
H
Q
Site 79
S630
G
K
S
F
S
I
S
S
Q
L
A
T
H
Q
R
Site 80
T634
S
I
S
S
Q
L
A
T
H
Q
R
I
H
T
G
Site 81
T640
A
T
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 82
Y645
I
H
T
G
E
K
P
Y
E
C
K
V
C
S
K
Site 83
T655
K
V
C
S
K
A
F
T
Q
K
A
H
L
A
Q
Site 84
Y673
T
H
T
G
E
K
P
Y
E
C
K
E
C
G
K
Site 85
S683
K
E
C
G
K
A
F
S
Q
T
T
H
L
I
Q
Site 86
T686
G
K
A
F
S
Q
T
T
H
L
I
Q
H
Q
R
Site 87
T696
I
Q
H
Q
R
V
H
T
G
E
K
P
Y
K
C
Site 88
Y701
V
H
T
G
E
K
P
Y
K
C
M
E
C
G
K
Site 89
S714
G
K
A
F
G
D
N
S
S
C
T
Q
H
Q
R
Site 90
S715
K
A
F
G
D
N
S
S
C
T
Q
H
Q
R
L
Site 91
T724
T
Q
H
Q
R
L
H
T
G
Q
R
P
Y
E
C
Site 92
Y729
L
H
T
G
Q
R
P
Y
E
C
I
E
C
G
K
Site 93
T740
E
C
G
K
A
F
K
T
K
S
S
L
I
C
H
Site 94
S742
G
K
A
F
K
T
K
S
S
L
I
C
H
R
R
Site 95
S750
S
L
I
C
H
R
R
S
H
T
G
E
K
P
Y
Site 96
T752
I
C
H
R
R
S
H
T
G
E
K
P
Y
E
C
Site 97
Y757
S
H
T
G
E
K
P
Y
E
C
S
V
C
G
K
Site 98
S760
G
E
K
P
Y
E
C
S
V
C
G
K
A
F
S
Site 99
S767
S
V
C
G
K
A
F
S
H
R
Q
S
L
S
V
Site 100
S771
K
A
F
S
H
R
Q
S
L
S
V
H
Q
R
I
Site 101
S773
F
S
H
R
Q
S
L
S
V
H
Q
R
I
H
S
Site 102
S780
S
V
H
Q
R
I
H
S
G
K
K
P
Y
E
C
Site 103
Y785
I
H
S
G
K
K
P
Y
E
C
K
E
C
R
K
Site 104
T808
N
Q
H
K
R
V
H
T
G
E
R
S
Y
N
Y
Site 105
Y813
V
H
T
G
E
R
S
Y
N
Y
K
K
S
R
K
Site 106
Y815
T
G
E
R
S
Y
N
Y
K
K
S
R
K
V
F
Site 107
S818
R
S
Y
N
Y
K
K
S
R
K
V
F
R
Q
T
Site 108
T825
S
R
K
V
F
R
Q
T
A
H
L
A
H
H
Q
Site 109
T836
A
H
H
Q
R
I
H
T
G
E
S
S
T
C
P
Site 110
S840
R
I
H
T
G
E
S
S
T
C
P
S
L
P
S
Site 111
T841
I
H
T
G
E
S
S
T
C
P
S
L
P
S
T
Site 112
S844
G
E
S
S
T
C
P
S
L
P
S
T
S
N
P
Site 113
S847
S
T
C
P
S
L
P
S
T
S
N
P
V
D
L
Site 114
T848
T
C
P
S
L
P
S
T
S
N
P
V
D
L
F
Site 115
S849
C
P
S
L
P
S
T
S
N
P
V
D
L
F
P
Site 116
S863
P
K
F
L
W
N
P
S
S
L
P
S
P
_
_
Site 117
S864
K
F
L
W
N
P
S
S
L
P
S
P
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation