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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TDRD7
Full Name:
Tudor domain-containing protein 7
Alias:
PCTAIRE2-binding protein; PCTAIRE2BP; Trap; Tudor domain containing 7; Tudor domain-containing 7; Tudor repeat associator with PCTAIRE 2
Type:
Adaptor/scaffold
Mass (Da):
123586
Number AA:
1098
UniProt ID:
Q8NHU6
International Prot ID:
IPI00478741
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0033391
Uniprot
OncoNet
Molecular Function:
GO:0003676
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
L
E
G
D
L
V
S
K
M
L
R
A
V
L
Site 2
Y31
L
P
R
L
Q
G
E
Y
R
S
L
T
G
D
W
Site 3
S33
R
L
Q
G
E
Y
R
S
L
T
G
D
W
I
P
Site 4
T35
Q
G
E
Y
R
S
L
T
G
D
W
I
P
F
K
Site 5
T64
P
A
V
V
R
I
E
T
S
R
S
G
E
I
T
Site 6
S67
V
R
I
E
T
S
R
S
G
E
I
T
C
Y
A
Site 7
T71
T
S
R
S
G
E
I
T
C
Y
A
M
A
C
T
Site 8
Y73
R
S
G
E
I
T
C
Y
A
M
A
C
T
E
T
Site 9
S92
Q
L
V
A
R
Q
R
S
S
K
R
K
T
G
R
Site 10
S93
L
V
A
R
Q
R
S
S
K
R
K
T
G
R
Q
Site 11
T97
Q
R
S
S
K
R
K
T
G
R
Q
V
N
C
Q
Site 12
T110
C
Q
M
R
V
K
K
T
M
P
F
F
L
E
G
Site 13
S133
P
G
F
A
S
N
F
S
V
G
K
K
P
N
P
Site 14
S149
P
L
R
D
K
G
N
S
V
G
V
K
P
D
A
Site 15
S159
V
K
P
D
A
E
M
S
P
Y
M
L
H
T
T
Site 16
Y161
P
D
A
E
M
S
P
Y
M
L
H
T
T
L
G
Site 17
T166
S
P
Y
M
L
H
T
T
L
G
N
E
A
F
K
Site 18
T182
I
P
V
Q
R
H
V
T
M
S
T
N
N
R
F
Site 19
S184
V
Q
R
H
V
T
M
S
T
N
N
R
F
S
P
Site 20
T185
Q
R
H
V
T
M
S
T
N
N
R
F
S
P
K
Site 21
S190
M
S
T
N
N
R
F
S
P
K
A
S
L
Q
P
Site 22
S194
N
R
F
S
P
K
A
S
L
Q
P
P
L
Q
M
Site 23
S204
P
P
L
Q
M
H
L
S
R
T
S
T
K
E
M
Site 24
S207
Q
M
H
L
S
R
T
S
T
K
E
M
S
D
N
Site 25
T208
M
H
L
S
R
T
S
T
K
E
M
S
D
N
L
Site 26
S212
R
T
S
T
K
E
M
S
D
N
L
N
Q
T
V
Site 27
T218
M
S
D
N
L
N
Q
T
V
E
K
P
N
V
K
Site 28
S229
P
N
V
K
P
P
A
S
Y
T
Y
K
M
D
E
Site 29
Y265
P
H
F
Y
K
E
L
Y
K
E
D
L
N
Q
G
Site 30
Y299
G
G
Q
D
L
L
L
Y
P
A
K
R
K
Q
L
Site 31
S309
K
R
K
Q
L
L
R
S
E
L
D
T
E
K
V
Site 32
T313
L
L
R
S
E
L
D
T
E
K
V
P
L
S
P
Site 33
S319
D
T
E
K
V
P
L
S
P
L
P
G
P
K
Q
Site 34
T327
P
L
P
G
P
K
Q
T
P
P
L
K
G
C
P
Site 35
T335
P
P
L
K
G
C
P
T
V
M
A
G
D
F
K
Site 36
S359
Y
T
S
G
L
W
A
S
A
L
P
K
A
F
E
Site 37
Y369
P
K
A
F
E
E
M
Y
K
V
K
F
P
E
D
Site 38
Y392
S
D
V
C
S
I
D
Y
I
S
G
N
P
Q
K
Site 39
Y434
K
A
M
V
E
Q
E
Y
L
Q
V
E
E
S
I
Site 40
S440
E
Y
L
Q
V
E
E
S
I
A
E
S
A
N
T
Site 41
S444
V
E
E
S
I
A
E
S
A
N
T
F
M
E
D
Site 42
S466
I
P
T
E
A
S
P
S
V
L
V
V
E
L
S
Site 43
Y482
T
N
E
V
V
I
R
Y
V
G
K
D
Y
S
A
Site 44
Y487
I
R
Y
V
G
K
D
Y
S
A
A
Q
E
L
M
Site 45
S488
R
Y
V
G
K
D
Y
S
A
A
Q
E
L
M
E
Site 46
Y501
M
E
D
E
M
K
E
Y
Y
S
K
N
P
K
I
Site 47
Y502
E
D
E
M
K
E
Y
Y
S
K
N
P
K
I
T
Site 48
T509
Y
S
K
N
P
K
I
T
P
V
Q
A
V
N
V
Site 49
S536
W
L
R
A
Q
V
I
S
T
E
E
N
K
I
K
Site 50
Y546
E
N
K
I
K
V
C
Y
V
D
Y
G
F
S
E
Site 51
Y549
I
K
V
C
Y
V
D
Y
G
F
S
E
N
V
E
Site 52
S558
F
S
E
N
V
E
K
S
K
A
Y
K
L
N
P
Site 53
Y561
N
V
E
K
S
K
A
Y
K
L
N
P
K
F
C
Site 54
S569
K
L
N
P
K
F
C
S
L
S
F
Q
A
T
K
Site 55
S571
N
P
K
F
C
S
L
S
F
Q
A
T
K
C
K
Site 56
Y620
D
I
P
L
V
V
L
Y
D
T
S
G
E
D
D
Site 57
Y653
H
L
Q
V
D
A
M
Y
T
N
V
K
V
T
N
Site 58
S680
C
K
G
L
N
K
L
S
D
L
L
R
K
I
E
Site 59
Y689
L
L
R
K
I
E
D
Y
F
H
C
K
H
M
T
Site 60
T724
K
W
L
R
V
E
I
T
N
V
H
S
S
R
A
Site 61
S744
L
D
S
G
T
V
T
S
V
K
V
S
E
L
R
Site 62
S748
T
V
T
S
V
K
V
S
E
L
R
E
I
P
P
Site 63
T806
S
D
C
S
I
K
V
T
K
V
D
E
T
R
G
Site 64
Y818
T
R
G
I
A
H
V
Y
L
F
T
P
K
N
F
Site 65
T821
I
A
H
V
Y
L
F
T
P
K
N
F
P
D
P
Site 66
S831
N
F
P
D
P
H
R
S
I
N
R
Q
I
T
N
Site 67
T837
R
S
I
N
R
Q
I
T
N
A
D
L
W
K
H
Site 68
S851
H
Q
K
D
V
F
L
S
A
I
S
S
G
A
D
Site 69
S859
A
I
S
S
G
A
D
S
P
N
S
K
N
G
N
Site 70
S862
S
G
A
D
S
P
N
S
K
N
G
N
M
P
M
Site 71
T882
E
N
F
R
K
N
L
T
D
V
I
K
K
S
M
Site 72
S888
L
T
D
V
I
K
K
S
M
V
D
H
T
S
A
Site 73
T893
K
K
S
M
V
D
H
T
S
A
F
S
T
E
E
Site 74
S894
K
S
M
V
D
H
T
S
A
F
S
T
E
E
L
Site 75
T898
D
H
T
S
A
F
S
T
E
E
L
P
P
P
V
Site 76
S908
L
P
P
P
V
H
L
S
K
P
G
E
H
M
D
Site 77
Y917
P
G
E
H
M
D
V
Y
V
P
V
A
C
H
P
Site 78
Y948
L
M
E
E
M
I
L
Y
Y
S
V
S
E
E
R
Site 79
S950
E
E
M
I
L
Y
Y
S
V
S
E
E
R
H
I
Site 80
Y965
A
V
E
K
D
Q
V
Y
A
A
K
V
E
N
K
Site 81
Y990
T
N
G
L
V
S
V
Y
E
L
D
Y
G
K
H
Site 82
Y994
V
S
V
Y
E
L
D
Y
G
K
H
E
L
V
N
Site 83
T1079
V
D
T
S
L
P
D
T
D
T
W
I
H
D
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation