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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MYRIP
Full Name:
Rab effector MyRIP
Alias:
FLJ44025; Myosin VIIA and Rab interacting protein; SLAC2C; SLAC2-C
Type:
Mass (Da):
95706
Number AA:
859
UniProt ID:
Q8NFW9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006886
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
G
R
K
L
D
L
S
G
L
T
D
D
E
T
Site 2
T15
S
G
L
T
D
D
E
T
E
H
V
L
Q
V
V
Site 3
S37
K
K
E
E
E
R
L
S
E
L
K
Q
K
L
D
Site 4
S48
Q
K
L
D
E
E
G
S
K
C
S
I
L
S
K
Site 5
S51
D
E
E
G
S
K
C
S
I
L
S
K
H
Q
Q
Site 6
S54
G
S
K
C
S
I
L
S
K
H
Q
Q
F
V
E
Site 7
T77
P
F
T
F
L
V
N
T
K
R
Q
C
G
D
C
Site 8
S117
A
R
L
L
R
A
Q
S
L
E
W
F
Y
N
N
Site 9
Y122
A
Q
S
L
E
W
F
Y
N
N
V
K
S
R
F
Site 10
S134
S
R
F
K
R
F
G
S
A
K
V
L
K
N
L
Site 11
Y142
A
K
V
L
K
N
L
Y
R
K
H
R
L
E
S
Site 12
S149
Y
R
K
H
R
L
E
S
G
A
C
F
D
I
L
Site 13
S163
L
G
G
S
L
F
E
S
N
L
E
N
E
G
S
Site 14
S170
S
N
L
E
N
E
G
S
I
S
G
S
D
S
T
Site 15
S172
L
E
N
E
G
S
I
S
G
S
D
S
T
F
Y
Site 16
S174
N
E
G
S
I
S
G
S
D
S
T
F
Y
R
Q
Site 17
S176
G
S
I
S
G
S
D
S
T
F
Y
R
Q
S
E
Site 18
T177
S
I
S
G
S
D
S
T
F
Y
R
Q
S
E
G
Site 19
Y179
S
G
S
D
S
T
F
Y
R
Q
S
E
G
H
S
Site 20
S182
D
S
T
F
Y
R
Q
S
E
G
H
S
V
M
D
Site 21
S186
Y
R
Q
S
E
G
H
S
V
M
D
T
L
A
V
Site 22
S207
E
A
I
E
E
A
I
S
K
A
E
A
Y
G
D
Site 23
S215
K
A
E
A
Y
G
D
S
L
D
K
Q
N
E
A
Site 24
Y224
D
K
Q
N
E
A
S
Y
L
R
D
H
K
E
E
Site 25
S250
K
I
I
R
K
Q
K
S
K
S
E
Q
Q
V
E
Site 26
S252
I
R
K
Q
K
S
K
S
E
Q
Q
V
E
E
E
Site 27
S267
P
G
W
P
H
P
Q
S
C
S
T
K
V
A
D
Site 28
S278
K
V
A
D
E
G
T
S
A
S
P
G
G
Y
R
Site 29
S280
A
D
E
G
T
S
A
S
P
G
G
Y
R
A
P
Site 30
Y284
T
S
A
S
P
G
G
Y
R
A
P
A
A
L
W
Site 31
S295
A
A
L
W
R
S
Q
S
A
F
S
I
T
G
E
Site 32
T307
T
G
E
E
A
L
K
T
P
P
V
E
A
P
S
Site 33
S314
T
P
P
V
E
A
P
S
R
Q
P
R
D
Q
G
Site 34
S328
G
Q
H
P
R
A
E
S
A
L
P
S
W
K
S
Site 35
S332
R
A
E
S
A
L
P
S
W
K
S
V
D
R
L
Site 36
S335
S
A
L
P
S
W
K
S
V
D
R
L
D
E
T
Site 37
T342
S
V
D
R
L
D
E
T
N
L
A
P
V
L
Q
Site 38
S350
N
L
A
P
V
L
Q
S
P
D
G
N
W
V
A
Site 39
S374
R
L
L
A
K
P
K
S
G
T
F
Q
A
L
E
Site 40
S385
Q
A
L
E
V
A
S
S
V
A
S
A
Y
D
E
Site 41
S388
E
V
A
S
S
V
A
S
A
Y
D
E
M
G
S
Site 42
Y390
A
S
S
V
A
S
A
Y
D
E
M
G
S
D
S
Site 43
S395
S
A
Y
D
E
M
G
S
D
S
E
E
D
F
D
Site 44
S397
Y
D
E
M
G
S
D
S
E
E
D
F
D
W
S
Site 45
S404
S
E
E
D
F
D
W
S
E
A
L
S
K
L
C
Site 46
S408
F
D
W
S
E
A
L
S
K
L
C
P
R
S
R
Site 47
S414
L
S
K
L
C
P
R
S
R
A
L
P
R
N
P
Site 48
T426
R
N
P
Q
P
Q
P
T
Q
A
Q
S
S
D
Q
Site 49
S439
D
Q
G
P
I
A
A
S
P
S
S
A
L
S
P
Site 50
S441
G
P
I
A
A
S
P
S
S
A
L
S
P
N
P
Site 51
S442
P
I
A
A
S
P
S
S
A
L
S
P
N
P
E
Site 52
S445
A
S
P
S
S
A
L
S
P
N
P
E
A
M
C
Site 53
S453
P
N
P
E
A
M
C
S
D
S
E
T
S
S
A
Site 54
S455
P
E
A
M
C
S
D
S
E
T
S
S
A
G
S
Site 55
T457
A
M
C
S
D
S
E
T
S
S
A
G
S
S
R
Site 56
S458
M
C
S
D
S
E
T
S
S
A
G
S
S
R
E
Site 57
S459
C
S
D
S
E
T
S
S
A
G
S
S
R
E
V
Site 58
S462
S
E
T
S
S
A
G
S
S
R
E
V
G
H
Q
Site 59
S463
E
T
S
S
A
G
S
S
R
E
V
G
H
Q
A
Site 60
S473
V
G
H
Q
A
R
L
S
W
L
Q
R
K
A
P
Site 61
S504
N
F
N
P
Q
L
A
S
R
E
T
S
D
S
S
Site 62
T507
P
Q
L
A
S
R
E
T
S
D
S
S
E
P
E
Site 63
S508
Q
L
A
S
R
E
T
S
D
S
S
E
P
E
E
Site 64
S510
A
S
R
E
T
S
D
S
S
E
P
E
E
A
P
Site 65
S511
S
R
E
T
S
D
S
S
E
P
E
E
A
P
H
Site 66
T519
E
P
E
E
A
P
H
T
T
D
R
R
A
R
R
Site 67
T520
P
E
E
A
P
H
T
T
D
R
R
A
R
R
W
Site 68
S534
W
R
R
A
R
L
G
S
E
E
P
S
K
E
P
Site 69
S538
R
L
G
S
E
E
P
S
K
E
P
S
S
P
S
Site 70
S542
E
E
P
S
K
E
P
S
S
P
S
A
Q
L
R
Site 71
S543
E
P
S
K
E
P
S
S
P
S
A
Q
L
R
D
Site 72
T553
A
Q
L
R
D
L
D
T
H
Q
V
S
D
D
L
Site 73
S557
D
L
D
T
H
Q
V
S
D
D
L
S
E
T
D
Site 74
S561
H
Q
V
S
D
D
L
S
E
T
D
I
S
N
E
Site 75
S566
D
L
S
E
T
D
I
S
N
E
A
R
D
P
Q
Site 76
T574
N
E
A
R
D
P
Q
T
L
T
D
T
T
E
E
Site 77
T579
P
Q
T
L
T
D
T
T
E
E
K
R
R
N
R
Site 78
Y588
E
K
R
R
N
R
L
Y
E
L
A
M
K
M
S
Site 79
S595
Y
E
L
A
M
K
M
S
E
K
E
T
S
S
G
Site 80
S600
K
M
S
E
K
E
T
S
S
G
E
D
Q
E
S
Site 81
S607
S
S
G
E
D
Q
E
S
E
P
K
T
E
S
E
Site 82
T611
D
Q
E
S
E
P
K
T
E
S
E
N
Q
K
E
Site 83
S613
E
S
E
P
K
T
E
S
E
N
Q
K
E
S
L
Site 84
S619
E
S
E
N
Q
K
E
S
L
S
S
E
D
N
S
Site 85
S621
E
N
Q
K
E
S
L
S
S
E
D
N
S
Q
S
Site 86
S622
N
Q
K
E
S
L
S
S
E
D
N
S
Q
S
V
Site 87
S626
S
L
S
S
E
D
N
S
Q
S
V
Q
E
E
L
Site 88
S628
S
S
E
D
N
S
Q
S
V
Q
E
E
L
K
K
Site 89
S638
E
E
L
K
K
K
F
S
A
V
S
L
C
N
I
Site 90
S641
K
K
K
F
S
A
V
S
L
C
N
I
S
T
E
Site 91
S663
T
E
E
L
I
A
G
S
T
G
P
W
E
S
P
Site 92
S669
G
S
T
G
P
W
E
S
P
Q
V
P
P
D
R
Site 93
T685
K
G
M
F
P
R
G
T
D
Q
V
R
L
D
E
Site 94
S696
R
L
D
E
Q
L
T
S
L
E
E
N
V
Y
L
Site 95
T716
Y
G
L
E
T
Q
L
T
E
L
E
D
A
A
R
Site 96
S727
D
A
A
R
C
I
H
S
G
T
D
E
T
H
L
Site 97
S756
H
H
A
E
L
Q
I
S
D
I
E
S
R
I
S
Site 98
T779
I
A
P
C
V
R
F
T
R
R
R
D
Q
K
Q
Site 99
T792
K
Q
R
T
Q
V
Q
T
I
D
T
S
R
Q
Q
Site 100
T795
T
Q
V
Q
T
I
D
T
S
R
Q
Q
R
R
K
Site 101
T815
V
K
A
E
K
I
E
T
S
S
V
T
T
I
K
Site 102
S817
A
E
K
I
E
T
S
S
V
T
T
I
K
T
F
Site 103
T820
I
E
T
S
S
V
T
T
I
K
T
F
N
H
N
Site 104
T835
F
I
L
Q
G
S
S
T
N
R
T
K
E
R
K
Site 105
T838
Q
G
S
S
T
N
R
T
K
E
R
K
G
T
T
Site 106
T844
R
T
K
E
R
K
G
T
T
K
D
L
M
E
P
Site 107
T845
T
K
E
R
K
G
T
T
K
D
L
M
E
P
A
Site 108
Y859
A
L
E
S
A
V
M
Y
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation