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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TOR1AIP2
Full Name:
Torsin-1A-interacting protein 2
Alias:
LULL1; Lumenal domain like LAP1; Lumenal domain-like LAP1; TOIP2; Torsin A interacting protein 2
Type:
Endoplasmic reticulum
Mass (Da):
51263
Number AA:
470
UniProt ID:
Q8NFQ8
International Prot ID:
IPI00168878
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0016021
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
L
R
E
P
Q
E
D
S
Q
K
D
L
E
N
D
Site 2
S22
K
D
L
E
N
D
P
S
V
N
S
Q
A
Q
E
Site 3
S25
E
N
D
P
S
V
N
S
Q
A
Q
E
T
T
I
Site 4
S45
E
E
A
E
I
L
H
S
A
C
G
L
S
K
D
Site 5
T58
K
D
H
Q
E
V
E
T
E
G
P
E
S
A
D
Site 6
S63
V
E
T
E
G
P
E
S
A
D
T
G
D
K
S
Site 7
T66
E
G
P
E
S
A
D
T
G
D
K
S
E
S
P
Site 8
S70
S
A
D
T
G
D
K
S
E
S
P
D
E
A
N
Site 9
S72
D
T
G
D
K
S
E
S
P
D
E
A
N
V
G
Site 10
T86
G
K
H
P
K
D
K
T
E
D
E
N
K
Q
S
Site 11
S93
T
E
D
E
N
K
Q
S
F
L
D
G
G
K
G
Site 12
S105
G
K
G
H
H
L
P
S
E
N
L
G
K
E
P
Site 13
S118
E
P
L
D
P
D
P
S
H
S
P
S
D
K
V
Site 14
S120
L
D
P
D
P
S
H
S
P
S
D
K
V
G
R
Site 15
S122
P
D
P
S
H
S
P
S
D
K
V
G
R
A
D
Site 16
S134
R
A
D
A
H
L
G
S
S
S
V
A
L
P
K
Site 17
S136
D
A
H
L
G
S
S
S
V
A
L
P
K
E
A
Site 18
S144
V
A
L
P
K
E
A
S
D
G
T
G
A
S
Q
Site 19
S150
A
S
D
G
T
G
A
S
Q
E
P
P
T
T
D
Site 20
T155
G
A
S
Q
E
P
P
T
T
D
S
Q
E
A
Q
Site 21
T156
A
S
Q
E
P
P
T
T
D
S
Q
E
A
Q
S
Site 22
S158
Q
E
P
P
T
T
D
S
Q
E
A
Q
S
P
G
Site 23
S163
T
D
S
Q
E
A
Q
S
P
G
H
S
S
A
G
Site 24
S167
E
A
Q
S
P
G
H
S
S
A
G
Q
E
G
E
Site 25
T176
A
G
Q
E
G
E
D
T
L
R
R
R
L
L
A
Site 26
T206
I
K
E
N
A
Q
D
T
M
R
Q
I
N
K
K
Site 27
S237
V
V
A
S
S
V
N
S
Y
Y
S
S
P
A
Q
Site 28
Y238
V
A
S
S
V
N
S
Y
Y
S
S
P
A
Q
Q
Site 29
Y239
A
S
S
V
N
S
Y
Y
S
S
P
A
Q
Q
V
Site 30
S240
S
S
V
N
S
Y
Y
S
S
P
A
Q
Q
V
P
Site 31
S241
S
V
N
S
Y
Y
S
S
P
A
Q
Q
V
P
K
Site 32
S271
D
K
F
P
G
Q
S
S
F
L
W
Q
R
G
R
Site 33
T295
S
N
P
T
E
P
A
T
I
I
F
T
A
A
R
Site 34
T307
A
A
R
E
G
R
E
T
L
K
C
L
S
H
H
Site 35
Y319
S
H
H
V
A
D
A
Y
T
S
S
Q
K
V
S
Site 36
S322
V
A
D
A
Y
T
S
S
Q
K
V
S
P
I
Q
Site 37
S326
Y
T
S
S
Q
K
V
S
P
I
Q
I
D
G
A
Site 38
S340
A
G
R
T
W
Q
D
S
D
T
V
K
L
L
V
Site 39
T342
R
T
W
Q
D
S
D
T
V
K
L
L
V
D
L
Site 40
Y379
A
G
S
T
L
I
F
Y
K
Y
C
D
H
E
N
Site 41
Y381
S
T
L
I
F
Y
K
Y
C
D
H
E
N
A
A
Site 42
S408
E
E
E
T
L
E
A
S
V
G
P
R
E
T
E
Site 43
T414
A
S
V
G
P
R
E
T
E
E
K
V
R
D
L
Site 44
T427
D
L
L
W
A
K
F
T
N
S
D
T
P
T
S
Site 45
S429
L
W
A
K
F
T
N
S
D
T
P
T
S
F
N
Site 46
T431
A
K
F
T
N
S
D
T
P
T
S
F
N
H
M
Site 47
T433
F
T
N
S
D
T
P
T
S
F
N
H
M
D
S
Site 48
S434
T
N
S
D
T
P
T
S
F
N
H
M
D
S
D
Site 49
S440
T
S
F
N
H
M
D
S
D
K
L
S
G
L
W
Site 50
S444
H
M
D
S
D
K
L
S
G
L
W
S
R
I
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation