PhosphoNET

           
Protein Info 
   
Short Name:  NBEA
Full Name:  Neurobeachin
Alias:  BCL8B; FLJ10197; KIAA1544; Lysosomal trafficking regulator 2
Type:  Vesicle protein
Mass (Da):  327864
Number AA:  2946
UniProt ID:  Q8NFP9
International Prot ID:  IPI00328195
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829  GO:0012505  GO:0019898 Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S32AGGGGGGSGGGGTGG
Site 2S40GGGGTGGSGMGELRG
Site 3S64PAGMINPSVPIRNIR
Site 4S147FTAILRKSVRNLQTS
Site 5S154SVRNLQTSTEVGLIE
Site 6S168EQVLLKMSAVDDMIA
Site 7S200KELKLLFSMLRGESG
Site 8S206FSMLRGESGIWPRHA
Site 9S218RHAVKLLSVLNQMPQ
Site 10T231PQRHGPDTFFNFPGC
Site 11Y253 PPIAKWPYQNGFTLN
Site 12Y279NVDKDKPYLYCFRTS
Site 13Y281DKDKPYLYCFRTSKG
Site 14T285PYLYCFRTSKGVGYS
Site 15Y291RTSKGVGYSAHFVGN
Site 16S304GNCLIVTSLKSKGKG
Site 17S307LIVTSLKSKGKGFQH
Site 18Y334MISIVHIYNRWRNSE
Site 19Y345RNSEIRCYVNGQLVS
Site 20Y366HVNTNDSYDKCFLGS
Site 21Y412IHQLGPGYKSTFKFK
Site 22S414QLGPGYKSTFKFKSE
Site 23T415LGPGYKSTFKFKSES
Site 24S420KSTFKFKSESDIHLA
Site 25S422TFKFKSESDIHLAEH
Site 26Y435EHHKQVLYDGKLASS
Site 27S442YDGKLASSIAFTYNA
Site 28S461AQLCLESSPKENASI
Site 29S467SSPKENASIFVHSPH
Site 30S491IVTHSIHSAIHSIGG
Site 31S517DNRQLNDSQVETTVC
Site 32S561IGYLLEKSSRVHITR
Site 33S562GYLLEKSSRVHITRA
Site 34Y580QFLSFAKYLDGLSHG
Site 35S585AKYLDGLSHGAPLLK
Site 36T608NPAIWIHTPAKVQLS
Site 37S615TPAKVQLSLYTYLSA
Site 38Y619VQLSLYTYLSAEFIG
Site 39T663PADSSGITPKGLDGP
Site 40S673GLDGPRPSQKEIISL
Site 41Y709ELQSILNYLLTMHED
Site 42T712SILNYLLTMHEDENI
Site 43S736LMSEHPASMIPAFDQ
Site 44Y751RNGIRVIYKLLASKS
Site 45S758YKLLASKSESIWVQA
Site 46S760LLASKSESIWVQALK
Site 47T802GERLMLHTNTVTVTT
Site 48T804RLMLHTNTVTVTTYN
Site 49T823ILTEQVCTQVVHKPH
Site 50S835KPHPEPDSTVKIQNP
Site 51T836PHPEPDSTVKIQNPM
Site 52T856ATLLKNSTPSAELME
Site 53S877SDMIKLFSNSRENRR
Site 54Y901DWMFSLGYINPKNSE
Site 55Y930LLYHAIKYEWGGWRV
Site 56T941GWRVWVDTLSIAHSK
Site 57S947DTLSIAHSKVTYEAH
Site 58Y951IAHSKVTYEAHKEYL
Site 59Y965LAKMYEEYQRQEEEN
Site 60S982KGKKGNVSTISGLSS
Site 61T983GKKGNVSTISGLSSQ
Site 62S985KGNVSTISGLSSQTT
Site 63S989STISGLSSQTTGAKG
Site 64T992SGLSSQTTGAKGGME
Site 65S1007IREIEDLSQSQSPES
Site 66S1009EIEDLSQSQSPESET
Site 67S1011 EDLSQSQSPESETDY
Site 68S1014SQSQSPESETDYPVS
Site 69T1016SQSPESETDYPVSTD
Site 70Y1018SPESETDYPVSTDTR
Site 71S1021SETDYPVSTDTRDLL
Site 72T1022ETDYPVSTDTRDLLM
Site 73S1030DTRDLLMSTKVSDDI
Site 74S1041SDDILGNSDRPGSGV
Site 75S1046GNSDRPGSGVHVEVH
Site 76S1077KLDDMDLSPETLVGG
Site 77T1080DMDLSPETLVGGENG
Site 78S1142EKEDLPNSSTSFLFD
Site 79S1145DLPNSSTSFLFDKIP
Site 80S1163EKLLPELSSNHIIPN
Site 81S1201VDLTCTSSIIEEKEF
Site 82T1212EKEFKIHTTSDGMSS
Site 83T1213KEFKIHTTSDGMSSI
Site 84S1214EFKIHTTSDGMSSIS
Site 85S1218HTTSDGMSSISERDL
Site 86S1219TTSDGMSSISERDLA
Site 87S1221SDGMSSISERDLASS
Site 88S1228SERDLASSTKGLEYA
Site 89T1240EYAEMTATTLETESS
Site 90T1244MTATTLETESSSSKI
Site 91S1247TTLETESSSSKIVPN
Site 92S1259VPNIDAGSIISDTER
Site 93S1262IDAGSIISDTERSDD
Site 94T1264AGSIISDTERSDDGK
Site 95S1267IISDTERSDDGKESG
Site 96T1283EIRKIQTTTTTQAVQ
Site 97T1295AVQGRSITQQDRDLR
Site 98T1313GFRGMPMTEEQRRQF
Site 99S1321 EEQRRQFSPGPRTTM
Site 100T1327FSPGPRTTMFRIPEF
Site 101S1337RIPEFKWSPMHQRLL
Site 102S1365WRSHSTKSVMDFVNS
Site 103S1409PLLSAATSPTVSKTE
Site 104T1411LSAATSPTVSKTELE
Site 105S1413AATSPTVSKTELENI
Site 106S1454FASSLNFSEIEAEKN
Site 107S1497QRDRGNKSSHGSSKP
Site 108S1498RDRGNKSSHGSSKPQ
Site 109S1501GNKSSHGSSKPQEVP
Site 110S1502NKSSHGSSKPQEVPQ
Site 111S1510KPQEVPQSVTATAAS
Site 112T1512QEVPQSVTATAASKT
Site 113S1517SVTATAASKTPLENV
Site 114T1519TATAASKTPLENVPG
Site 115S1529 ENVPGNLSPIKDPDR
Site 116S1557VFRDVDDSKQAQFLA
Site 117S1572LAVVYFISVLMVSKY
Site 118Y1579SVLMVSKYRDILEPQ
Site 119T1589ILEPQRETTRTGSQP
Site 120T1590LEPQRETTRTGSQPG
Site 121T1592PQRETTRTGSQPGRN
Site 122S1594RETTRTGSQPGRNIR
Site 123S1606NIRQEINSPTSTVVV
Site 124S1609QEINSPTSTVVVIPS
Site 125S1635AKLIPEQSFGHSFYK
Site 126S1639PEQSFGHSFYKETPA
Site 127T1644GHSFYKETPAAFPDT
Site 128T1651TPAAFPDTIKEKETP
Site 129T1657DTIKEKETPTPGEDI
Site 130T1659IKEKETPTPGEDIQV
Site 131S1669EDIQVESSIPHTDSG
Site 132T1673VESSIPHTDSGIGEE
Site 133S1675SSIPHTDSGIGEEQV
Site 134S1694NGAELETSTGPDAMS
Site 135S1701STGPDAMSELLSTLS
Site 136S1705DAMSELLSTLSSEVK
Site 137T1706AMSELLSTLSSEVKK
Site 138S1708SELLSTLSSEVKKSQ
Site 139S1709ELLSTLSSEVKKSQE
Site 140S1714LSSEVKKSQESLTEN
Site 141S1717EVKKSQESLTENPSE
Site 142T1719KKSQESLTENPSETL
Site 143S1723ESLTENPSETLKPAT
Site 144T1725LTENPSETLKPATSI
Site 145T1730SETLKPATSISSISQ
Site 146S1731ETLKPATSISSISQT
Site 147S1733LKPATSISSISQTKG
Site 148S1736ATSISSISQTKGINV
Site 149T1738SISSISQTKGINVKE
Site 150Y1767CGPEPIPYPDPALKR
Site 151T1776DPALKRETQAILPMQ
Site 152S1790QFHSFDRSVVVPVKK
Site 153T1819TAGSGLPTGSTSNIF
Site 154S1835ATGATPKSMINTTGA
Site 155T1839TPKSMINTTGAVDSG
Site 156S1845NTTGAVDSGSSSSSS
Site 157S1847TGAVDSGSSSSSSSS
Site 158S1848GAVDSGSSSSSSSSS
Site 159S1849AVDSGSSSSSSSSSF
Site 160S1850VDSGSSSSSSSSSFV
Site 161S1851DSGSSSSSSSSSFVN
Site 162S1852SGSSSSSSSSSFVNG
Site 163S1853GSSSSSSSSSFVNGA
Site 164S1854SSSSSSSSSFVNGAT
Site 165S1855SSSSSSSSFVNGATS
Site 166T1870KNLPAVQTVAPMPED
Site 167S1878VAPMPEDSAENMSIT
Site 168S1883EDSAENMSITAKLER
Site 169T2035AKHRDHVTANQLKQK
Site 170Y2070HDFWRLDYWEDDLRR
Site 171S2110TEEDVVKSKKTFRSQ
Site 172T2113DVVKSKKTFRSQAIV
Site 173S2116KSKKTFRSQAIVNQN
Site 174S2138EGDDDAVSLLQEKEI
Site 175Y2179SITTTEIYFEVDEDD
Site 176S2187FEVDEDDSAFKKIDT
Site 177S2217SEIRAVFSRRYLLQN
Site 178Y2220RAVFSRRYLLQNTAL
Site 179T2246FNFPDQATVKKVVYS
Site 180Y2263RVGVGTSYGLPQARR
Site 181S2272LPQARRISLATPRQL
Site 182T2275ARRISLATPRQLYKS
Site 183Y2280LATPRQLYKSSNMTQ
Site 184S2282TPRQLYKSSNMTQRW
Site 185T2286LYKSSNMTQRWQRRE
Site 186Y2311NTIAGRTYNDLNQYP
Site 187Y2317TYNDLNQYPVFPWVL
Site 188T2325PVFPWVLTNYESEEL
Site 189Y2327FPWVLTNYESEELDL
Site 190T2335ESEELDLTLPGNFRD
Site 191S2344PGNFRDLSKPIGALN
Site 192T2364FYAERYETWEDDQSP
Site 193Y2373EDDQSPPYHYNTHYS
Site 194T2377SPPYHYNTHYSTATS
Site 195Y2379PYHYNTHYSTATSTL
Site 196S2384THYSTATSTLSWLVR
Site 197T2413KFDHPDRTFSSVARS
Site 198S2415DHPDRTFSSVARSWR
Site 199S2416HPDRTFSSVARSWRT
Site 200S2420TFSSVARSWRTSQRD
Site 201S2424VARSWRTSQRDTSDV
Site 202T2428WRTSQRDTSDVKELI
Site 203S2429RTSQRDTSDVKELIP
Site 204Y2504WIDLIFGYKQRGPEA
Site 205S2526HYLTYEGSVNLDSIT
Site 206S2531EGSVNLDSITDPVLR
Site 207T2533SVNLDSITDPVLREA
Site 208T2551QIQNFGQTPSQLLIE
Site 209S2553QNFGQTPSQLLIEPH
Site 210S2564IEPHPPRSSAMHLCF
Site 211S2565EPHPPRSSAMHLCFL
Site 212S2575HLCFLPQSPLMFKDQ
Site 213T2632AVNRWHNTVGLRGAP
Site 214Y2641GLRGAPGYSLDQAHH
Site 215S2642LRGAPGYSLDQAHHL
Site 216S2661DPLIANNSGVNKRQI
Site 217T2669GVNKRQITDLVDQSI
Site 218Y2705WDKSFRVYSTETGKL
Site 219S2706DKSFRVYSTETGKLT
Site 220T2707KSFRVYSTETGKLTQ
Site 221T2713STETGKLTQIVFGHW
Site 222T2724FGHWDVVTCLARSES
Site 223S2731TCLARSESYIGGDCY
Site 224Y2738SYIGGDCYIVSGSRD
Site 225S2741GGDCYIVSGSRDATL
Site 226T2747VSGSRDATLLLWYWS
Site 227S2766IIGDNPNSSDYPAPR
Site 228S2767IGDNPNSSDYPAPRA
Site 229Y2769DNPNSSDYPAPRAVL
Site 230Y2840SEGHCIIYYERGRFS
Site 231Y2841EGHCIIYYERGRFSN
Site 232S2847YYERGRFSNFSINGK
Site 233S2850RGRFSNFSINGKLLA
Site 234S2864AQMEINDSTRAILLS
Site 235T2865QMEINDSTRAILLSS
Site 236Y2900DFKQLYIYPGCDAGI
Site 237S2913GIRAMDLSHDQRTLI
Site 238T2918DLSHDQRTLITGMAS
Site 239T2921HDQRTLITGMASGSI
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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