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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NOXO1
Full Name:
NADPH oxidase organizer 1
Alias:
NADPH oxidase regulatory protein;Nox organizer 1;Nox-organizing protein 1;SH3 and PX domain-containing protein 5
Type:
Mass (Da):
41253
Number AA:
376
UniProt ID:
Q8NFA2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
R
L
Q
T
F
A
F
S
V
R
W
S
D
G
S
Site 2
S31
F
A
F
S
V
R
W
S
D
G
S
D
T
F
V
Site 3
S34
S
V
R
W
S
D
G
S
D
T
F
V
R
R
S
Site 4
T36
R
W
S
D
G
S
D
T
F
V
R
R
S
W
D
Site 5
S41
S
D
T
F
V
R
R
S
W
D
E
F
R
Q
L
Site 6
T51
E
F
R
Q
L
K
K
T
L
K
E
T
F
P
V
Site 7
T55
L
K
K
T
L
K
E
T
F
P
V
E
A
G
L
Site 8
S66
E
A
G
L
L
R
R
S
D
R
V
L
P
K
L
Site 9
S78
P
K
L
L
G
Q
A
S
L
D
A
P
L
L
G
Site 10
S91
L
G
R
V
G
R
T
S
R
G
L
A
R
L
Q
Site 11
T102
A
R
L
Q
L
L
E
T
Y
S
R
R
L
L
A
Site 12
Y103
R
L
Q
L
L
E
T
Y
S
R
R
L
L
A
T
Site 13
T110
Y
S
R
R
L
L
A
T
A
E
R
V
A
R
S
Site 14
S117
T
A
E
R
V
A
R
S
P
T
I
T
G
F
F
Site 15
T119
E
R
V
A
R
S
P
T
I
T
G
F
F
A
P
Site 16
S139
E
P
A
L
P
P
G
S
R
V
I
L
P
T
P
Site 17
T145
G
S
R
V
I
L
P
T
P
E
E
Q
P
L
S
Site 18
S152
T
P
E
E
Q
P
L
S
R
A
A
G
R
L
S
Site 19
S159
S
R
A
A
G
R
L
S
I
H
S
L
E
A
Q
Site 20
S162
A
G
R
L
S
I
H
S
L
E
A
Q
S
L
R
Site 21
S167
I
H
S
L
E
A
Q
S
L
R
C
L
Q
P
F
Site 22
T176
R
C
L
Q
P
F
C
T
Q
D
T
R
D
R
P
Site 23
S191
F
Q
A
Q
A
Q
E
S
L
D
V
L
L
R
H
Site 24
T212
V
E
N
E
D
R
Q
T
A
W
F
P
A
P
Y
Site 25
S234
Q
G
R
E
G
G
P
S
L
G
S
S
G
P
Q
Site 26
S237
E
G
G
P
S
L
G
S
S
G
P
Q
F
C
A
Site 27
S238
G
G
P
S
L
G
S
S
G
P
Q
F
C
A
S
Site 28
S245
S
G
P
Q
F
C
A
S
R
A
Y
E
S
S
R
Site 29
Y248
Q
F
C
A
S
R
A
Y
E
S
S
R
A
D
E
Site 30
S251
A
S
R
A
Y
E
S
S
R
A
D
E
L
S
V
Site 31
S257
S
S
R
A
D
E
L
S
V
P
A
G
A
R
V
Site 32
Y279
R
G
W
W
L
C
R
Y
G
D
R
A
G
L
L
Site 33
T303
L
G
A
L
L
S
G
T
G
F
R
G
G
D
D
Site 34
S322
A
R
G
F
P
E
P
S
Q
A
T
A
P
P
P
Site 35
T325
F
P
E
P
S
Q
A
T
A
P
P
P
T
V
P
Site 36
T330
Q
A
T
A
P
P
P
T
V
P
T
R
P
S
P
Site 37
T333
A
P
P
P
T
V
P
T
R
P
S
P
G
A
I
Site 38
S336
P
T
V
P
T
R
P
S
P
G
A
I
Q
S
R
Site 39
S342
P
S
P
G
A
I
Q
S
R
C
C
T
V
T
R
Site 40
T346
A
I
Q
S
R
C
C
T
V
T
R
R
A
L
E
Site 41
T348
Q
S
R
C
C
T
V
T
R
R
A
L
E
R
R
Site 42
S368
R
P
R
G
C
V
D
S
V
P
H
P
T
T
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation