KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZNF397
Full Name:
Zinc finger protein 397
Alias:
Zinc finger and SCAN domain-containing protein 15; Zinc finger protein 47
Type:
Transcription factor
Mass (Da):
61139
Number AA:
534
UniProt ID:
Q8NF99
International Prot ID:
IPI00168810
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S31
V
K
V
E
D
N
F
S
W
D
E
K
F
K
Q
Site 2
S41
E
K
F
K
Q
N
G
S
T
Q
S
C
Q
E
L
Site 3
Y58
Q
Q
F
R
K
F
C
Y
Q
E
T
P
G
P
R
Site 4
T61
R
K
F
C
Y
Q
E
T
P
G
P
R
E
A
L
Site 5
S69
P
G
P
R
E
A
L
S
R
L
Q
E
L
C
Y
Site 6
Y76
S
R
L
Q
E
L
C
Y
Q
W
L
M
P
E
L
Site 7
S117
V
Q
Q
H
N
P
E
S
G
E
E
A
V
T
L
Site 8
T123
E
S
G
E
E
A
V
T
L
L
E
D
L
E
R
Site 9
S142
P
G
Q
Q
V
P
A
S
P
Q
G
P
A
V
P
Site 10
T154
A
V
P
W
K
D
L
T
C
L
R
A
S
Q
E
Site 11
S159
D
L
T
C
L
R
A
S
Q
E
S
T
D
I
H
Site 12
S162
C
L
R
A
S
Q
E
S
T
D
I
H
L
Q
P
Site 13
T163
L
R
A
S
Q
E
S
T
D
I
H
L
Q
P
L
Site 14
T172
I
H
L
Q
P
L
K
T
Q
L
K
S
W
K
P
Site 15
S176
P
L
K
T
Q
L
K
S
W
K
P
C
L
S
P
Site 16
S182
K
S
W
K
P
C
L
S
P
K
S
D
C
E
N
Site 17
S185
K
P
C
L
S
P
K
S
D
C
E
N
S
E
T
Site 18
S190
P
K
S
D
C
E
N
S
E
T
A
T
K
E
G
Site 19
T192
S
D
C
E
N
S
E
T
A
T
K
E
G
I
S
Site 20
T194
C
E
N
S
E
T
A
T
K
E
G
I
S
E
E
Site 21
S203
E
G
I
S
E
E
K
S
Q
G
L
P
Q
E
P
Site 22
S211
Q
G
L
P
Q
E
P
S
F
R
G
I
S
E
H
Site 23
S216
E
P
S
F
R
G
I
S
E
H
E
S
N
L
V
Site 24
S220
R
G
I
S
E
H
E
S
N
L
V
W
K
Q
G
Site 25
T230
V
W
K
Q
G
S
A
T
G
E
K
L
R
S
P
Site 26
S236
A
T
G
E
K
L
R
S
P
S
Q
G
G
S
F
Site 27
S238
G
E
K
L
R
S
P
S
Q
G
G
S
F
S
Q
Site 28
S242
R
S
P
S
Q
G
G
S
F
S
Q
V
I
F
T
Site 29
S244
P
S
Q
G
G
S
F
S
Q
V
I
F
T
N
K
Site 30
S252
Q
V
I
F
T
N
K
S
L
G
K
R
D
L
Y
Site 31
Y259
S
L
G
K
R
D
L
Y
D
E
A
E
R
C
L
Site 32
Y285
V
P
P
E
E
R
P
Y
R
C
D
V
C
G
H
Site 33
S298
G
H
S
F
K
Q
H
S
S
L
T
Q
H
Q
R
Site 34
S299
H
S
F
K
Q
H
S
S
L
T
Q
H
Q
R
I
Site 35
T308
T
Q
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 36
S326
G
K
A
F
S
L
R
S
Y
L
I
I
H
Q
R
Site 37
Y341
I
H
S
G
E
K
A
Y
E
C
S
E
C
G
K
Site 38
S354
G
K
A
F
N
Q
S
S
A
L
I
R
H
R
K
Site 39
S379
N
E
C
G
K
A
F
S
Q
S
S
Y
L
I
I
Site 40
S381
C
G
K
A
F
S
Q
S
S
Y
L
I
I
H
Q
Site 41
S382
G
K
A
F
S
Q
S
S
Y
L
I
I
H
Q
R
Site 42
Y383
K
A
F
S
Q
S
S
Y
L
I
I
H
Q
R
I
Site 43
T392
I
I
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 44
Y397
I
H
T
G
E
K
P
Y
E
C
N
E
C
G
K
Site 45
T405
E
C
N
E
C
G
K
T
F
S
Q
S
S
K
L
Site 46
S407
N
E
C
G
K
T
F
S
Q
S
S
K
L
I
R
Site 47
S409
C
G
K
T
F
S
Q
S
S
K
L
I
R
H
Q
Site 48
T420
I
R
H
Q
R
I
H
T
G
E
R
P
Y
E
C
Site 49
Y425
I
H
T
G
E
R
P
Y
E
C
N
E
C
G
K
Site 50
S437
C
G
K
A
F
R
Q
S
S
E
L
I
T
H
Q
Site 51
S438
G
K
A
F
R
Q
S
S
E
L
I
T
H
Q
R
Site 52
T442
R
Q
S
S
E
L
I
T
H
Q
R
I
H
S
G
Site 53
S448
I
T
H
Q
R
I
H
S
G
E
K
P
Y
E
C
Site 54
Y453
I
H
S
G
E
K
P
Y
E
C
S
E
C
G
K
Site 55
S456
G
E
K
P
Y
E
C
S
E
C
G
K
A
F
S
Site 56
S463
S
E
C
G
K
A
F
S
L
S
S
N
L
I
R
Site 57
S465
C
G
K
A
F
S
L
S
S
N
L
I
R
H
Q
Site 58
S476
I
R
H
Q
R
I
H
S
G
E
E
P
Y
Q
C
Site 59
Y481
I
H
S
G
E
E
P
Y
Q
C
N
E
C
G
K
Site 60
T489
Q
C
N
E
C
G
K
T
F
K
R
S
S
A
L
Site 61
S494
G
K
T
F
K
R
S
S
A
L
V
Q
H
Q
R
Site 62
Y509
I
H
S
G
D
E
A
Y
I
C
N
E
C
G
K
Site 63
S522
G
K
A
F
R
H
R
S
V
L
M
R
H
Q
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation