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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM48A
Full Name:
Protein FAM48A
Alias:
BA421P11.4; C13; C13orf19; FA48A; Family with sequence similarity 48, member A; FP757; P38 interacting protein; P38-interacting protein; P38IP; Transcription factor (p38 interacting protein); Tumor rejection antigen
Type:
Unknown function
Mass (Da):
85817
Number AA:
779
UniProt ID:
Q8NEM7
International Prot ID:
IPI00414255
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y14
L
A
L
D
R
A
E
Y
V
I
E
S
A
R
Q
Site 2
S18
R
A
E
Y
V
I
E
S
A
R
Q
R
P
P
K
Site 3
Y28
Q
R
P
P
K
R
K
Y
L
S
S
G
R
K
S
Site 4
S30
P
P
K
R
K
Y
L
S
S
G
R
K
S
V
F
Site 5
S31
P
K
R
K
Y
L
S
S
G
R
K
S
V
F
Q
Site 6
S35
Y
L
S
S
G
R
K
S
V
F
Q
K
L
Y
D
Site 7
Y41
K
S
V
F
Q
K
L
Y
D
L
Y
I
E
E
C
Site 8
Y44
F
Q
K
L
Y
D
L
Y
I
E
E
C
E
K
E
Site 9
Y81
S
C
L
V
V
N
L
Y
P
G
N
E
G
Y
S
Site 10
Y87
L
Y
P
G
N
E
G
Y
S
L
M
L
R
G
K
Site 11
S88
Y
P
G
N
E
G
Y
S
L
M
L
R
G
K
N
Site 12
S97
M
L
R
G
K
N
G
S
D
S
E
T
I
R
L
Site 13
S99
R
G
K
N
G
S
D
S
E
T
I
R
L
P
Y
Site 14
T101
K
N
G
S
D
S
E
T
I
R
L
P
Y
E
E
Site 15
Y106
S
E
T
I
R
L
P
Y
E
E
G
E
L
L
E
Site 16
Y114
E
E
G
E
L
L
E
Y
L
D
A
E
E
L
P
Site 17
Y148
V
I
A
E
I
R
D
Y
R
Q
S
S
N
M
K
Site 18
S151
E
I
R
D
Y
R
Q
S
S
N
M
K
S
P
G
Site 19
S152
I
R
D
Y
R
Q
S
S
N
M
K
S
P
G
Y
Site 20
S156
R
Q
S
S
N
M
K
S
P
G
Y
Q
S
R
H
Site 21
Y159
S
N
M
K
S
P
G
Y
Q
S
R
H
I
L
L
Site 22
Y224
C
T
A
N
R
L
L
Y
N
K
Q
K
M
N
T
Site 23
Y241
M
K
R
C
F
K
R
Y
S
R
S
S
L
N
R
Site 24
S242
K
R
C
F
K
R
Y
S
R
S
S
L
N
R
Q
Site 25
S244
C
F
K
R
Y
S
R
S
S
L
N
R
Q
Q
D
Site 26
S245
F
K
R
Y
S
R
S
S
L
N
R
Q
Q
D
L
Site 27
S253
L
N
R
Q
Q
D
L
S
H
C
P
P
P
P
Q
Site 28
S296
C
V
D
M
W
K
R
S
P
C
N
L
A
I
P
Site 29
Y311
S
E
V
D
V
E
K
Y
A
K
V
E
K
S
I
Site 30
S317
K
Y
A
K
V
E
K
S
I
K
S
D
D
S
Q
Site 31
S320
K
V
E
K
S
I
K
S
D
D
S
Q
P
T
V
Site 32
S323
K
S
I
K
S
D
D
S
Q
P
T
V
W
P
A
Site 33
T326
K
S
D
D
S
Q
P
T
V
W
P
A
H
D
V
Site 34
Y337
A
H
D
V
K
D
D
Y
V
F
E
C
E
A
G
Site 35
Y347
E
C
E
A
G
T
Q
Y
Q
K
T
K
L
T
I
Site 36
T350
A
G
T
Q
Y
Q
K
T
K
L
T
I
L
Q
S
Site 37
T353
Q
Y
Q
K
T
K
L
T
I
L
Q
S
L
G
D
Site 38
S357
T
K
L
T
I
L
Q
S
L
G
D
P
L
Y
Y
Site 39
Y363
Q
S
L
G
D
P
L
Y
Y
G
K
I
Q
P
C
Site 40
Y364
S
L
G
D
P
L
Y
Y
G
K
I
Q
P
C
K
Site 41
S376
P
C
K
A
D
E
E
S
D
S
Q
M
S
P
S
Site 42
S378
K
A
D
E
E
S
D
S
Q
M
S
P
S
H
S
Site 43
S381
E
E
S
D
S
Q
M
S
P
S
H
S
S
T
D
Site 44
S383
S
D
S
Q
M
S
P
S
H
S
S
T
D
D
H
Site 45
S385
S
Q
M
S
P
S
H
S
S
T
D
D
H
S
N
Site 46
S386
Q
M
S
P
S
H
S
S
T
D
D
H
S
N
W
Site 47
T387
M
S
P
S
H
S
S
T
D
D
H
S
N
W
F
Site 48
Y409
A
E
R
V
V
N
Q
Y
Q
E
L
V
Q
N
E
Site 49
S424
A
K
C
P
V
K
M
S
H
S
S
S
G
S
A
Site 50
S426
C
P
V
K
M
S
H
S
S
S
G
S
A
S
L
Site 51
S427
P
V
K
M
S
H
S
S
S
G
S
A
S
L
S
Site 52
S428
V
K
M
S
H
S
S
S
G
S
A
S
L
S
Q
Site 53
S430
M
S
H
S
S
S
G
S
A
S
L
S
Q
V
S
Site 54
S432
H
S
S
S
G
S
A
S
L
S
Q
V
S
P
G
Site 55
S434
S
S
G
S
A
S
L
S
Q
V
S
P
G
K
E
Site 56
S437
S
A
S
L
S
Q
V
S
P
G
K
E
T
D
Q
Site 57
T445
P
G
K
E
T
D
Q
T
E
T
V
S
V
Q
S
Site 58
T447
K
E
T
D
Q
T
E
T
V
S
V
Q
S
S
V
Site 59
S449
T
D
Q
T
E
T
V
S
V
Q
S
S
V
L
G
Site 60
S453
E
T
V
S
V
Q
S
S
V
L
G
K
G
V
K
Site 61
S470
P
P
P
I
K
L
P
S
S
S
G
N
S
S
S
Site 62
S471
P
P
I
K
L
P
S
S
S
G
N
S
S
S
G
Site 63
S472
P
I
K
L
P
S
S
S
G
N
S
S
S
G
N
Site 64
S475
L
P
S
S
S
G
N
S
S
S
G
N
Y
F
T
Site 65
S476
P
S
S
S
G
N
S
S
S
G
N
Y
F
T
P
Site 66
S477
S
S
S
G
N
S
S
S
G
N
Y
F
T
P
Q
Site 67
Y480
G
N
S
S
S
G
N
Y
F
T
P
Q
Q
T
S
Site 68
T482
S
S
S
G
N
Y
F
T
P
Q
Q
T
S
S
F
Site 69
S488
F
T
P
Q
Q
T
S
S
F
L
K
S
P
T
P
Site 70
S492
Q
T
S
S
F
L
K
S
P
T
P
P
P
S
S
Site 71
T494
S
S
F
L
K
S
P
T
P
P
P
S
S
K
P
Site 72
S498
K
S
P
T
P
P
P
S
S
K
P
S
S
I
P
Site 73
S499
S
P
T
P
P
P
S
S
K
P
S
S
I
P
R
Site 74
S502
P
P
P
S
S
K
P
S
S
I
P
R
K
S
S
Site 75
S503
P
P
S
S
K
P
S
S
I
P
R
K
S
S
V
Site 76
S508
P
S
S
I
P
R
K
S
S
V
D
L
N
Q
V
Site 77
S509
S
S
I
P
R
K
S
S
V
D
L
N
Q
V
S
Site 78
S519
L
N
Q
V
S
M
L
S
P
A
A
L
S
P
A
Site 79
S524
M
L
S
P
A
A
L
S
P
A
S
S
S
Q
R
Site 80
S527
P
A
A
L
S
P
A
S
S
S
Q
R
T
T
A
Site 81
S528
A
A
L
S
P
A
S
S
S
Q
R
T
T
A
T
Site 82
S529
A
L
S
P
A
S
S
S
Q
R
T
T
A
T
Q
Site 83
T533
A
S
S
S
Q
R
T
T
A
T
Q
V
M
A
N
Site 84
T535
S
S
Q
R
T
T
A
T
Q
V
M
A
N
S
A
Site 85
S615
P
F
G
L
K
N
T
S
S
L
R
P
L
N
L
Site 86
S616
F
G
L
K
N
T
S
S
L
R
P
L
N
L
L
Site 87
T634
G
G
S
L
I
F
N
T
L
Q
Q
Q
Q
Q
Q
Site 88
S643
Q
Q
Q
Q
Q
Q
L
S
Q
F
T
P
Q
Q
P
Site 89
T646
Q
Q
Q
L
S
Q
F
T
P
Q
Q
P
Q
Q
P
Site 90
T655
Q
Q
P
Q
Q
P
T
T
C
S
P
Q
Q
P
G
Site 91
S657
P
Q
Q
P
T
T
C
S
P
Q
Q
P
G
E
Q
Site 92
S666
Q
Q
P
G
E
Q
G
S
E
Q
G
S
T
S
Q
Site 93
S670
E
Q
G
S
E
Q
G
S
T
S
Q
E
Q
A
L
Site 94
T671
Q
G
S
E
Q
G
S
T
S
Q
E
Q
A
L
S
Site 95
S672
G
S
E
Q
G
S
T
S
Q
E
Q
A
L
S
A
Site 96
S678
T
S
Q
E
Q
A
L
S
A
Q
Q
A
A
V
I
Site 97
S702
Q
S
Q
A
A
V
L
S
Q
L
G
S
V
E
N
Site 98
S706
A
V
L
S
Q
L
G
S
V
E
N
R
P
E
Q
Site 99
S723
P
Q
Q
R
F
Q
L
S
S
A
F
Q
Q
Q
Q
Site 100
S724
Q
Q
R
F
Q
L
S
S
A
F
Q
Q
Q
Q
Q
Site 101
T761
Q
L
H
H
H
R
H
T
G
S
Q
S
K
S
K
Site 102
S763
H
H
H
R
H
T
G
S
Q
S
K
S
K
M
K
Site 103
S767
H
T
G
S
Q
S
K
S
K
M
K
R
G
T
P
Site 104
T773
K
S
K
M
K
R
G
T
P
T
T
P
K
F
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation