KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FAM83F
Full Name:
Protein FAM83F
Alias:
FA83F; family with sequence similarity 83 member F; family with sequence similarity 83, member F
Type:
Unknown function
Mass (Da):
55486
Number AA:
500
UniProt ID:
Q8NEG4
International Prot ID:
IPI00335121
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
A
E
S
Q
L
N
C
L
D
E
Site 2
Y27
E
A
Q
A
A
F
Y
Y
C
E
R
R
R
A
A
Site 3
Y46
L
G
G
G
E
Q
A
Y
R
E
R
L
K
E
E
Site 4
S60
E
Q
L
R
D
F
L
S
S
P
E
R
Q
A
L
Site 5
S61
Q
L
R
D
F
L
S
S
P
E
R
Q
A
L
R
Site 6
S72
Q
A
L
R
A
A
W
S
P
Y
E
D
A
V
P
Site 7
S87
A
A
N
A
R
G
K
S
K
A
K
A
K
A
P
Site 8
S101
P
A
P
A
P
A
E
S
G
E
S
L
A
Y
W
Site 9
S104
A
P
A
E
S
G
E
S
L
A
Y
W
P
D
R
Site 10
Y107
E
S
G
E
S
L
A
Y
W
P
D
R
S
D
T
Site 11
S112
L
A
Y
W
P
D
R
S
D
T
E
V
P
P
L
Site 12
T114
Y
W
P
D
R
S
D
T
E
V
P
P
L
D
L
Site 13
T124
P
P
L
D
L
G
W
T
D
T
G
F
Y
R
G
Site 14
T126
L
D
L
G
W
T
D
T
G
F
Y
R
G
V
S
Site 15
Y129
G
W
T
D
T
G
F
Y
R
G
V
S
R
V
T
Site 16
S133
T
G
F
Y
R
G
V
S
R
V
T
L
F
T
H
Site 17
T136
Y
R
G
V
S
R
V
T
L
F
T
H
P
P
K
Site 18
T139
V
S
R
V
T
L
F
T
H
P
P
K
D
E
K
Site 19
Y203
L
D
E
A
G
V
K
Y
F
L
E
M
C
Q
D
Site 20
T241
P
M
G
R
I
K
G
T
L
S
S
R
F
L
M
Site 21
S243
G
R
I
K
G
T
L
S
S
R
F
L
M
V
D
Site 22
S258
G
D
K
V
A
T
G
S
Y
R
F
T
W
S
S
Site 23
T262
A
T
G
S
Y
R
F
T
W
S
S
S
H
V
D
Site 24
S264
G
S
Y
R
F
T
W
S
S
S
H
V
D
R
N
Site 25
S265
S
Y
R
F
T
W
S
S
S
H
V
D
R
N
L
Site 26
S266
Y
R
F
T
W
S
S
S
H
V
D
R
N
L
L
Site 27
T286
Q
N
V
E
P
F
D
T
E
F
R
E
L
Y
A
Site 28
Y292
D
T
E
F
R
E
L
Y
A
I
S
E
E
V
D
Site 29
Y301
I
S
E
E
V
D
L
Y
R
Q
L
S
L
A
G
Site 30
Y314
A
G
R
V
G
L
H
Y
S
S
T
V
A
R
K
Site 31
S315
G
R
V
G
L
H
Y
S
S
T
V
A
R
K
L
Site 32
T317
V
G
L
H
Y
S
S
T
V
A
R
K
L
I
N
Site 33
Y327
R
K
L
I
N
P
K
Y
A
L
V
S
G
C
R
Site 34
S331
N
P
K
Y
A
L
V
S
G
C
R
H
P
P
G
Site 35
S363
E
G
Q
E
E
G
A
S
G
G
E
S
A
W
R
Site 36
S367
E
G
A
S
G
G
E
S
A
W
R
L
E
S
F
Site 37
S373
E
S
A
W
R
L
E
S
F
L
K
D
L
V
T
Site 38
S397
P
I
P
L
G
E
L
S
Q
K
D
G
R
M
V
Site 39
S405
Q
K
D
G
R
M
V
S
H
M
H
R
D
L
K
Site 40
S415
H
R
D
L
K
P
K
S
R
E
A
P
S
R
N
Site 41
S439
A
A
P
A
R
R
F
S
S
R
L
F
S
R
R
Site 42
S440
A
P
A
R
R
F
S
S
R
L
F
S
R
R
A
Site 43
S444
R
F
S
S
R
L
F
S
R
R
A
K
R
P
A
Site 44
S458
A
A
P
N
G
M
A
S
S
V
S
T
E
T
S
Site 45
S459
A
P
N
G
M
A
S
S
V
S
T
E
T
S
E
Site 46
T462
G
M
A
S
S
V
S
T
E
T
S
E
V
E
F
Site 47
S465
S
S
V
S
T
E
T
S
E
V
E
F
L
T
G
Site 48
S479
G
K
R
P
N
E
N
S
S
A
D
I
S
G
K
Site 49
S480
K
R
P
N
E
N
S
S
A
D
I
S
G
K
T
Site 50
S484
E
N
S
S
A
D
I
S
G
K
T
S
P
S
S
Site 51
T487
S
A
D
I
S
G
K
T
S
P
S
S
A
K
P
Site 52
S488
A
D
I
S
G
K
T
S
P
S
S
A
K
P
S
Site 53
S490
I
S
G
K
T
S
P
S
S
A
K
P
S
N
C
Site 54
S491
S
G
K
T
S
P
S
S
A
K
P
S
N
C
V
Site 55
S495
S
P
S
S
A
K
P
S
N
C
V
I
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation