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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SRFBP1
Full Name:
Serum response factor-binding protein 1
Alias:
BUD22; FLJ25286; P49; P49/STRAP; Rlb1; Serum response factor binding protein 1; SRF-dependent transcription regulation associated protein; SRF-dependent transcription regulation-associated protein; STRAP
Type:
Transcription, coactivator/corepressor
Mass (Da):
48634
Number AA:
429
UniProt ID:
Q8NEF9
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0048471
GO:0005737
GO:0043226
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S34
V
I
R
K
L
V
R
S
V
G
R
L
K
S
K
Site 2
S40
R
S
V
G
R
L
K
S
K
K
G
T
E
D
A
Site 3
T44
R
L
K
S
K
K
G
T
E
D
A
L
L
K
N
Site 4
T74
E
L
K
P
D
I
V
T
K
S
A
L
G
D
D
Site 5
S76
K
P
D
I
V
T
K
S
A
L
G
D
D
I
N
Site 6
S93
K
I
F
K
K
P
D
S
T
A
T
E
R
A
I
Site 7
S136
N
V
A
E
V
E
S
S
K
N
A
S
E
D
N
Site 8
S140
V
E
S
S
K
N
A
S
E
D
N
H
S
E
N
Site 9
S145
N
A
S
E
D
N
H
S
E
N
T
L
Y
S
N
Site 10
Y150
N
H
S
E
N
T
L
Y
S
N
D
N
G
S
N
Site 11
T163
S
N
L
Q
R
E
A
T
V
I
S
E
Q
K
V
Site 12
S184
A
K
K
P
I
H
N
S
K
E
K
I
A
K
M
Site 13
T199
E
H
G
P
K
A
V
T
I
A
N
S
P
S
K
Site 14
S203
K
A
V
T
I
A
N
S
P
S
K
P
S
E
K
Site 15
S205
V
T
I
A
N
S
P
S
K
P
S
E
K
D
S
Site 16
S208
A
N
S
P
S
K
P
S
E
K
D
S
V
V
S
Site 17
S212
S
K
P
S
E
K
D
S
V
V
S
L
E
S
Q
Site 18
S215
S
E
K
D
S
V
V
S
L
E
S
Q
K
T
P
Site 19
S218
D
S
V
V
S
L
E
S
Q
K
T
P
A
D
P
Site 20
T221
V
S
L
E
S
Q
K
T
P
A
D
P
K
L
K
Site 21
T229
P
A
D
P
K
L
K
T
L
S
Q
T
K
K
N
Site 22
S231
D
P
K
L
K
T
L
S
Q
T
K
K
N
K
G
Site 23
S239
Q
T
K
K
N
K
G
S
D
S
S
L
S
G
N
Site 24
S241
K
K
N
K
G
S
D
S
S
L
S
G
N
S
D
Site 25
S242
K
N
K
G
S
D
S
S
L
S
G
N
S
D
G
Site 26
S244
K
G
S
D
S
S
L
S
G
N
S
D
G
G
E
Site 27
Y260
F
C
E
E
E
K
E
Y
F
D
D
S
T
E
E
Site 28
S264
E
K
E
Y
F
D
D
S
T
E
E
R
F
Y
K
Site 29
T265
K
E
Y
F
D
D
S
T
E
E
R
F
Y
K
Q
Site 30
Y270
D
S
T
E
E
R
F
Y
K
Q
S
S
M
S
E
Site 31
S273
E
E
R
F
Y
K
Q
S
S
M
S
E
D
S
D
Site 32
S274
E
R
F
Y
K
Q
S
S
M
S
E
D
S
D
S
Site 33
S276
F
Y
K
Q
S
S
M
S
E
D
S
D
S
G
D
Site 34
S279
Q
S
S
M
S
E
D
S
D
S
G
D
D
F
F
Site 35
S281
S
M
S
E
D
S
D
S
G
D
D
F
F
I
G
Site 36
T293
F
I
G
K
V
R
R
T
R
K
K
E
S
S
C
Site 37
S298
R
R
T
R
K
K
E
S
S
C
H
S
S
V
K
Site 38
S299
R
T
R
K
K
E
S
S
C
H
S
S
V
K
E
Site 39
S302
K
K
E
S
S
C
H
S
S
V
K
E
Q
K
P
Site 40
S303
K
E
S
S
C
H
S
S
V
K
E
Q
K
P
L
Site 41
T326
T
G
E
T
H
G
D
T
R
N
D
K
I
K
P
Site 42
T335
N
D
K
I
K
P
S
T
E
T
R
K
L
E
S
Site 43
S342
T
E
T
R
K
L
E
S
V
F
F
H
S
L
S
Site 44
S347
L
E
S
V
F
F
H
S
L
S
G
S
K
S
S
Site 45
S349
S
V
F
F
H
S
L
S
G
S
K
S
S
R
R
Site 46
S351
F
F
H
S
L
S
G
S
K
S
S
R
R
N
F
Site 47
S353
H
S
L
S
G
S
K
S
S
R
R
N
F
K
E
Site 48
S354
S
L
S
G
S
K
S
S
R
R
N
F
K
E
Q
Site 49
T365
F
K
E
Q
A
P
K
T
R
S
L
D
F
P
Q
Site 50
S367
E
Q
A
P
K
T
R
S
L
D
F
P
Q
N
E
Site 51
S386
N
Q
F
N
K
K
L
S
G
R
L
E
N
T
K
Site 52
S403
L
Q
L
P
L
H
P
S
W
E
A
S
R
R
R
Site 53
S407
L
H
P
S
W
E
A
S
R
R
R
K
E
Q
Q
Site 54
S415
R
R
R
K
E
Q
Q
S
N
I
A
V
F
Q
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation