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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ACRBP
Full Name:
Acrosin-binding protein
Alias:
Cancer/testis antigen 23;Cancer/testis antigen OY-TES-1;Proacrosin-binding protein sp32
Type:
Mass (Da):
61359
Number AA:
543
UniProt ID:
Q8NEB7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
A
P
A
A
A
Q
D
S
T
Q
A
S
T
P
G
Site 2
T29
P
A
A
A
Q
D
S
T
Q
A
S
T
P
G
S
Site 3
S32
A
Q
D
S
T
Q
A
S
T
P
G
S
P
L
S
Site 4
T33
Q
D
S
T
Q
A
S
T
P
G
S
P
L
S
P
Site 5
S36
T
Q
A
S
T
P
G
S
P
L
S
P
T
E
Y
Site 6
S39
S
T
P
G
S
P
L
S
P
T
E
Y
E
R
F
Site 7
T41
P
G
S
P
L
S
P
T
E
Y
E
R
F
F
A
Site 8
Y43
S
P
L
S
P
T
E
Y
E
R
F
F
A
L
L
Site 9
T51
E
R
F
F
A
L
L
T
P
T
W
K
A
E
T
Site 10
T59
P
T
W
K
A
E
T
T
C
R
L
R
A
T
H
Site 11
T65
T
T
C
R
L
R
A
T
H
G
C
R
N
P
T
Site 12
T72
T
H
G
C
R
N
P
T
L
V
Q
L
D
Q
Y
Site 13
Y79
T
L
V
Q
L
D
Q
Y
E
N
H
G
L
V
P
Site 14
Y116
Y
R
C
S
N
H
V
Y
Y
A
K
R
V
L
C
Site 15
Y117
R
C
S
N
H
V
Y
Y
A
K
R
V
L
C
S
Site 16
S131
S
Q
P
V
S
I
L
S
P
N
T
L
K
E
I
Site 17
S141
T
L
K
E
I
E
A
S
A
E
V
S
P
T
T
Site 18
S145
I
E
A
S
A
E
V
S
P
T
T
M
T
S
P
Site 19
T147
A
S
A
E
V
S
P
T
T
M
T
S
P
I
S
Site 20
T148
S
A
E
V
S
P
T
T
M
T
S
P
I
S
P
Site 21
T150
E
V
S
P
T
T
M
T
S
P
I
S
P
H
F
Site 22
S151
V
S
P
T
T
M
T
S
P
I
S
P
H
F
T
Site 23
S154
T
T
M
T
S
P
I
S
P
H
F
T
V
T
E
Site 24
T158
S
P
I
S
P
H
F
T
V
T
E
R
Q
T
F
Site 25
T160
I
S
P
H
F
T
V
T
E
R
Q
T
F
Q
P
Site 26
T164
F
T
V
T
E
R
Q
T
F
Q
P
W
P
E
R
Site 27
S173
Q
P
W
P
E
R
L
S
N
N
V
E
E
L
L
Site 28
S182
N
V
E
E
L
L
Q
S
S
L
S
L
G
G
Q
Site 29
S183
V
E
E
L
L
Q
S
S
L
S
L
G
G
Q
E
Site 30
S185
E
L
L
Q
S
S
L
S
L
G
G
Q
E
Q
A
Site 31
T238
K
Q
E
E
G
Q
G
T
K
E
G
R
E
A
V
Site 32
T250
E
A
V
S
Q
L
Q
T
D
S
E
P
K
F
H
Site 33
S252
V
S
Q
L
Q
T
D
S
E
P
K
F
H
S
E
Site 34
S258
D
S
E
P
K
F
H
S
E
S
L
S
S
N
P
Site 35
S260
E
P
K
F
H
S
E
S
L
S
S
N
P
S
S
Site 36
S262
K
F
H
S
E
S
L
S
S
N
P
S
S
F
A
Site 37
S263
F
H
S
E
S
L
S
S
N
P
S
S
F
A
P
Site 38
S266
E
S
L
S
S
N
P
S
S
F
A
P
R
V
R
Site 39
S267
S
L
S
S
N
P
S
S
F
A
P
R
V
R
E
Site 40
T278
R
V
R
E
V
E
S
T
P
M
I
M
E
N
I
Site 41
S291
N
I
Q
E
L
I
R
S
A
Q
E
I
D
E
M
Site 42
Y302
I
D
E
M
N
E
I
Y
D
E
N
S
Y
W
R
Site 43
Y307
E
I
Y
D
E
N
S
Y
W
R
N
Q
N
P
G
Site 44
S315
W
R
N
Q
N
P
G
S
L
L
Q
L
P
H
T
Site 45
T340
V
E
N
T
C
I
I
T
P
T
A
K
A
W
K
Site 46
Y348
P
T
A
K
A
W
K
Y
M
E
E
E
I
L
G
Site 47
S363
F
G
K
S
V
C
D
S
L
G
R
R
H
M
S
Site 48
S370
S
L
G
R
R
H
M
S
T
C
A
L
C
D
F
Site 49
S387
L
K
L
E
Q
C
H
S
E
A
S
L
Q
R
Q
Site 50
S390
E
Q
C
H
S
E
A
S
L
Q
R
Q
Q
C
D
Site 51
T398
L
Q
R
Q
Q
C
D
T
S
H
K
T
P
F
V
Site 52
T402
Q
C
D
T
S
H
K
T
P
F
V
S
P
L
L
Site 53
S406
S
H
K
T
P
F
V
S
P
L
L
A
S
Q
S
Site 54
S422
S
I
G
N
Q
V
G
S
P
E
S
G
R
F
Y
Site 55
S425
N
Q
V
G
S
P
E
S
G
R
F
Y
G
L
D
Site 56
Y429
S
P
E
S
G
R
F
Y
G
L
D
L
Y
G
G
Site 57
Y434
R
F
Y
G
L
D
L
Y
G
G
L
H
M
D
F
Site 58
T462
R
V
S
G
W
L
Q
T
E
F
L
S
F
Q
D
Site 59
S466
W
L
Q
T
E
F
L
S
F
Q
D
G
D
F
P
Site 60
Y481
T
K
I
C
D
T
D
Y
I
Q
Y
P
N
Y
C
Site 61
Y487
D
Y
I
Q
Y
P
N
Y
C
S
F
K
S
Q
Q
Site 62
S505
R
N
R
N
R
K
V
S
R
M
R
C
L
Q
N
Site 63
Y515
R
C
L
Q
N
E
T
Y
S
A
L
S
P
G
K
Site 64
S519
N
E
T
Y
S
A
L
S
P
G
K
S
E
D
V
Site 65
S523
S
A
L
S
P
G
K
S
E
D
V
V
L
R
W
Site 66
S531
E
D
V
V
L
R
W
S
Q
E
F
S
T
L
T
Site 67
S535
L
R
W
S
Q
E
F
S
T
L
T
L
G
Q
F
Site 68
T538
S
Q
E
F
S
T
L
T
L
G
Q
F
G
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation