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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GLIS3
Full Name:
Zinc finger protein GLIS3
Alias:
flj38999; flj90578; glis family zinc finger 3; glis3; mgc33662; znf515
Type:
Transcription factor
Mass (Da):
83670
Number AA:
UniProt ID:
Q8NEA6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003704
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0000122
GO:0045944
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T18
P
P
A
S
Q
V
S
T
A
C
N
Q
I
S
P
Site 2
S24
S
T
A
C
N
Q
I
S
P
S
L
Q
R
A
M
Site 3
S26
A
C
N
Q
I
S
P
S
L
Q
R
A
M
N
A
Site 4
S41
A
N
L
N
I
P
P
S
D
T
R
S
L
I
S
Site 5
S45
I
P
P
S
D
T
R
S
L
I
S
R
E
S
L
Site 6
S48
S
D
T
R
S
L
I
S
R
E
S
L
A
S
T
Site 7
S51
R
S
L
I
S
R
E
S
L
A
S
T
T
L
S
Site 8
S54
I
S
R
E
S
L
A
S
T
T
L
S
L
T
E
Site 9
T55
S
R
E
S
L
A
S
T
T
L
S
L
T
E
S
Site 10
T56
R
E
S
L
A
S
T
T
L
S
L
T
E
S
Q
Site 11
S58
S
L
A
S
T
T
L
S
L
T
E
S
Q
S
A
Site 12
T60
A
S
T
T
L
S
L
T
E
S
Q
S
A
S
S
Site 13
S62
T
T
L
S
L
T
E
S
Q
S
A
S
S
M
K
Site 14
S64
L
S
L
T
E
S
Q
S
A
S
S
M
K
Q
E
Site 15
S66
L
T
E
S
Q
S
A
S
S
M
K
Q
E
W
S
Site 16
S73
S
S
M
K
Q
E
W
S
Q
G
Y
R
A
L
P
Site 17
S81
Q
G
Y
R
A
L
P
S
L
S
N
H
G
S
Q
Site 18
S83
Y
R
A
L
P
S
L
S
N
H
G
S
Q
N
G
Site 19
S87
P
S
L
S
N
H
G
S
Q
N
G
L
D
L
G
Site 20
S104
L
S
L
P
P
G
T
S
M
S
S
N
S
V
S
Site 21
S106
L
P
P
G
T
S
M
S
S
N
S
V
S
N
S
Site 22
S107
P
P
G
T
S
M
S
S
N
S
V
S
N
S
L
Site 23
S109
G
T
S
M
S
S
N
S
V
S
N
S
L
P
S
Site 24
S111
S
M
S
S
N
S
V
S
N
S
L
P
S
Y
L
Site 25
S113
S
S
N
S
V
S
N
S
L
P
S
Y
L
F
G
Site 26
S116
S
V
S
N
S
L
P
S
Y
L
F
G
T
E
S
Site 27
Y117
V
S
N
S
L
P
S
Y
L
F
G
T
E
S
S
Site 28
T121
L
P
S
Y
L
F
G
T
E
S
S
H
S
P
Y
Site 29
S123
S
Y
L
F
G
T
E
S
S
H
S
P
Y
P
S
Site 30
S124
Y
L
F
G
T
E
S
S
H
S
P
Y
P
S
P
Site 31
S126
F
G
T
E
S
S
H
S
P
Y
P
S
P
R
H
Site 32
Y128
T
E
S
S
H
S
P
Y
P
S
P
R
H
S
S
Site 33
S130
S
S
H
S
P
Y
P
S
P
R
H
S
S
T
R
Site 34
S134
P
Y
P
S
P
R
H
S
S
T
R
S
H
S
A
Site 35
S135
Y
P
S
P
R
H
S
S
T
R
S
H
S
A
R
Site 36
T136
P
S
P
R
H
S
S
T
R
S
H
S
A
R
S
Site 37
S138
P
R
H
S
S
T
R
S
H
S
A
R
S
K
K
Site 38
S140
H
S
S
T
R
S
H
S
A
R
S
K
K
R
A
Site 39
S143
T
R
S
H
S
A
R
S
K
K
R
A
L
S
L
Site 40
S149
R
S
K
K
R
A
L
S
L
S
P
L
S
D
G
Site 41
S151
K
K
R
A
L
S
L
S
P
L
S
D
G
I
G
Site 42
T167
D
F
N
T
I
I
R
T
S
P
T
S
L
V
A
Site 43
Y175
S
P
T
S
L
V
A
Y
I
N
G
S
R
A
S
Site 44
S182
Y
I
N
G
S
R
A
S
P
A
N
L
S
P
Q
Site 45
S187
R
A
S
P
A
N
L
S
P
Q
P
E
V
Y
G
Site 46
Y193
L
S
P
Q
P
E
V
Y
G
H
F
L
G
V
R
Site 47
S202
H
F
L
G
V
R
G
S
C
I
P
Q
P
R
P
Site 48
S213
Q
P
R
P
V
P
G
S
Q
K
G
V
L
V
A
Site 49
S267
H
G
L
P
G
P
D
S
Q
S
A
G
L
F
K
Site 50
T275
Q
S
A
G
L
F
K
T
E
R
L
E
E
F
P
Site 51
S284
R
L
E
E
F
P
G
S
T
V
D
L
P
P
A
Site 52
T285
L
E
E
F
P
G
S
T
V
D
L
P
P
A
P
Site 53
Y307
P
Q
G
P
P
P
P
Y
H
A
H
A
H
L
H
Site 54
Y356
W
I
D
C
S
A
L
Y
D
Q
Q
E
E
L
V
Site 55
Y390
W
A
G
C
P
R
R
Y
K
P
F
N
A
R
Y
Site 56
S407
L
I
H
M
R
V
H
S
G
E
K
P
N
K
C
Site 57
T415
G
E
K
P
N
K
C
T
F
E
G
C
E
K
A
Site 58
S424
E
G
C
E
K
A
F
S
R
L
E
N
L
K
I
Site 59
S435
N
L
K
I
H
L
R
S
H
T
G
E
K
P
Y
Site 60
T437
K
I
H
L
R
S
H
T
G
E
K
P
Y
L
C
Site 61
Y442
S
H
T
G
E
K
P
Y
L
C
Q
H
P
G
C
Site 62
S454
P
G
C
Q
K
A
F
S
N
S
S
D
R
A
K
Site 63
S456
C
Q
K
A
F
S
N
S
S
D
R
A
K
H
Q
Site 64
S457
Q
K
A
F
S
N
S
S
D
R
A
K
H
Q
R
Site 65
Y472
T
H
L
D
T
K
P
Y
A
C
Q
I
P
G
C
Site 66
Y483
I
P
G
C
T
K
R
Y
T
D
P
S
S
L
R
Site 67
T484
P
G
C
T
K
R
Y
T
D
P
S
S
L
R
K
Site 68
S487
T
K
R
Y
T
D
P
S
S
L
R
K
H
V
K
Site 69
S488
K
R
Y
T
D
P
S
S
L
R
K
H
V
K
A
Site 70
S509
Q
A
R
K
K
L
R
S
S
T
E
L
H
P
D
Site 71
S510
A
R
K
K
L
R
S
S
T
E
L
H
P
D
L
Site 72
T511
R
K
K
L
R
S
S
T
E
L
H
P
D
L
L
Site 73
T519
E
L
H
P
D
L
L
T
D
C
L
T
V
Q
S
Site 74
S526
T
D
C
L
T
V
Q
S
L
Q
P
A
T
S
P
Site 75
S532
Q
S
L
Q
P
A
T
S
P
R
D
A
A
A
E
Site 76
T541
R
D
A
A
A
E
G
T
V
G
R
S
P
G
P
Site 77
S545
A
E
G
T
V
G
R
S
P
G
P
G
P
D
L
Site 78
Y553
P
G
P
G
P
D
L
Y
S
A
P
I
F
S
S
Site 79
S554
G
P
G
P
D
L
Y
S
A
P
I
F
S
S
N
Site 80
S559
L
Y
S
A
P
I
F
S
S
N
Y
S
S
R
S
Site 81
S560
Y
S
A
P
I
F
S
S
N
Y
S
S
R
S
G
Site 82
Y562
A
P
I
F
S
S
N
Y
S
S
R
S
G
T
A
Site 83
S563
P
I
F
S
S
N
Y
S
S
R
S
G
T
A
A
Site 84
S564
I
F
S
S
N
Y
S
S
R
S
G
T
A
A
G
Site 85
S566
S
S
N
Y
S
S
R
S
G
T
A
A
G
A
V
Site 86
T568
N
Y
S
S
R
S
G
T
A
A
G
A
V
P
P
Site 87
S580
V
P
P
P
H
P
V
S
H
P
S
P
G
H
N
Site 88
S583
P
H
P
V
S
H
P
S
P
G
H
N
V
Q
G
Site 89
S591
P
G
H
N
V
Q
G
S
P
H
N
P
S
S
Q
Site 90
S596
Q
G
S
P
H
N
P
S
S
Q
L
P
P
L
T
Site 91
S597
G
S
P
H
N
P
S
S
Q
L
P
P
L
T
A
Site 92
T603
S
S
Q
L
P
P
L
T
A
V
D
A
G
A
E
Site 93
S615
G
A
E
R
F
A
P
S
A
P
S
P
H
H
I
Site 94
S618
R
F
A
P
S
A
P
S
P
H
H
I
S
P
R
Site 95
S623
A
P
S
P
H
H
I
S
P
R
R
V
P
A
P
Site 96
S631
P
R
R
V
P
A
P
S
S
I
L
Q
R
T
Q
Site 97
S632
R
R
V
P
A
P
S
S
I
L
Q
R
T
Q
P
Site 98
T637
P
S
S
I
L
Q
R
T
Q
P
P
Y
T
Q
Q
Site 99
Y641
L
Q
R
T
Q
P
P
Y
T
Q
Q
P
S
G
S
Site 100
T642
Q
R
T
Q
P
P
Y
T
Q
Q
P
S
G
S
H
Site 101
S646
P
P
Y
T
Q
Q
P
S
G
S
H
L
K
S
Y
Site 102
S648
Y
T
Q
Q
P
S
G
S
H
L
K
S
Y
Q
P
Site 103
S652
P
S
G
S
H
L
K
S
Y
Q
P
E
T
N
S
Site 104
Y653
S
G
S
H
L
K
S
Y
Q
P
E
T
N
S
S
Site 105
T657
L
K
S
Y
Q
P
E
T
N
S
S
F
Q
P
N
Site 106
S660
Y
Q
P
E
T
N
S
S
F
Q
P
N
G
I
H
Site 107
Y683
Q
K
F
C
P
P
H
Y
P
D
S
Q
R
I
V
Site 108
S686
C
P
P
H
Y
P
D
S
Q
R
I
V
P
P
V
Site 109
S710
E
D
C
L
V
P
T
S
M
G
Q
A
S
F
D
Site 110
S715
P
T
S
M
G
Q
A
S
F
D
V
F
H
R
A
Site 111
T730
F
S
T
H
S
G
I
T
V
Y
D
L
P
S
S
Site 112
Y732
T
H
S
G
I
T
V
Y
D
L
P
S
S
S
S
Site 113
S737
T
V
Y
D
L
P
S
S
S
S
S
L
F
G
E
Site 114
S738
V
Y
D
L
P
S
S
S
S
S
L
F
G
E
S
Site 115
S739
Y
D
L
P
S
S
S
S
S
L
F
G
E
S
L
Site 116
S740
D
L
P
S
S
S
S
S
L
F
G
E
S
L
R
Site 117
S745
S
S
S
L
F
G
E
S
L
R
S
G
A
E
D
Site 118
S748
L
F
G
E
S
L
R
S
G
A
E
D
A
T
F
Site 119
T754
R
S
G
A
E
D
A
T
F
L
Q
I
S
T
V
Site 120
S759
D
A
T
F
L
Q
I
S
T
V
D
R
C
P
S
Site 121
T760
A
T
F
L
Q
I
S
T
V
D
R
C
P
S
Q
Site 122
S766
S
T
V
D
R
C
P
S
Q
L
S
S
V
Y
T
Site 123
S769
D
R
C
P
S
Q
L
S
S
V
Y
T
E
G
_
Site 124
S770
R
C
P
S
Q
L
S
S
V
Y
T
E
G
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation