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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CPEB3
Full Name:
Cytoplasmic polyadenylation element-binding protein 3
Alias:
CPE-binding protein 3; CPE-BP3; cytoplasmic polyadenylation element binding protein 3; hCPEB-3; KIAA0940
Type:
Mass (Da):
76014
Number AA:
698
UniProt ID:
Q8NE35
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0000166
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
D
D
L
L
M
D
K
S
K
T
Q
P
Q
P
Q
Site 2
S30
Q
Q
Q
P
Q
P
E
S
S
V
S
E
A
P
S
Site 3
S31
Q
Q
P
Q
P
E
S
S
V
S
E
A
P
S
T
Site 4
S33
P
Q
P
E
S
S
V
S
E
A
P
S
T
P
L
Site 5
S37
S
S
V
S
E
A
P
S
T
P
L
S
S
E
T
Site 6
T38
S
V
S
E
A
P
S
T
P
L
S
S
E
T
P
Site 7
S41
E
A
P
S
T
P
L
S
S
E
T
P
K
P
E
Site 8
S42
A
P
S
T
P
L
S
S
E
T
P
K
P
E
E
Site 9
T44
S
T
P
L
S
S
E
T
P
K
P
E
E
N
S
Site 10
S51
T
P
K
P
E
E
N
S
A
V
P
A
L
S
P
Site 11
S75
P
D
K
M
Q
M
E
S
P
L
L
P
G
L
S
Site 12
S82
S
P
L
L
P
G
L
S
F
H
Q
P
P
Q
Q
Site 13
S102
E
P
A
A
P
G
A
S
L
S
P
S
F
G
S
Site 14
S104
A
A
P
G
A
S
L
S
P
S
F
G
S
T
W
Site 15
S106
P
G
A
S
L
S
P
S
F
G
S
T
W
S
T
Site 16
S109
S
L
S
P
S
F
G
S
T
W
S
T
G
T
T
Site 17
T110
L
S
P
S
F
G
S
T
W
S
T
G
T
T
N
Site 18
S112
P
S
F
G
S
T
W
S
T
G
T
T
N
A
V
Site 19
T113
S
F
G
S
T
W
S
T
G
T
T
N
A
V
E
Site 20
T116
S
T
W
S
T
G
T
T
N
A
V
E
D
S
F
Site 21
S122
T
T
N
A
V
E
D
S
F
F
Q
G
I
T
P
Site 22
S192
Q
P
P
Q
Q
R
R
S
P
A
S
P
S
Q
A
Site 23
S195
Q
Q
R
R
S
P
A
S
P
S
Q
A
P
Y
A
Site 24
S197
R
R
S
P
A
S
P
S
Q
A
P
Y
A
Q
R
Site 25
Y201
A
S
P
S
Q
A
P
Y
A
Q
R
S
A
A
A
Site 26
T217
Y
G
H
Q
P
I
M
T
S
K
P
S
S
S
S
Site 27
S218
G
H
Q
P
I
M
T
S
K
P
S
S
S
S
A
Site 28
S221
P
I
M
T
S
K
P
S
S
S
S
A
V
A
A
Site 29
S237
A
A
A
A
A
A
S
S
A
S
S
S
W
N
T
Site 30
S239
A
A
A
A
S
S
A
S
S
S
W
N
T
H
Q
Site 31
S240
A
A
A
S
S
A
S
S
S
W
N
T
H
Q
S
Site 32
S241
A
A
S
S
A
S
S
S
W
N
T
H
Q
S
V
Site 33
T244
S
A
S
S
S
W
N
T
H
Q
S
V
N
A
A
Site 34
S253
Q
S
V
N
A
A
W
S
A
P
S
N
P
W
G
Site 35
S284
G
V
G
V
G
V
P
S
P
L
N
P
I
S
P
Site 36
S290
P
S
P
L
N
P
I
S
P
L
K
K
P
F
S
Site 37
S297
S
P
L
K
K
P
F
S
S
N
V
I
A
P
P
Site 38
S298
P
L
K
K
P
F
S
S
N
V
I
A
P
P
K
Site 39
T313
F
P
R
A
A
P
L
T
S
K
S
W
M
E
D
Site 40
S314
P
R
A
A
P
L
T
S
K
S
W
M
E
D
N
Site 41
S316
A
A
P
L
T
S
K
S
W
M
E
D
N
A
F
Site 42
S338
L
L
P
F
Q
D
R
S
R
P
Y
D
T
F
N
Site 43
Y341
F
Q
D
R
S
R
P
Y
D
T
F
N
L
H
S
Site 44
T343
D
R
S
R
P
Y
D
T
F
N
L
H
S
L
E
Site 45
S348
Y
D
T
F
N
L
H
S
L
E
N
S
L
M
D
Site 46
S352
N
L
H
S
L
E
N
S
L
M
D
M
I
R
T
Site 47
Y369
E
P
L
K
G
K
H
Y
P
P
S
G
P
P
M
Site 48
S372
K
G
K
H
Y
P
P
S
G
P
P
M
S
F
A
Site 49
S377
P
P
S
G
P
P
M
S
F
A
D
I
M
W
R
Site 50
S414
N
N
A
F
L
D
D
S
H
G
D
Q
A
L
S
Site 51
S421
S
H
G
D
Q
A
L
S
S
G
L
S
S
P
T
Site 52
S422
H
G
D
Q
A
L
S
S
G
L
S
S
P
T
R
Site 53
S425
Q
A
L
S
S
G
L
S
S
P
T
R
C
Q
N
Site 54
S426
A
L
S
S
G
L
S
S
P
T
R
C
Q
N
G
Site 55
Y439
N
G
E
R
V
E
R
Y
S
R
K
V
F
V
G
Site 56
S440
G
E
R
V
E
R
Y
S
R
K
V
F
V
G
G
Site 57
T458
D
I
D
E
D
E
I
T
A
S
F
R
R
F
G
Site 58
S460
D
E
D
E
I
T
A
S
F
R
R
F
G
P
L
Site 59
S477
D
W
P
H
K
A
E
S
K
S
Y
F
P
P
K
Site 60
S479
P
H
K
A
E
S
K
S
Y
F
P
P
K
G
Y
Site 61
Y480
H
K
A
E
S
K
S
Y
F
P
P
K
G
Y
A
Site 62
Y512
L
E
E
D
G
K
L
Y
L
C
V
S
S
P
T
Site 63
S516
G
K
L
Y
L
C
V
S
S
P
T
I
K
D
K
Site 64
S517
K
L
Y
L
C
V
S
S
P
T
I
K
D
K
P
Site 65
S533
Q
I
R
P
W
N
L
S
D
S
D
F
V
M
D
Site 66
S535
R
P
W
N
L
S
D
S
D
F
V
M
D
G
S
Site 67
S542
S
D
F
V
M
D
G
S
Q
P
L
D
P
R
K
Site 68
T550
Q
P
L
D
P
R
K
T
I
F
V
G
G
V
P
Site 69
Y573
A
M
I
M
D
R
L
Y
G
G
V
C
Y
A
G
Site 70
Y578
R
L
Y
G
G
V
C
Y
A
G
I
D
T
D
P
Site 71
T583
V
C
Y
A
G
I
D
T
D
P
E
L
K
Y
P
Site 72
Y589
D
T
D
P
E
L
K
Y
P
K
G
A
G
R
V
Site 73
S599
G
A
G
R
V
A
F
S
N
Q
Q
S
Y
I
A
Site 74
Y604
A
F
S
N
Q
Q
S
Y
I
A
A
I
S
A
R
Site 75
Y629
K
R
V
E
V
K
P
Y
V
L
D
D
Q
M
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation